Characterization of DNAse I Hypersensitive Sites in the 120-kb 5′ to the CFTR Gene

1995 ◽  
Vol 211 (1) ◽  
pp. 274-281 ◽  
Author(s):  
A.N. Smith ◽  
C.J.C. Wardle ◽  
A. Harris
Keyword(s):  
Dnase I ◽  
Cftr Gene ◽  
Dnase I Hypersensitive Sites ◽  
Hypersensitive Sites

scholarly journals In Vivo Analysis of DNase I Hypersensitive Sites in the Human CFTR Gene

1999 ◽  
Vol 5 (4) ◽  
pp. 211-223 ◽  
Author(s):  
Danielle S. Moulin ◽  
Ania L. Manson ◽  
Hugh N. Nuthall ◽  
David J. Smith ◽  
Clare Huxley ◽  
...  
Keyword(s):  
Dnase I ◽  
Cftr Gene ◽  
Dnase I Hypersensitive Sites ◽  
Hypersensitive Sites ◽  
In Vivo Analysis

Cloning and Characterization of the Mouse Glucokinase Gene Locus and Identification of Distal Liver-Specific DNase I Hypersensitive Sites

Genomics ◽  
1995 ◽  
Vol 29 (3) ◽  
pp. 740-750 ◽  
Author(s):  
CATHERINE POSTIC ◽  
KEVIN D. NISWENDER ◽  
JEAN-FRANCOIS DECAUX ◽  
RAMINE PARSA ◽  
KATHY D. SHELTON ◽  
...  
Keyword(s):  
Gene Locus ◽  
Dnase I ◽  
Glucokinase Gene ◽  
Dnase I Hypersensitive Sites ◽  
Hypersensitive Sites

scholarly journals Evaluation of potential regulatory elements identified as DNase I hypersensitive sites in the CFTR gene

2002 ◽  
Vol 269 (2) ◽  
pp. 553-559 ◽  
Author(s):  
Marios Phylactides ◽  
Rebecca Rowntree ◽  
Hugh Nuthall ◽  
David Ussery ◽  
Ann Wheeler ◽  
...  
Keyword(s):  
Regulatory Elements ◽  
Dnase I ◽  
Cftr Gene ◽  
Dnase I Hypersensitive Sites ◽  
Hypersensitive Sites

scholarly journals Genome-Wide Characterization of DNase I-Hypersensitive Sites and Cold Response Regulatory Landscapes in Grasses

2020 ◽  
Vol 32 (8) ◽  
pp. 2457-2473 ◽  
Author(s):  
Jinlei Han ◽  
Pengxi Wang ◽  
Qiongli Wang ◽  
Qingfang Lin ◽  
Zhiyong Chen ◽  
...  
Keyword(s):  
Dnase I ◽  
Cold Response ◽  
Dnase I Hypersensitive Sites ◽  
Genome Wide ◽  
Hypersensitive Sites ◽  
Regulatory Landscapes

scholarly journals Analysis of DNase-I-hypersensitive sites at the 3′ end of the cystic fibrosis transmembrane conductance regulator gene (CFTR)

1999 ◽  
Vol 341 (3) ◽  
pp. 601-611 ◽  
Author(s):  
Hugh N. NUTHALL ◽  
Danielle S. MOULIN ◽  
Clare HUXLEY ◽  
Ann HARRIS
Keyword(s):  
Cystic Fibrosis ◽  
Regulatory Element ◽  
Dnase I ◽  
Cftr Gene ◽  
Transmembrane Conductance Regulator ◽  
Regulator Gene ◽  
Transmembrane Conductance ◽  
Dnase I Hypersensitive Sites ◽  
Hypersensitive Sites ◽  
Cystic Fibrosis Transmembrane

The cystic fibrosis transmembrane conductance regulator gene (CFTR) exhibits a complex pattern of expression that shows temporal and spatial regulation, although the control mechanisms are not fully known. We have mapped DNase-I-hypersensitive sites (DHSs) flanking the CFTR gene with the aim of identifying potential regulatory elements. We previously characterized DHSs at -79.5 and -20.9 kb with respect to the CFTR translational start site and a regulatory element in the first intron of the gene at 185+10 kb. We have now mapped five DHSs lying 3′ to the CFTR gene at 4574+5.4, +6.8, +7.0, +7.4 and +15.6 kb that show some degree of tissue specificity. The DHSs are seen in chromatin extracted from human primary epithelial cells and cell lines; the presence of the +15.6 kb site is tissue-specific in transgenic mice carrying a human CFTR yeast artificial chromosome. Further analysis of the 4574+15.6 kb DHS implicates the involvement of CCAAT-enhancer-binding protein (C/EBP), cAMP-response-element-binding protein (CREB)/activating transcription factor (ATF) and activator protein 1 (AP-1) family transcription factors at this regulatory element.

scholarly journals Mapping and Characterization of DNase I Hypersensitive Sites in Arabidopsis Chromatin

2007 ◽  
Vol 48 (3) ◽  
pp. 459-470 ◽  
Author(s):  
Y. Kodama ◽  
S. Nagaya ◽  
A. Shinmyo ◽  
K. Kato
Keyword(s):  
Dnase I ◽  
Dnase I Hypersensitive Sites ◽  
Hypersensitive Sites

Characterization of DNase I hypersensitive sites in the mouse 68-kDa neurofilament gene

1996 ◽  
Vol 21 (6) ◽  
pp. 713-722 ◽  
Author(s):  
Robert Kure ◽  
Tina R. Ivanov ◽  
Ian R. Brown
Keyword(s):  
Dnase I ◽  
Dnase I Hypersensitive Sites ◽  
Hypersensitive Sites

The prediction of human DNase I hypersensitive sites based on DNA sequence information

2021 ◽  
Vol 209 ◽  
pp. 104223
Author(s):  
Wei Su ◽  
Fang Wang ◽  
Jiu-Xin Tan ◽  
Fu-Ying Dao ◽  
Hui Yang ◽  
...  
Keyword(s):  
Dna Sequence ◽  
Dnase I ◽  
Sequence Information ◽  
Dnase I Hypersensitive Sites ◽  
Hypersensitive Sites
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