Role of Gastric Mucosal Constitutive and Inducible Nitric Oxide Synthases in the Development of Stress-Induced Gastric Mucosal Lesions in Rats

1997 ◽  
Vol 236 (2) ◽  
pp. 275-279 ◽  
Author(s):  
Keiji Nishida ◽  
Yoshiji Ohta ◽  
Isao Ishiguro
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthases ◽  
Gastric Mucosal Lesions ◽  
Mucosal Lesions ◽  
Inducible Nitric Oxide

scholarly journals Role of neuronal and inducible nitric oxide synthases in the guinea pig ileum myenteric plexus duringin vitroischemia and reperfusion

2013 ◽  
Vol 25 (2) ◽  
pp. e114-e126 ◽  
Author(s):  
C. Giaroni ◽  
S. Marchet ◽  
E. Carpanese ◽  
V. Prandoni ◽  
R. Oldrini ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Guinea Pig ◽  
Myenteric Plexus ◽  
Nitric Oxide Synthases ◽  
Guinea Pig Ileum ◽  
Inducible Nitric Oxide

The Signaling Pathways in Nitric Oxide Production by Neutrophils Exposed to N-nitrosodimethylamine

2018 ◽  
Vol 16 (2) ◽  
pp. 194-199
Author(s):  
Wioletta Ratajczak-Wrona ◽  
Ewa Jablonska
Keyword(s):  
Nitric Oxide ◽  
Signaling Pathways ◽  
Molecular Mechanisms ◽  
Polymorphonuclear Neutrophils ◽  
Microbial Pathogens ◽  
Human Neutrophils ◽  
No Production ◽  
Oxide Synthase ◽  
Inducible Nitric Oxide

Background: Polymorphonuclear neutrophils (PMNs) play a crucial role in the innate immune system’s response to microbial pathogens through the release of reactive nitrogen species, including Nitric Oxide (NO). </P><P> Methods: In neutrophils, NO is produced by the inducible Nitric Oxide Synthase (iNOS), which is regulated by various signaling pathways and transcription factors. N-nitrosodimethylamine (NDMA), a potential human carcinogen, affects immune cells. NDMA plays a major part in the growing incidence of cancers. Thanks to the increasing knowledge on the toxicological role of NDMA, the environmental factors that condition the exposure to this compound, especially its precursors- nitrates arouse wide concern. Results: In this article, we present a detailed summary of the molecular mechanisms of NDMA’s effect on the iNOS-dependent NO production in human neutrophils. Conclusion: This research contributes to a more complete understanding of the mechanisms that explain the changes that occur during nonspecific cellular responses to NDMA toxicity.

Vasculoprotective Role of Inducible Nitric Oxide Synthase at Inflammatory Coronary Lesions Induced by Chronic Treatment With Interleukin-1β in Pigs in Vivo

Circulation ◽  
1997 ◽  
Vol 96 (9) ◽  
pp. 3104-3111 ◽  
Author(s):  
Yoshihiro Fukumoto ◽  
Hiroaki Shimokawa ◽  
Toshiyuki Kozai ◽  
Toshiaki Kadokami ◽  
Kouichi Kuwata ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Inducible Nitric Oxide Synthase ◽  
Chronic Treatment ◽  
Interleukin 1Β ◽  
Coronary Lesions ◽  
Oxide Synthase ◽  
Inducible Nitric Oxide
Sign in / Sign up

Export Citation Format

Share Document