Functional Analysis of Heme Regulatory Elements of the Transcriptional Activator Hap1

2000 ◽  
Vol 273 (2) ◽  
pp. 584-591 ◽  
Author(s):  
Thomas Hon ◽  
Angela Hach ◽  
Hee Chul Lee ◽  
Tina Cheng ◽  
Li Zhang
Keyword(s):  
Functional Analysis ◽  
Transcriptional Activator ◽  
Regulatory Elements

Functional analysis of the transcriptional activator XlnR of Penicillium oxalicum

2021 ◽  
Author(s):  
Chengqiang Xia ◽  
Liwei Gao ◽  
Zhonghai Li ◽  
Guodong Liu ◽  
Xin Song
Keyword(s):  
Functional Analysis ◽  
Transcriptional Activator ◽  
Penicillium Oxalicum

Structural and Functional Analysis of MouseMsx1Gene Promoter: Sequence Conservation with HumanMSX1Promoter Points at Potential Regulatory Elements

1998 ◽  
Vol 17 (6) ◽  
pp. 561-572 ◽  
Author(s):  
SAYONARA MARIA DE CARVALHO GONZALEZ ◽  
LOUIS H. FERLAND ◽  
BENOIT ROBERT ◽  
ELIANA ABDELHAY
Keyword(s):  
Functional Analysis ◽  
Promoter Sequence ◽  
Regulatory Elements ◽  
Sequence Conservation

In Silico analysis of CCGAC and CATGTG cis-regulatory elements across genomes reveals their roles in gene regulation under stress

2021 ◽  
Vol 22 ◽  
Author(s):  
Sneha Lata Bhadouriya ◽  
Abhishek Suresh ◽  
Himanshu Gupta ◽  
Sandhya Mehrotra ◽  
Divya Gupta ◽  
...  
Keyword(s):  
Gene Expression ◽  
Functional Analysis ◽  
Heat Stress ◽  
Statistical Analysis ◽  
In Silico Analysis ◽  
Regulatory Elements ◽  
Stress Conditions ◽  
Base Pairs ◽  
Inducible Genes

Background: Plant yield closely depends on its environment and is negatively affected by abiotic stress conditions like drought, salinity, heat, and cold. Analysis of the stress-inducible genes in Arabidopsis has previously shown that CCGAC and CATGTG play a crucial role in controlling the gene expression through the binding of DREB/CBF and NAC TFs under various stress conditions, mainly drought and salinity. Methods: The pattern of these motifs is conserved, which has been analyzed in this study to find the mechanism of gene expression through spacer specificity, inter motif distance preference, functional analysis, and statistical analysis for four different plants, namely Oryza sativa, Triticum aestivum, Arabidopsis thaliana, and Glycine max. Results: The spacer frequency analysis has shown a preference for particular spacer lengths among four genomes. The spacer specificity at all the spacer lengths which predicts dominance of particular base pairs over others, was analyzed to find the preference of the sequences in the flanking region. Functional analysis on stress-regulated genes for saline, osmotic, and heat stress clearly shows that these motif frequencies with inter motif distance (0-30) in the promoter region of Arabidopsis are highest in genes which are upregulated by saline and osmotic stress and downregulated by heat stress. Conclusion: Microarray data were analyzed to confirm the role of both motifs in stress response pathways. Transcription factors seem to prefer larger motif size with repeated CCGAC and CATGTG elements. The common preference for one spacer was further validated through Box and Whisker’s statistical analysis.

Functional Analysis of a Large set of BRCA2 exon 7 Variants Highlights the Predictive Value of Hexamer Scores in Detecting Alterations of Exonic Splicing Regulatory Elements

2013 ◽  
Vol 34 (11) ◽  
pp. 1547-1557 ◽  
Author(s):  
Daniela Di Giacomo ◽  
Pascaline Gaildrat ◽  
Anna Abuli ◽  
Julie Abdat ◽  
Thierry Frébourg ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Predictive Value ◽  
Regulatory Elements ◽  
Large Set ◽  
Splicing Regulatory Elements

scholarly journals Functional analysis of the evolutionarily conserved cis-regulatory elements on the sox17 gene in zebrafish

2009 ◽  
Vol 326 (2) ◽  
pp. 456-470 ◽  
Author(s):  
Tzu-Min Chan ◽  
Chung-Hao Chao ◽  
Horng-Dar Wang ◽  
Yen-Ju Yu ◽  
Chiou-Hwa Yuh
Keyword(s):  
Functional Analysis ◽  
Regulatory Elements ◽  
Evolutionarily Conserved
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