Effect of Activation of the Serotoninergic System During Prolonged Starvation on Subsequent Caloric Intake and Macronutrient Selection in the Zucker Rat

Appetite ◽  
1993 ◽  
Vol 20 (2) ◽  
pp. 135-144 ◽  
Author(s):  
J. Duhault ◽  
F. Lacour ◽  
J. Espinal ◽  
Y. Rolland
Keyword(s):  
Caloric Intake ◽  
Serotoninergic System ◽  
Zucker Rat ◽  
Prolonged Starvation ◽  
Macronutrient Selection

Protein appetite is increased after central leptin-induced fat depletion

2007 ◽  
Vol 293 (4) ◽  
pp. R1468-R1473 ◽  
Author(s):  
Michael F. Wiater ◽  
Bryan D. Hudson ◽  
Yvette Virgin ◽  
Sue Ritter
Keyword(s):  
Body Weight ◽  
Food Intake ◽  
Body Fat ◽  
Caloric Intake ◽  
Sprague Dawley ◽  
Body Protein ◽  
Macronutrient Selection ◽  
Daily Diet ◽  
Nadir Point ◽  
And Control

Leptin reduces body fat selectively, sparing body protein. Accordingly, during chronic leptin administration, food intake is suppressed, and body weight is reduced until body fat is depleted. Body weight then stabilizes at this fat-depleted nadir, while food intake returns to normal caloric levels, presumably in defense of energy and nutritional homeostasis. This model of leptin treatment offers the opportunity to examine controls of food intake that are independent of leptin's actions, and provides a window for examining the nature of feeding controls in a “fatless” animal. Here we evaluate macronutrient selection during this fat-depleted phase of leptin treatment. Adult, male Sprague-Dawley rats were maintained on standard pelleted rodent chow and given daily lateral ventricular injections of leptin or vehicle solution until body weight reached the nadir point and food intake returned to normal levels. Injections were then continued for 8 days, during which rats self-selected their daily diet from separate sources of carbohydrate, protein, and fat. Macronutrient choice differed profoundly in leptin and control rats. Leptin rats exhibited a dramatic increase in protein intake, whereas controls exhibited a strong carbohydrate preference. Fat intake did not differ between groups at any time during the 8-day test. Despite these dramatic differences in macronutrient selection, total daily caloric intake did not differ between groups except on day 2. Thus controls of food intake related to ongoing metabolic and nutritional requirements may supersede the negative feedback signals related to body fat stores.

Effect of morphine on caloric intake and macronutrient selection in male and female Lou/c/jall rats during ageing

2001 ◽  
Vol 122 (15) ◽  
pp. 1825-1839 ◽  
Author(s):  
Stéphane Boghossian ◽  
Didier Jourdan ◽  
Matthieu Dacher ◽  
Josette Alliot
Keyword(s):  
Caloric Intake ◽  
Male And Female ◽  
Macronutrient Selection

Amygdaloid-lesion hyperphagia: impaired response to caloric challenges and altered macronutrient selection

1998 ◽  
Vol 275 (2) ◽  
pp. R485-R493 ◽  
Author(s):  
Bruce M. King ◽  
Kirk N. Rossiter ◽  
Samuel G. Stines ◽  
Gelana M. Zaharan ◽  
Jack T. Cook ◽  
...  
Keyword(s):  
Food Intake ◽  
High Fat Diet ◽  
Caloric Intake ◽  
Female Rats ◽  
High Fat ◽  
Carbohydrate Diet ◽  
High Carbohydrate ◽  
Macronutrient Selection ◽  
Daily Food ◽  
Selection Of

Lesions of the most posterodorsal aspects of the amygdala in female rats result in hyperphagia and moderate obesity. In the present study, rats with amygdaloid lesions did not increase their daily food intake when their powdered diet was diluted with 25 or 50% nonnutritive bulk. Control animals adjusted their food intake appropriately. In a second study, rats with lesions ate less food (lab chow pellets) than controls when allowed to eat for only 1 h/day for 10 days. In experiment 3, rats were offered a three-choice macronutrient diet. Whereas four of six control animals preferred the high-fat diet, all eight of the rats with amygdaloid lesions displayed a distinct preference for the high-carbohydrate diet, including those that had preferred the high-fat diet before surgery. These results, along with the previous finding that identical lesions result in hyperinsulinemia, indicate that the amygdala is involved in both the homeostatic regulation of food (caloric) intake and the selection of macronutrients.

Morphometric analysis of peroxisomes in hepatocytes of alcohol-fed rats

1989 ◽  
Vol 47 ◽  
pp. 1100-1101
Author(s):  
D.C. Dominguez ◽  
J.T. Ellzey
Keyword(s):  
Caloric Intake ◽  
Volume Density ◽  
Controlled Study ◽  
Control Group ◽  
Numerical Density ◽  
Cacodylate Buffer ◽  
Paired Control ◽  
Experimental Group ◽  
Liver Peroxisomes ◽  
Single Lesion

Peroxisomes which participate in 1ipid metabolism have been shown to be altered in several metabolic disorders and toxic conditions. In alcoholic liver disease, the single lesion most frequently found is lipid accumu1ation in hepatocytes. However, the mechanisms for this 1ipid accumu1ation are not clear. The occurrence of modifications of liver peroxisomes due to excess alcohol consumption has not been subjected to a controlled study. We utilized a combination of cytochemica1 and morphometrictechniques to study the size and number of liver peroxisomes in rats fed an alcohol-supplemented diet compared to those of matched-paired control animals.Male Sprague-Daw1ey rats (400-500 g) received a liquid diet. The experimental group (N = 5/group) was fed a diet containing 30% ethanol-derived calories (EDC) and the control group was fed an isocaloric diet to 30% EDC. A pair feeding procedure was employed to control for caloric intake. Small pieces of liver randomly selected, were fixed in 2.3% -glutaraldehyde in 0.1 M sodium cacodylate buffer, pH 7.2, incubated in a DAB medium and postfixed with. 2% aqueous osmium tetroxide. EM photographs were taken from sections of 3 tissue blocks from each sample (7,200X) with a Zeiss EM10-A (60 kV). With the use of a point counting method and a digital planimeter the volume density (Vv) and numerical density (Nv) were determined.

Characterization of hepatobiliary organic anion transporter regulation in the Zucker rat

2004 ◽  
Vol 42 (08) ◽  
Author(s):  
A Geier ◽  
CG Dietrich ◽  
C Gartung ◽  
F Lammert ◽  
HE Wasmuth ◽  
...  
Keyword(s):  
Organic Anion ◽  
Organic Anion Transporter ◽  
Zucker Rat ◽  
Anion Transporter

The Effects of Reproductive Status and Water Temperature on the Caloric Intake of Tursiops truncatus

2020 ◽  
Vol 46 (4) ◽  
pp. 382-394
Author(s):  
Holli C. Eskelinen ◽  
Jill L. Richardson ◽  
Juliana K. Wendt
Keyword(s):  
Water Temperature ◽  
Tursiops Truncatus ◽  
Caloric Intake ◽  
Reproductive Status

754-P: Full-Fat and Low-Fat Dairy, within the Same Caloric Intake, Have Similar Impact on A1C and Cardiovascular Risk Factors: A Randomized Controlled Study

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 754-P
Author(s):  
JOANNA MITRI ◽  
SHAHEEN TOMAH ◽  
ADHAM MOTTALIB ◽  
VERONICA SALSBERG ◽  
SAHAR ASHRAFZADEH ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Caloric Intake ◽  
Randomized Controlled Study ◽  
Controlled Study ◽  
Low Fat ◽  
Randomized Controlled
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