Metal Complexes with Biologically Important Ligands. CLXVI Tetracarbonyl Complexes of Chromium(0) and Molybdenum(0) with Schiff Bases from Pyridine-2-carboxaldehyde and α-Amino Acid Esters as N,N-Chelate Ligands

2007 ◽  
Vol 633 (2) ◽  
pp. 235-238 ◽  
Author(s):  
Theodor Ederer ◽  
Richard S. Herrick ◽  
Wolfgang Beck
Keyword(s):  
Amino Acid ◽  
Metal Complexes ◽  
Schiff Bases ◽  
Amino Acid Esters ◽  
Chelate Ligands ◽  
Acid Esters

Metallkomplexe mit biologisch wichtigen Liganden, CXV. Addition von α-Aminosäureestern an [CpFe(CO)3]+: Carbamoylkomplexe Cp(OC)2Fe-C(O)NHCHRCO2R’ und Kristallstruktur von Cp(OC)2Fe-C(O)NHCH2CO2Et / Metal Complexes of Biologically Important Ligands, CXV. Addition of α-Amino Acid Esters to [CpFe(CO)3]+: Carbamoyl Complexes Cp(OC)2Fe-C(O)NHCHRCO2R' and Crystal Structure of Cp(OC)2Fe-C(O)NHCH2CO2Et

1999 ◽  
Vol 54 (3) ◽  
pp. 385-388 ◽  
Author(s):  
Reinhold Urban ◽  
Kurt Polbom ◽  
Wolfgang Beck
Keyword(s):  
Crystal Structure ◽  
Amino Acid ◽  
Metal Complexes ◽  
Amino Acid Esters ◽  
X Ray Diffraction ◽  
Carbonyl Ligand ◽  
X Ray ◽  
Acid Esters

α-Amino acid esters can be added to a carbonyl ligand of [CpFe(CO)3]+CF3SO3- to give the carbamoyl complexes Cp(OC)2Fe-C(O)NHCHRCO2R′ (R = H, Me, CHMe2, CH2Ph; R′ = Et, Me). This type of reaction may be useful for the marking of peptides at the amino end. The crystal structure of Cp(OC)2Fe-C(O)NHCH2CO2Et was determined by X-ray diffraction.

Metallkomplexe von Biologisch Wichtigen Liganden, CXLVIII [1]. Katalytische Peptidsynthese aus Glycinester miit Hilfe von Triflaten Und Cloriden der Seltenen Erden, sowie von Metall(III), (IV), (V) und (VI)-Chloriden / Metal Complexes of Biologically Important Ligands, CXLVIII [1]. Synthesis of Peptides from Glycine Ester Catalysed by Triflates and Chlorides of Metal(III, IV, V And VI) Ions

2003 ◽  
Vol 58 (1) ◽  
pp. 85-91 ◽  
Author(s):  
Jan Schapp ◽  
Wolfgang Beck
Keyword(s):  
Amino Acid ◽  
Metal Complexes ◽  
Dansyl Chloride ◽  
Amino Acid Esters ◽  
Metal Chlorides ◽  
Peptide Formation ◽  
Metal Triflates ◽  
High Yields ◽  
Acid Esters

Abstract Formation of di- and triglycine ethylester which were determined by HPLC after derivatisation with dansyl chloride was observed in medium to high yields from CH2Cl2 solutions of glycine ethylester in the presence of metal triflates and metal chlorides: FeCl3 (yield 82%), AlCl3 (73%), GdCl3 (56%), La(OTf)3 (59%), Sc(OTf)3 (55%), ZrCl4 (62%), HfCl4 (60%), VOCl3 (43%), TaCl5 (29%). Esters of higher α-amino acid esters (AlaOMe, PheOMe) gave lower yields in peptide formation.

Synthesis and infrared spectra of some transition metal complexes of α-amino acid esters

1967 ◽  
Vol 20 (4) ◽  
pp. 675 ◽  
Author(s):  
RW Hay ◽  
LJ Porter
Keyword(s):  
Amino Acid ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Infrared Spectra ◽  
Metal Ion ◽  
Amino Acid Esters ◽  
Visible Spectra ◽  
Metal Ratio ◽  
Acid Esters

A variety of transition metal complexes of a-amino acid esters have been synthesized, and characterized by analysis, conductivity measurements, and infrared spectra. The complexes can be broadly divided into two groups: (a) complexes in which only a metal-nitrogen bond occurs with the α-amino group of the ester, and (b) complexes in which chelate ring formation occurs via secondary donor groups on the ligand. These latter complexes are found with methyl L-histidinate, methyl γ-glutamate, and methyl L-cysteinate. With the exception of a methyl tryptophanate complex, the infrared spectra show that there is no interaction between the carbonyl group of the ester and the metal ion. The visible spectra of aqueous solutions of the esters and copper(II) at a ligand/metal ratio of 5 : 1 have maxima in the 600-650 mμ range at pH 7 consistent with copper-nitrogen bonding only.

Sign in / Sign up

Export Citation Format

Share Document