Characterization of a Silencer Regulatory Element in the Rat PAP I Gene Which Confers Tissue-Specific Expression and Is Promoter-Dependent

1997 ◽  
Vol 340 (1) ◽  
pp. 111-116 ◽  
Author(s):  
Emilia M. Ortiz ◽  
Nelson J. Dusetti ◽  
Jean-Charles Dagorn ◽  
Juan L. Iovanna
Keyword(s):  
Regulatory Element ◽  
Specific Expression ◽  
Tissue Specific ◽  
Tissue Specific Expression ◽  
I Gene

scholarly journals Tissue-specific expression of apolipoprotein A-I (ApoA-I) is regulated by the 5′-flanking region of the human ApoA-I gene.

1988 ◽  
Vol 263 (34) ◽  
pp. 18530-18536 ◽  
Author(s):  
K Higuchi ◽  
S W Law ◽  
J M Hoeg ◽  
U K Schumacher ◽  
N Meglin ◽  
...  
Keyword(s):  
Specific Expression ◽  
Tissue Specific ◽  
Tissue Specific Expression ◽  
Apolipoprotein A ◽  
Flanking Region ◽  
I Gene

Characterization of microRNAs from neem (Azadirachta indica) and their tissue-specific expression study in leaves and stem

3 Biotech ◽  
2021 ◽  
Vol 11 (6) ◽  
Author(s):  
Sujay Paul ◽  
Paula Reyes-Pérez ◽  
Paola Isabel Angulo-Bejarano ◽  
Aashish Srivastava ◽  
Sathishkumar Ramalingam ◽  
...  
Keyword(s):  
Azadirachta Indica ◽  
Expression Study ◽  
Specific Expression ◽  
Tissue Specific ◽  
Tissue Specific Expression

Characterization of G3BPs: Tissue specific expression, chromosomal localisation andrasGAP120 binding studies

2001 ◽  
Vol 84 (1) ◽  
pp. 173-187 ◽  
Author(s):  
Derek Kennedy ◽  
Juliet French ◽  
Estelle Guitard ◽  
Kelin Ru ◽  
Bruno Tocque ◽  
...  
Keyword(s):  
Binding Studies ◽  
Specific Expression ◽  
Tissue Specific ◽  
Tissue Specific Expression ◽  
Chromosomal Localisation

Tissue-specific expression of the rat pancreatic elastase I gene in transgenic mice

Cell ◽  
1984 ◽  
Vol 38 (3) ◽  
pp. 639-646 ◽  
Author(s):  
Galvin H. Swift ◽  
Robert E. Hammer ◽  
Raymond J. MacDonald ◽  
Ralph L. Brinster
Keyword(s):  
Transgenic Mice ◽  
Specific Expression ◽  
Tissue Specific ◽  
Pancreatic Elastase ◽  
Tissue Specific Expression ◽  
I Gene

scholarly journals Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells

2019 ◽  
Vol 203 (3) ◽  
pp. 686-695 ◽  
Author(s):  
Brian M. Larsen ◽  
Jennifer E. Cowan ◽  
Yueqiang Wang ◽  
Yu Tanaka ◽  
Yongge Zhao ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Regulatory Element ◽  
Thymic Epithelial Cells ◽  
Specific Expression ◽  
Tissue Specific ◽  
Tissue Specific Expression

scholarly journals Human leukocyte antigen F (HLA-F). An expressed HLA gene composed of a class I coding sequence linked to a novel transcribed repetitive element.

1990 ◽  
Vol 171 (1) ◽  
pp. 1-18 ◽  
Author(s):  
D E Geraghty ◽  
X H Wei ◽  
H T Orr ◽  
B H Koller
Keyword(s):  
Dna Sequence ◽  
Hla Class I ◽  
Class I ◽  
Northern Analysis ◽  
Protein Sequence Analysis ◽  
Specific Expression ◽  
Rnase Protection ◽  
Tissue Specific ◽  
Tissue Specific Expression ◽  
I Gene

We describe here the isolation and sequencing of a previously uncharacterized HLA class I gene. This gene, HLA-5.4, is the third non-HLA-A,B,C gene characterized whose sequence shows it encodes an intact class I protein. RNase protection assays with a probe specific for this gene demonstrated its expression in B lymphoblastoid cell lines, in resting T cells, and skin cells, while no mRNA could be detected in the T cell line Molt 4. Consistent with a pattern of expression different from that of other class I genes, DNA sequence comparisons identified potential regulator motifs unique to HLA-5.4 and possibly essential for tissue-specific expression. Protein sequence analysis of human and murine class I antigens has identified 10 highly conserved residues believed to be involved in antigen binding. Five of these are altered in HLA-5.4, and of these, three are nonconservative. In addition, examination of the HLA-5.4 DNA sequence predicts that the cytoplasmic segment of this protein is shorter than that of the classical transplantation antigens. The 3' untranslated region of the HLA-5.4 gene contains one member of a previously undescribed multigene family consisting of at least 30 members. Northern analysis showed that several of these sequences were transcribed, and the most ubiquitous transcript, a 600-nucleotide polyadenylated mRNA, was found in all tissues and cells examined. This sequence is conserved in the mouse genome, where a similar number of copies were found, and one of these sequences was also transcribed, yielding a 600-nucleotide mRNA. The characterization of this unique HLA class I gene and the demonstration of its tissue-specific expression have prompted us to propose that HLA-5.4 be designated HLA-F.

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