The determination of polymer additive effects in a spherilene process HDPE matrix upon water carry-over in water quenched, cast film extrusion

1996 ◽  
Vol 2 (2) ◽  
pp. 158-161
Author(s):  
Timothy J. Cowell ◽  
Clayton B. Brunner
Keyword(s):  
Additive Effects ◽  
Polymer Additive ◽  
Film Extrusion ◽  
Cast Film ◽  
Carry Over

scholarly journals Determination of regulatory ionophore coccidiostat residues in feedstuffs at carry-over levels by liquid chromatography-mass spectrometry

PLoS ONE ◽  
2017 ◽  
Vol 12 (8) ◽  
pp. e0182831 ◽  
Author(s):  
Loredana Annunziata ◽  
Pierina Visciano ◽  
Arianna Stramenga ◽  
Maria Novella Colagrande ◽  
Guido Campana ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Liquid Chromatography Mass Spectrometry ◽  
Chromatography Mass Spectrometry ◽  
Carry Over

scholarly journals Development and analytical performance of an automated screening method for cannabinoids on the Dimension clinical chemistry system

1997 ◽  
Vol 19 (5) ◽  
pp. 169-173 ◽  
Author(s):  
D. M. Obzansky ◽  
E. G. Gorman ◽  
S. P. Kramer ◽  
I. S. Masulli ◽  
E. A. Nuzzaci ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Clinical Chemistry ◽  
Screening Method ◽  
Random Access ◽  
Analytical Performance ◽  
Access Method ◽  
Extensive Evaluation ◽  
Automated Screening ◽  
Carry Over

A fully automated, random access method for the determination of cannabinoids (UTHC) was developed for the Dimension AR and XL clinical chemistry systems. The method utilizes Abuscreen ONLINE reagents and a multianalyte liquid calibrator containing 11-nor-Δ9-THC-9-carboxylic acid. Within-run and total reproducibility, determined using NCCLS protocol EP5- T2, was less than 0.6% and 1.6% CV, respectively, at all concentrations. Calibration stability was retained for at least 30 days. An extensive evaluation of non-structurally related drugs and various physiological substances indicated lack of interference in the method. No sample carry-over was observed following a specimen containing 1886 ng/ml 11-nor-Δ9-THC-9-carboxylic acid. A 99.1% agreement (N = 445 samples) was found between an EMIT based method on the aca discrete clinical analyser and the Dimension UTHC method.Dimension clinical chemistry system and aca discrete clinical analyser are registered trademarks of Dade International.

Isothermal and Anisothermal Models for Cast Film Extrusion

1992 ◽  
Vol 7 (4) ◽  
pp. 334-349 ◽  
Author(s):  
P. Barq ◽  
J. M. Haudin ◽  
J. F. Agassant
Keyword(s):  
Film Extrusion ◽  
Cast Film

Cast Film Extrusion of Polypropylene Films

1989 ◽  
Vol 4 (2) ◽  
pp. 103-113 ◽  
Author(s):  
D. Cotto ◽  
P. Duffo ◽  
J. M. Haudin
Keyword(s):  
Film Extrusion ◽  
Cast Film ◽  
Polypropylene Films

DBS Assay with LC-MS/MS for the Determination of Idelalisib, A Selective PI3K-δ Inhibitor in Mice Blood and Its Application to a Pharmacokinetic Study

Drug Research ◽  
2020 ◽  
Vol 71 (01) ◽  
pp. 36-42
Author(s):  
Harsha K. Tripathy ◽  
Nair S.V. Manju ◽  
Sreekanth Dittakavi ◽  
Ashok Zakkula ◽  
Ramesh Mullangi
Keyword(s):  
Pharmacokinetic Study ◽  
Multiple Reaction Monitoring ◽  
Internal Standard ◽  
Lymphocytic Leukemia ◽  
Extraction Solvent ◽  
Non Hodgkin Lymphoma ◽  
Validation Parameters ◽  
Multiple Reaction Monitoring Mode ◽  
Carry Over

AbstractIdelalisib is a selective and second-generation PI3K-δ inhibitor, approved for the treatment of non-Hodgkin lymphoma and chronic lymphocytic leukemia. In this paper, we present a fully validated dried blood spot (DBS) method for the quantitation of idelalisib from mice blood using an LC-MS/MS, which was operated under multiple reaction monitoring mode. To the punched DBS discs, acidified methanol enriched with internal standard (IS; larotrectinib) was added and extracted using tert-butyl methyl ether as an extraction solvent with sonication. Chromatographic separation of idelalisib and the IS was achieved on an Atlantis dC18 column using a mixture of 10 mM ammonium formate:acetonitrile (25:75, v/v). The flow-rate and injection volume were 0.80 mL/min and 2.0 µL, respectively. Idelalisib and the IS were eluted at ~0.98 and 0.93 min, respectively and the total run time was 2.00 min. Idelalisib and the IS were analyzed using positive ion scan mode and parent-daughter mass to charge ion (m/z) transition of 416.1→176.1 and 429.1→342.1, respectively was used for the quantitation. The calibration range was 1.01−4 797 ng/mL. No matrix effect and carry over were observed. Haematocrit did not influence DBS idelalisib concentrations. All the validation parameters met the acceptance criteria. The applicability of the validated method was shown in a mice pharmacokinetic study.

Separation and Determination of Diesel Contaminants in Various Fish Products by Capillary Gas Chromatography

1991 ◽  
Vol 74 (6) ◽  
pp. 986-990
Author(s):  
J M Newton ◽  
Barry S Rothman ◽  
F Ann Walker
Keyword(s):  
Diesel Fuel ◽  
Capillary Column ◽  
Fused Silica ◽  
Fish Products ◽  
Seafood Products ◽  
Fused Silica Capillary ◽  
Carry Over ◽  
Gas Chromatographic Method ◽  
Silica Capillary Column

Abstract A semiquantitative capillary column gas chromatographic method Is described for the determination of diesel fuel contamination in various canned seafood products. The diesel contaminants are separated from the fish sample by steam distillation, with little carry-over of interfering intrinsic materials such as fish oils. The diesel fuel is extracted from the condensate with n-hexane, and the extract is analyzed on an SPB-1 fused silica capillary column. The efficiency of recovery of diesel fuel added to canned seafood at levels of 40-400 ppt ranged from 72 to 102%. With the additional step of concentrating the hexane extract, the sensitivity of this procedure may be increased at least 10-fold. This procedure can detect the differences among diesel fuel grades No. 1,2, and 5, and variations within diesel grade No. 2, and thus may be useful in determining the type of petroleum contaminants present in various canned fish products.

Distributed Crystallinity Control during Cast Film Extrusion

1997 ◽  
Vol 12 (4) ◽  
pp. 373-377 ◽  
Author(s):  
T. Leephakpreeda ◽  
C. Batur
Keyword(s):  
Film Extrusion ◽  
Cast Film
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