Kinase-Inactive G-Protein-Coupled Receptor Kinases Are Able to Attenuate Follicle-Stimulating Hormone-Induced Signaling

2001 ◽  
Vol 282 (1) ◽  
pp. 71-78 ◽  
Author(s):  
Eric Reiter ◽  
Sébastien Marion ◽  
Fabienne Robert ◽  
Carine Troispoux ◽  
François Boulay ◽  
...  
Keyword(s):  
G Protein ◽  
Follicle Stimulating Hormone ◽  
G Protein Coupled Receptor ◽  
Receptor Kinases ◽  
G Protein Coupled ◽  
Stimulating Hormone

scholarly journals Involvement of G Protein-Coupled Receptor Kinases and Arrestins in Desensitization to Follicle-Stimulating Hormone Action

1999 ◽  
Vol 13 (9) ◽  
pp. 1599-1614 ◽  
Author(s):  
Carine Troispoux ◽  
Florian Guillou ◽  
Jean-Marc Elalouf ◽  
Dmitri Firsov ◽  
Luisa Iacovelli ◽  
...  
Keyword(s):  
G Protein ◽  
Follicle Stimulating Hormone ◽  
Hormone Action ◽  
G Protein Coupled Receptor ◽  
Receptor Kinases ◽  
G Protein Coupled ◽  
Stimulating Hormone

scholarly journals The G Protein-Coupled Receptor Kinases (GRKs) in Chemokine Receptor-Mediated Immune Cell Migration: From Molecular Cues to Physiopathology

Cells ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 75
Author(s):  
Marta Laganà ◽  
Géraldine Schlecht-Louf ◽  
Françoise Bachelerie
Keyword(s):  
G Protein ◽  
Chemokine Receptor ◽  
Immune Cell ◽  
Neutrophil Migration ◽  
G Protein Coupled Receptor ◽  
Receptor Kinases ◽  
Immune Cell Migration ◽  
And Migration ◽  
G Protein Coupled ◽  
Gpcr Desensitization

Although G protein-coupled receptor kinases (GRKs) have long been known to regulate G protein-coupled receptor (GPCR) desensitization, their more recently characterized functions as scaffolds and signalling adapters underscore that this small family of proteins governs a larger array of physiological functions than originally suspected. This review explores how GRKs contribute to the complex signalling networks involved in the migration of immune cells along chemokine gradients sensed by cell surface GPCRs. We outline emerging evidence indicating that the coordinated docking of several GRKs on an active chemokine receptor determines a specific receptor phosphorylation barcode that will translate into distinct signalling and migration outcomes. The guidance cues for neutrophil migration are emphasized based on several alterations affecting GRKs or GPCRs reported to be involved in pathological conditions.

Correlation Between Beta-Adrenoceptors and G-Protein-Coupled Receptor Kinases in Pretransplantation Heart Failure

2008 ◽  
Vol 40 (9) ◽  
pp. 3014-3016 ◽  
Author(s):  
J. Agüero ◽  
L. Almenar ◽  
P. D'Ocon ◽  
E. Oliver ◽  
F. Montó ◽  
...  
Keyword(s):  
Heart Failure ◽  
G Protein ◽  
G Protein Coupled Receptor ◽  
Beta Adrenoceptors ◽  
Receptor Kinases ◽  
G Protein Coupled
Sign in / Sign up

Export Citation Format

Share Document