Importance of Amino Acid Residue 474 for Substrate Specificity of Canine and Human Cytochrome P450 3A Enzymes

2001 ◽  
Vol 389 (2) ◽  
pp. 264-270 ◽  
Author(s):  
You-Qun He ◽  
Fabienne Roussel ◽  
James R. Halpert
Keyword(s):  
Cytochrome P450 ◽  
Amino Acid ◽  
Substrate Specificity ◽  
Amino Acid Residue ◽  
Cytochrome P450 3A ◽  
Human Cytochrome

scholarly journals Kinetic characterization of yeast alcohol dehydrogenases. Amino acid residue 294 and substrate specificity.

1987 ◽  
Vol 262 (8) ◽  
pp. 3754-3761
Author(s):  
A.J. Ganzhorn ◽  
D.W. Green ◽  
A.D. Hershey ◽  
R.M. Gould ◽  
B.V. Plapp
Keyword(s):  
Amino Acid ◽  
Substrate Specificity ◽  
Amino Acid Residue ◽  
Kinetic Characterization ◽  
Alcohol Dehydrogenases

Prediction of amino acid residues participated in substrate recognition by cytochrome P450 subfamilies with broad substrate specificity

2013 ◽  
Vol 26 (2) ◽  
pp. 86-91 ◽  
Author(s):  
Maria S. Zharkova ◽  
Boris N. Sobolev ◽  
Nina Yu. Oparina ◽  
Alexander V. Veselovsky ◽  
Alexander I. Archakov
Keyword(s):  
Cytochrome P450 ◽  
Amino Acid ◽  
Substrate Specificity ◽  
Substrate Recognition ◽  
Amino Acid Residues ◽  
Broad Substrate Specificity

Amino Acid Residues Affecting the Activities of Human Cytochrome P450 2C9 and 2C19

2002 ◽  
Vol 30 (8) ◽  
pp. 931-936 ◽  
Author(s):  
Toshiro Niwa ◽  
Akira Kageyama ◽  
Kae Kishimoto ◽  
Yoshiyasu Yabusaki ◽  
Fumihide Ishibashi ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Amino Acid ◽  
Amino Acid Residues ◽  
Cytochrome P450 2C9 ◽  
Human Cytochrome

scholarly journals The crystal structure of a xyloglucan-specific endo-β-1,4-glucanase from Geotrichum sp. M128 xyloglucanase reveals a key amino acid residue for substrate specificity

FEBS Journal ◽  
2009 ◽  
Vol 276 (18) ◽  
pp. 5094-5100 ◽  
Author(s):  
Katsuro Yaoi ◽  
Hidemasa Kondo ◽  
Ayako Hiyoshi ◽  
Natsuko Noro ◽  
Hiroshi Sugimoto ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Amino Acid ◽  
Substrate Specificity ◽  
Amino Acid Residue

Mechanism-based inhibition of human Cytochrome P450-3A activity by grapefruit hybrids having low furanocoumarin content

Xenobiotica ◽  
2012 ◽  
Vol 42 (12) ◽  
pp. 1163-1169 ◽  
Author(s):  
David J. Greenblatt ◽  
Yanli Zhao ◽  
Michael J. Hanley ◽  
Chunxian Chen ◽  
Jerold S. Harmatz ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 3A ◽  
Human Cytochrome
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