Structural and Functional Characterization of a Second Subfamily Member of the Calcium-Modulated Bovine Rod Outer Segment Membrane Guanylate Cyclase, ROS-GC2

1997 ◽  
Vol 234 (3) ◽  
pp. 666-670 ◽  
Author(s):  
Rafal Goraczniak ◽  
Teresa Duda ◽  
Rameshwar K. Sharma
Keyword(s):  
Guanylate Cyclase ◽  
Outer Segment ◽  
Functional Characterization ◽  
Membrane Guanylate Cyclase ◽  
Rod Outer Segment ◽  
Subfamily Member

scholarly journals Structural and functional characterization of the rod outer segment membrane guanylate cyclase

1994 ◽  
Vol 302 (2) ◽  
pp. 455-461 ◽  
Author(s):  
R M Goraczniak ◽  
T Duda ◽  
A Sitaramayya ◽  
R K Sharma
Keyword(s):  
Cyclic Gmp ◽  
Outer Segment ◽  
Photoreceptor Cell ◽  
Functional Characterization ◽  
Visual Signal ◽  
Membrane Guanylate Cyclase ◽  
Rod Outer Segment ◽  
Vertebrate Photoreceptor ◽  
Hydrolysis Of

In the vertebrate photoreceptor cell, rod outer segment (ROS) is the site of visual signal-transduction process, and a pivotal molecule that regulates this process is cyclic GMP. Cyclic GMP controls the cationic conductance into the ROS, and light causes a decrease in the conductance by activating hydrolysis of the cyclic nucleotide. The identity of the granylate cyclase (ROS-GC) that synthesizes this pool of cyclic GMP is unknown. We now report the cloning, expression and functional characterization of a DNA from bovine retina that encodes ROS-GC.

scholarly journals Impairment of the Rod Outer Segment Membrane Guanylate Cyclase Dimerization in A Cone−Rod Dystrophy Results in Defective Calcium Signaling†

Biochemistry ◽  
2000 ◽  
Vol 39 (41) ◽  
pp. 12522-12533 ◽  
Author(s):  
Teresa Duda ◽  
Venkateswar Venkataraman ◽  
Anna Jankowska ◽  
Christian Lange ◽  
Karl-W. Koch ◽  
...  
Keyword(s):  
Calcium Signaling ◽  
Guanylate Cyclase ◽  
Outer Segment ◽  
Membrane Guanylate Cyclase ◽  
Rod Outer Segment

scholarly journals Calcium-Modulated Rod Outer Segment Membrane Guanylate Cyclase Type 1 Transduction Machinery in the Testes

2006 ◽  
Vol 28 (1) ◽  
pp. 50-58 ◽  
Author(s):  
A. Jankowska ◽  
B. Burczynska ◽  
T. Duda ◽  
J. B. Warchol ◽  
R. K. Sharma
Keyword(s):  
Guanylate Cyclase ◽  
Outer Segment ◽  
Membrane Guanylate Cyclase ◽  
Rod Outer Segment

A novel calcium-dependent activator of retinal rod outer segment membrane guanylate cyclase

Biochemistry ◽  
1995 ◽  
Vol 34 (44) ◽  
pp. 14279-14283 ◽  
Author(s):  
Nikolay Pozdnyakov ◽  
Akiko Yoshida ◽  
Nigel G. F. Cooper ◽  
Alexander Margulis ◽  
Teresa Duda ◽  
...  
Keyword(s):  
Guanylate Cyclase ◽  
Outer Segment ◽  
Membrane Guanylate Cyclase ◽  
Rod Outer Segment ◽  
Calcium Dependent ◽  
Retinal Rod

scholarly journals Regulatory modes of rod outer segment membrane guanylate cyclase differ in catalytic efficiency and Ca2+-sensitivity

2003 ◽  
Vol 270 (18) ◽  
pp. 3814-3821 ◽  
Author(s):  
Ji-Young Hwang ◽  
Christian Lange ◽  
Andreas Helten ◽  
Doris Hoppner-Heitmann ◽  
Teresa Duda ◽  
...  
Keyword(s):  
Guanylate Cyclase ◽  
Outer Segment ◽  
Catalytic Efficiency ◽  
Membrane Guanylate Cyclase ◽  
Rod Outer Segment

Mutations in the Rod Outer Segment Membrane Guanylate Cyclase in a Cone−Rod Dystrophy Cause Defects in Calcium Signaling†

Biochemistry ◽  
1999 ◽  
Vol 38 (42) ◽  
pp. 13912-13919 ◽  
Author(s):  
Teresa Duda ◽  
Anuradha Krishnan ◽  
Venkateswar Venkataraman ◽  
Christian Lange ◽  
Karl-Wilhelm Koch ◽  
...  
Keyword(s):  
Calcium Signaling ◽  
Guanylate Cyclase ◽  
Outer Segment ◽  
Membrane Guanylate Cyclase ◽  
Rod Outer Segment

Structural and Biochemical Identity of Retinal Rod Outer Segment Membrane Guanylate Cyclase

1993 ◽  
Vol 194 (2) ◽  
pp. 855-861 ◽  
Author(s):  
A. Margulis ◽  
R.M. Goraczniak ◽  
T. Duda ◽  
R.K. Sharma ◽  
A. Sitaramayya
Keyword(s):  
Guanylate Cyclase ◽  
Outer Segment ◽  
Membrane Guanylate Cyclase ◽  
Rod Outer Segment ◽  
Retinal Rod
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