Low Paraoxonase in Persian Gulf War Veterans Self-Reporting Gulf War Syndrome

2000 ◽  
Vol 276 (2) ◽  
pp. 729-733 ◽  
Author(s):  
Bharti Mackness ◽  
Paul N. Durrington ◽  
Michael I. Mackness
Keyword(s):  
Persian Gulf ◽  
Gulf War ◽  
Persian Gulf War ◽  
Gulf War Syndrome ◽  
War Veterans ◽  
Gulf War Veterans ◽  
Persian Gulf War Veterans

scholarly journals RNAs in the Sera of Persian Gulf War Veterans Have Segments Homologous to Chromosome 22q11.2

1999 ◽  
Vol 6 (3) ◽  
pp. 330-335 ◽  
Author(s):  
Howard B. Urnovitz ◽  
James J. Tuite ◽  
Jean M. Higashida ◽  
William H. Murphy
Keyword(s):  
Persian Gulf ◽  
Genetic Alterations ◽  
Gulf War ◽  
Persian Gulf War ◽  
Rt Pcr ◽  
Gulf War Syndrome ◽  
War Veterans ◽  
Gulf War Veterans ◽  
Chromosome 22Q11.2 ◽  
Persian Gulf War Veterans

ABSTRACT Reverse transcriptase PCR (RT-PCR) was used for polyribonucleotide assays with sera from deployed Persian Gulf War veterans with the Gulf War Syndrome and a cohort of nonmilitary controls. Sera from veterans contained polyribonucleotides (amplicons) that were obtained by RT-PCR and that ranged in size from 200 to ca. 2,000 bp. Sera from controls did not contain amplicons larger than 450 bp. DNA sequences were derived from two amplicons unique to veterans. These amplicons, which were 414 and 759 nucleotides, were unrelated to each other or to any sequence in gene bank databases. The amplicons contained short segments that were homologous to regions of chromosome 22q11.2, an antigen-responsive hot spot for genetic rearrangements. Many of these short amplicon segments occurred near, between, or in chromosome 22q11.2 Alu sequences. These results suggest that genetic alterations in the 22q11.2 region, possibly induced by exposures to environmental genotoxins during the Persian Gulf War, may have played a role in the pathogenesis of the Gulf War Syndrome. However, the data did not exclude the possibility that other chromosomes also may have been involved. Nonetheless, the detection of polyribonucleotides such as those reported here may have application to the laboratory diagnosis of chronic diseases that have a multifactorial etiology.

The Risk of Birth Defects among Children of Persian Gulf War Veterans

1997 ◽  
Vol 336 (23) ◽  
pp. 1650-1656 ◽  
Author(s):  
David N. Cowan ◽  
Robert F. DeFraites ◽  
Gregory C. Gray ◽  
Mary B. Goldenbaum ◽  
Samuel M. Wishik
Keyword(s):  
Birth Defects ◽  
Persian Gulf ◽  
Gulf War ◽  
Persian Gulf War ◽  
War Veterans ◽  
Gulf War Veterans ◽  
Persian Gulf War Veterans

Visceral and cutaneous hypersensitivity in Persian Gulf war veterans with chronic gastrointestinal symptoms

Pain ◽  
2003 ◽  
Vol 102 (1) ◽  
pp. 79-85 ◽  
Author(s):  
Rebecca C. Dunphy ◽  
Lee Bridgewater ◽  
Donald D. Price ◽  
Michael E. Robinson ◽  
Charles J. Zeilman ◽  
...  
Keyword(s):  
Persian Gulf ◽  
Gastrointestinal Symptoms ◽  
Gulf War ◽  
Persian Gulf War ◽  
War Veterans ◽  
Gulf War Veterans ◽  
Cutaneous Hypersensitivity ◽  
Persian Gulf War Veterans

scholarly journals Self-Reported Health of Persian Gulf War Veterans: A Comparison of Help-Seeking and Randomly Ascertained Cases

2002 ◽  
Vol 167 (9) ◽  
pp. 747-752 ◽  
Author(s):  
Lisa Hull ◽  
Anthony S. David ◽  
Kenneth C. Hyams ◽  
Catherine Unwin ◽  
Simon C. Wessely ◽  
...  
Keyword(s):  
Persian Gulf ◽  
Help Seeking ◽  
Gulf War ◽  
Persian Gulf War ◽  
War Veterans ◽  
Gulf War Veterans ◽  
Reported Health ◽  
Persian Gulf War Veterans
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