Selective Changes in Protein Kinase C Isoforms and Phosphorylation of Endogenous Substrate Proteins in Rat Cerebral Cortex during Pre- and Postnatal Ethanol Exposure

1998 ◽  
Vol 356 (2) ◽  
pp. 249-257 ◽  
Author(s):  
Kalyankar Mahadev ◽  
Mohan C. Vemuri
Keyword(s):  
Cerebral Cortex ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Ethanol Exposure ◽  
Rat Cerebral Cortex ◽  
Kinase C ◽  
Endogenous Substrate ◽  
Substrate Proteins ◽  
Protein Kinase C Isoforms

Differential activation of protein kinase C isoforms following chemical ischemia in rat cerebral cortex slices

2006 ◽  
Vol 49 (8) ◽  
pp. 729-736 ◽  
Author(s):  
Rita Selvatici ◽  
Sofia Falzarano ◽  
Lara Franceschetti ◽  
Sabrina Cavallini ◽  
Silvia Marino ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Rat Cerebral Cortex ◽  
Differential Activation ◽  
Kinase C ◽  
Cortex Slices ◽  
Protein Kinase C Isoforms

Protein kinase C activity, translocation, and selective isoform subcellular redistribution in the rat cerebral cortex after in vitro ischemia

2002 ◽  
Vol 71 (1) ◽  
pp. 64-71 ◽  
Author(s):  
Rita Selvatici ◽  
Silvia Marino ◽  
Carmela Piubello ◽  
Donata Rodi ◽  
Lorenzo Beani ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Rat Cerebral Cortex ◽  
In Vitro Ischemia ◽  
Kinase C ◽  
Protein Kinase C Activity

scholarly journals Localization of non-conventional protein kinase C isoforms in bovine brain cell nuclei

1995 ◽  
Vol 305 (1) ◽  
pp. 269-275 ◽  
Author(s):  
U Rosenberger ◽  
M Shakibaei ◽  
K Buchner
Keyword(s):  
Cerebral Cortex ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Nuclear Envelope ◽  
Immunofluorescence Microscopy ◽  
Brain Cell ◽  
Bovine Brain ◽  
Cell Nuclei ◽  
Kinase C ◽  
Protein Kinase C Isoforms

Using Western blotting and immunofluorescence microscopy we detected the protein kinase C isoforms delta, epsilon and zeta in isolated cell nuclei from bovine cerebral cortex. Both protein kinase C (PKC) delta and PKC epsilon are present in higher concentrations in neuronal than in glial nuclei and are located inside the nucleus and at the nuclear envelope. There they give a punctate staining in immunofluorescence microscopy. PKC zeta is also present both in the nucleoplasm and at the nuclear envelope. PKC eta could not be detected in the cell nuclei and, even in the homogenate of cerebral cortex, this isoform is present only in very low concentrations. The antibody against PKC eta bound strongly to a nucleoplasmic protein with an apparent molecular mass of 99 kDa. The localization of non-conventional PKC isoforms at the cell nucleus strongly indicates that these isoforms are directly involved in the regulation of nuclear processes.

Modulation of protein kinase C isoforms by PAF in cerebral cortex☆

1999 ◽  
Vol 58 (1) ◽  
pp. 19-27 ◽  
Author(s):  
M.C Calcerrada ◽  
M.J Pérez–Alvarez ◽  
R.E Catalán ◽  
A.M Martı́nez
Keyword(s):  
Cerebral Cortex ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Kinase C ◽  
Protein Kinase C Isoforms

Variation in the expression of the mRNA for protein kinase C isoforms in the rat suprachiasmatic nuclei, caudate putamen and cerebral cortex

1998 ◽  
Vol 53 (1-2) ◽  
pp. 277-284 ◽  
Author(s):  
Felino Ramon A Cagampang ◽  
Marcus Rattray ◽  
Iain C Campbell ◽  
John F Powell ◽  
Clive W Coen
Keyword(s):  
Cerebral Cortex ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Suprachiasmatic Nuclei ◽  
Caudate Putamen ◽  
Kinase C ◽  
Protein Kinase C Isoforms
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