scholarly journals Renal clearable noble metal nanoparticles: photoluminescence, elimination, and biomedical applications

2017 ◽  
Vol 9 (5) ◽  
pp. e1453 ◽  
Author(s):  
Jing Xu ◽  
Chuanqi Peng ◽  
Mengxiao Yu ◽  
Jie Zheng
Keyword(s):  
Metal Nanoparticles ◽  
Noble Metal ◽  
Biomedical Applications ◽  
Noble Metal Nanoparticles

Role of organic functionalities linked to alkoxysilane precursors in nanomaterials synthesis and their biomedical applications

2015 ◽  
Vol 1719 ◽  
Author(s):  
P. C. Pandey ◽  
Govind Pandey
Keyword(s):  
Salt Tolerance ◽  
Metal Ions ◽  
Metal Nanoparticles ◽  
Noble Metal ◽  
Biomedical Applications ◽  
Ph Sensitivity ◽  
Noble Metal Nanoparticles ◽  
Biological Interactions ◽  
Wide Range

ABSTRACTThe synthesis of biocompatible noble metal nanoparticles dispersible in a wide range of biological media with control of polycrystalinity and nanogeometry, pH sensitivity and salt tolerance has been a challenging requirements. The role of 3-aminopropyltrimethoxysilane (3-APTMS) and organic reducing reagents for real time synthesis of amphilic noble metal nanoparticles meeting these requirements are demonstrated justifying the following; (1) 3-APTMS capped noble metal ions are converted into respective metal nanoparticles in the presence of one of organic reducing agents i.e., cyclohexanone, tetrahydrofuran hydroperoxide (THF-HPO), formaldehyde, acetaldehyde, acetone, t-buty dimethyl keotone, 3-Glycidoxy-propyltrimethoxysilane (3-GPTMS); (2) 3-APTMS acts as micelle, promotes the interaction of metal ions with organic reducing agent, precisely controls the size of metal nanoparticles, pH sensititvity and salt tolerance and also provides a suitable medium for nanoparticles suspension, (3) the use of suitable organic reagent precisely controls the polarity of as made noble metal nanoparticles allowing specific biological interactions, and (4) 3-APTMS significantly increases the stability and controls the pH sensitivity and salt tolerance of metal nanoparticles. The as synthesized nanomaterials show potential viability in biomedical applications from many angles i.e. (a) as potential bioelectrocatalyst, (b) selective interaction with active proteins and cellular components, and (c) peroxidase mimetic.

scholarly journals Noble Metal Nanoparticles Applications in Cancer

2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
João Conde ◽  
Gonçalo Doria ◽  
Pedro Baptista
Keyword(s):  
Metal Nanoparticles ◽  
Noble Metal ◽  
Biomedical Applications ◽  
Noble Metal Nanoparticles ◽  
Clinical Settings ◽  
Adverse Side Effects ◽  
Molecular Therapeutics ◽  
Highly Sensitive ◽  
Drug And Gene Delivery

Nanotechnology has prompted new and improved materials for biomedical applications with particular emphasis in therapy and diagnostics. Special interest has been directed at providing enhanced molecular therapeutics for cancer, where conventional approaches do not effectively differentiate between cancerous and normal cells; that is, they lack specificity. This normally causes systemic toxicity and severe and adverse side effects with concomitant loss of quality of life. Because of their small size, nanoparticles can readily interact with biomolecules both at surface and inside cells, yielding better signals and target specificity for diagnostics and therapeutics. This way, a variety of nanoparticles with the possibility of diversified modification with biomolecules have been investigated for biomedical applications including their use in highly sensitive imaging assays, thermal ablation, and radiotherapy enhancement as well as drug and gene delivery and silencing. Here, we review the available noble metal nanoparticles for cancer therapy, with particular focus on those already being translated into clinical settings.

scholarly journals A repertoire of biomedical applications of noble metal nanoparticles

2019 ◽  
Vol 55 (49) ◽  
pp. 6964-6996 ◽  
Author(s):  
Mohammad Azharuddin ◽  
Geyunjian H. Zhu ◽  
Debapratim Das ◽  
Erdogan Ozgur ◽  
Lokman Uzun ◽  
...  
Keyword(s):  
Metal Nanoparticles ◽  
Noble Metal ◽  
Biomedical Applications ◽  
Scientific Community ◽  
Noble Metal Nanoparticles ◽  
Feature Article ◽  
Recent Advances ◽  
Metal Nanomaterials

The emerging properties of noble metal nanoparticles are attracting huge interest from the translational scientific community. In this feature article, we highlight recent advances in the adaptation of noble metal nanomaterials and their biomedical applications in therapeutics, diagnostics and sensing.

An insight into the binding behavior of graphene oxide and noble metal nanoparticles

2021 ◽  
Vol 129 (12) ◽  
pp. 125302
Author(s):  
Wajeeha Saeed ◽  
Zeeshan Abbasi ◽  
Shumaila Majeed ◽  
Sohail Anjum Shahzad ◽  
Abdul Faheem Khan ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Metal Nanoparticles ◽  
Noble Metal ◽  
Noble Metal Nanoparticles ◽  
Binding Behavior ◽  
Insight Into
Sign in / Sign up

Export Citation Format

Share Document