Differential Expression of the Murine Eukaryotic Translation Initiation Factor Isogenes eIF4AIand eIF4AIIIs Dependent upon Cellular Growth Status

1997 ◽  
Vol 338 (1) ◽  
pp. 111-120 ◽  
Author(s):  
D.M. Williams-Hill ◽  
R.F. Duncan ◽  
P.J. Nielsen ◽  
S.M. Tahara
Keyword(s):  
Differential Expression ◽  
Translation Initiation ◽  
Translation Initiation Factor ◽  
Cellular Growth ◽  
Initiation Factor ◽  
Eukaryotic Translation Initiation Factor ◽  
Eukaryotic Translation ◽  
Growth Status ◽  
Eukaryotic Translation Initiation

scholarly journals Differential expression of the eukaryotic translation initiation factor EIF1B in the brain metastases of patients with breast cancer.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Breast Cancer ◽  
Brain Metastases ◽  
Differential Expression ◽  
Translation Initiation ◽  
Translation Initiation Factor ◽  
Initiation Factor ◽  
Eukaryotic Translation Initiation Factor ◽  
Eukaryotic Translation ◽  
Eukaryotic Translation Initiation ◽  
The Brain

Metastasis to the brain is a complication of breast cancer (1, 2) with limited treatment options (3). We mined published microarray data (4, 5) to discover genes associated with brain metastases in patients with metastatic breast cancer. We identified significant differential expression of the eukaryotic translation initiation factor EIF1B in the brain metastases of patients with breast cancer as compared to primary tumors of the breast. EIF1B may be relevant to the underlying biology by which tumor cells of the breast spread to the brain.

Sign in / Sign up

Export Citation Format

Share Document