Cortical rotation and messenger RNA localization inXenopusaxis formation

2012 ◽  
Vol 1 (3) ◽  
pp. 371-388 ◽  
Author(s):  
Douglas W. Houston
1989 ◽  
Vol 7 (9) ◽  
pp. 733???740 ◽  
Author(s):  
Michael Taylor ◽  
Terence Cook ◽  
Carl Pearson ◽  
R. Anthony Risdon ◽  
Stanley Peart

Development ◽  
1991 ◽  
Vol 113 (1) ◽  
pp. 55-66 ◽  
Author(s):  
N.J. Pokrywka ◽  
E.C. Stephenson

We have examined cytoskeletal requirements for bicoid (bcd) RNA localization during Drosophila oogenesis. bcd is an anterior morphogen whose proper function relies on the localization of its messenger RNA to the anterior cortex of the egg. Drugs that depolymerize microtubules perturb all aspects of bcd RNA localization. During recovery from drug treatment, bcd RNA relocalizes to the oocyte cortex, suggesting that the localization machinery is a component of the cortical cytoskeleton. Taxol, a drug that stabilizes microtubules, also effectively disrupts bcd RNA localization, and the effects of taxol treatments on exuperantia and swallow mutants suggest general roles for these gene products in the multi-step bcd RNA localization process.


2004 ◽  
Vol 12 (2) ◽  
pp. A24-A24
Author(s):  
Gang Liu ◽  
Lisa A. Mingle ◽  
Nataly N. Okuhama ◽  
Livingston Van De Water ◽  
Robert Harmon

2003 ◽  
Vol 124 (4) ◽  
pp. A279
Author(s):  
Vicki M. Houle ◽  
Wei Li ◽  
Robert K. Montgomery ◽  
Richard J. Grand

2018 ◽  
Author(s):  
Furqan M. Fazal ◽  
Shuo Han ◽  
Pornchai Kaewsapsak ◽  
Kevin R. Parker ◽  
Jin Xu ◽  
...  

SUMMARYWe introduce APEX-seq, a method for RNA sequencing based on spatial proximity to the peroxidase enzyme APEX2. APEX-seq in nine distinct subcellular locales produced a nanometer-resolution spatial map of the human transcriptome, revealing extensive and exquisite patterns of localization for diverse RNA classes and transcript isoforms. We uncover a radial organization of the nuclear transcriptome, which is gated at the inner surface of the nuclear pore for cytoplasmic export of processed transcripts. We identify two distinct pathways of messenger RNA localization to mitochondria, each associated with specific sets of transcripts for building complementary macromolecular machines within the organelle. APEX-seq should be widely applicable to many systems, enabling comprehensive investigations of the spatial transcriptome.


2002 ◽  
Vol 66 (2) ◽  
pp. 524-533 ◽  
Author(s):  
Sophie Fouchécourt ◽  
Pierre Chaurand ◽  
Beverly B. DaGue ◽  
Jean-Jacques Lareyre ◽  
Robert J. Matusik ◽  
...  

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