Homologous chromosome pairing inSchizosaccharomyces pombe

Yeast ◽  
2006 ◽  
Vol 23 (13) ◽  
pp. 977-989 ◽  
Author(s):  
Jennifer L. Wells ◽  
David W. Pryce ◽  
Ramsay J. McFarlane
Keyword(s):  
Chromosome Pairing ◽  
Homologous Chromosome ◽  
Homologous Chromosome Pairing

Non-homologous chromosome pairing during meiosis in haploid Brassica rapa

2021 ◽  
Author(s):  
Jiachen Yuan ◽  
Gongyao Shi ◽  
Yan Yang ◽  
Janeen Braynen ◽  
Xinjie Shi ◽  
...  
Keyword(s):  
Brassica Rapa ◽  
Chromosome Pairing ◽  
Homologous Chromosome ◽  
Homologous Chromosome Pairing

scholarly journals Regulating chromosomal movement by the cochaperone FKB-6 ensures timely pairing and synapsis

2017 ◽  
Vol 216 (2) ◽  
pp. 393-408 ◽  
Author(s):  
Benjamin Alleva ◽  
Nathan Balukoff ◽  
Amy Peiper ◽  
Sarit Smolikove
Keyword(s):  
Nuclear Envelope ◽  
Chromosome Pairing ◽  
Meiotic Prophase ◽  
Homologous Chromosome ◽  
Strand Break ◽  
Crossing Over ◽  
Chromosome Movement ◽  
Microtubule Network ◽  
Homologous Chromosome Pairing ◽  
Proper Movement

In meiotic prophase I, homologous chromosome pairing is promoted through chromosome movement mediated by nuclear envelope proteins, microtubules, and dynein. After proper homologue pairing has been established, the synaptonemal complex (SC) assembles along the paired homologues, stabilizing their interaction and allowing for crossing over to occur. Previous studies have shown that perturbing chromosome movement leads to pairing defects and SC polycomplex formation. We show that FKB-6 plays a role in SC assembly and is required for timely pairing and proper double-strand break repair kinetics. FKB-6 localizes outside the nucleus, and in its absence, the microtubule network is altered. FKB-6 is required for proper movement of dynein, increasing resting time between movements. Attenuating chromosomal movement in fkb-6 mutants partially restores the defects in synapsis, in agreement with FKB-6 acting by decreasing chromosomal movement. Therefore, we suggest that FKB-6 plays a role in regulating dynein movement by preventing excess chromosome movement, which is essential for proper SC assembly and homologous chromosome pairing.

A cohesin-based structural platform supporting homologous chromosome pairing in meiosis

2016 ◽  
Vol 62 (3) ◽  
pp. 499-502 ◽  
Author(s):  
Da-Qiao Ding ◽  
Tokuko Haraguchi ◽  
Yasushi Hiraoka
Keyword(s):  
Chromosome Pairing ◽  
Homologous Chromosome ◽  
Homologous Chromosome Pairing

Homologous chromosome pairing in meiosis of higher eukaryotes—still an enigma?

Genome ◽  
2020 ◽  
Vol 63 (10) ◽  
pp. 469-482
Author(s):  
J. Sybenga
Keyword(s):  
Chromosome Pairing ◽  
Dna Sequences ◽  
Homologous Chromosome ◽  
Homology Search ◽  
Size Difference ◽  
Primary Role ◽  
Dna Double Strand Breaks ◽  
Homologous Chromosome Pairing ◽  
Higher Eukaryotes

Meiosis is the basis of the generative reproduction of eukaryotes. The crucial first step is homologous chromosome pairing. In higher eukaryotes, micrometer-scale chromosomes, micrometer distances apart, are brought together by nanometer DNA sequences, at least a factor of 1000 size difference. Models of homology search, homologue movement, and pairing at the DNA level in higher eukaryotes are primarily based on studies with yeast where the emphasis is on the induction and repair of DNA double-strand breaks (DSB). For such a model, the very large nuclei of most plants and animals present serious problems. Homology search without DSBs cannot be explained by models based on DSB repair. The movement of homologues to meet each other and make contact at the molecular level is not understood. These problems are discussed and the conclusion is that at present practically nothing is known of meiotic homologue pairing in higher eukaryotes up to the formation of the synaptonemal complex, and that new, necessarily speculative models must be developed. Arguments are given that RNA plays a central role in homology search and a tentative model involving RNA in homology search is presented. A role of actin in homologue movement is proposed. The primary role of DSBs in higher eukaryotes is concluded to not be in pairing but in the preparation of Holliday junctions, ultimately leading to chromatid exchange.

OsSPO11-1 is essential for both homologous chromosome pairing and crossover formation in rice

Chromosoma ◽  
2010 ◽  
Vol 119 (6) ◽  
pp. 625-636 ◽  
Author(s):  
Hengxiu Yu ◽  
Mo Wang ◽  
Ding Tang ◽  
Kejian Wang ◽  
Fuli Chen ◽  
...  
Keyword(s):  
Chromosome Pairing ◽  
Homologous Chromosome ◽  
Homologous Chromosome Pairing

scholarly journals The Dynamics of Homologous Chromosome Pairing during Male Drosophila Meiosis

2002 ◽  
Vol 12 (17) ◽  
pp. 1473-1483 ◽  
Author(s):  
Julio Vazquez ◽  
Andrew S Belmont ◽  
John W Sedat
Keyword(s):  
Chromosome Pairing ◽  
Homologous Chromosome ◽  
Homologous Chromosome Pairing
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