scholarly journals Comparison of follicular development, timing of ovulation and serum progesterone, estradiol and luteinizing hormone concentrations in dairy heifers treated with 4‐ or 5‐day CoSynch + CIDR protocols

2019 ◽  
Vol 5 (3) ◽  
pp. 379-389 ◽  
Author(s):  
Heidi Fishman‐Holland ◽  
Agne Stoskute ◽  
Maria S. Ferrer ◽  
Deana Veal ◽  
Joao H. J. Bittar ◽  
...  
Keyword(s):  
Luteinizing Hormone ◽  
Follicular Development ◽  
Serum Progesterone ◽  
Dairy Heifers

EFFECT OF CORTISOL OR ADRENOCORTICOTROPHIN ON RELEASE OF LUTEINIZING HORMONE INDUCED BY LUTEINIZING HORMONE RELEASING HORMONE IN THE DAIRY HEIFER

1982 ◽  
Vol 92 (1) ◽  
pp. 141-146 ◽  
Author(s):  
R. L. MATTERI ◽  
G. P. MOBERG
Keyword(s):  
Luteinizing Hormone ◽  
Luteinizing Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Dairy Heifers ◽  
Significant Difference ◽  
Significant Depression ◽  
Lh Rh ◽  
Lh Releasing Hormone ◽  
And Control ◽  
Slight Depression

During treatment with cortisol or ACTH, dairy heifers were given two doses of LH releasing hormone (LH-RH) spaced 1·5 h apart. Serum concentrations of cortisol and LH were monitored during each treatment. Treatment with both ACTH and cortisol raised plasma cortisol levels above the respective saline controls (P<0·001). Neither treatment affected basal LH concentrations. A slight depression in LH response was seen in the cortisol-treated animals after the first LH-RH injection, as shown by a statistically significant depression at three of the sample times. There was no significant difference between treated and control LH values after the second LH-RH administration. Treatment with ACTH resulted in significantly reduced LH values at all sample times after both injections of LH-RH.

scholarly journals Pentachloronitrobenzene alters progesterone production and primordial follicle recruitment in cultured granulosa cells and rat ovary†

2019 ◽  
Vol 102 (2) ◽  
pp. 511-520
Author(s):  
Yanrong Kuai ◽  
Xiaobo Gao ◽  
Huixia Yang ◽  
Haiyan Luo ◽  
Yang Xu ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Granulosa Cells ◽  
Crop Production ◽  
Follicular Development ◽  
Mitogen Activated Protein Kinase ◽  
Dependent Manner ◽  
Serum Progesterone ◽  
Primordial Follicles ◽  
Progesterone Production

Abstract Pentachloronitrobenzene (PCNB) is an organochlorine fungicide widely used for crop production and has become an environmental concern. Little is known about the effect of PCNB on ovarian steroidogenesis and follicular development. We found that PCNB stimulated Star expression and progesterone production in cultured rat granulosa cells in a dose-dependent manner. PCNB activated mitogen-activated protein kinase (MAPK3/1) extracellulat regulated kinase (ERK1/2), thus inhibition of either protein kinase A (PKA) or MAPK3/1 signaling pathway significantly attenuated progesterone biosynthesis caused by PCNB, suggesting that PCNB induced progesterone production by activating the cyclic adenosine monophosphate (cAMP/PKA) and MAPK3/1 signaling pathways. Further investigation demonstrated that PCNB induced Star expression and altered MAPK3/1 signaling in ovary tissues of immature SD rats treated with PCNB at the dose of 100, 200, or 300 mg/kg by daily gavage for 7 days, while serum progesterone level was dose-dependently decreased. We demonstrated that PCNB exposure accelerated the recruitment of primordial follicles into the growing follicle pool in ovary tissues, accompanied by increased levels of anti-Mullerian hormone (AMH) in both ovary tissues and serum. Taken together, our data demonstrate for the first time that PCNB stimulated Star expression, altered MAPK3/1 signaling and progesterone production in vivo and in vitro, and accelerated follicular development with a concomitant increase in AMH in ovary tissues and serum. Our findings provide novel insight into the toxicity of PCNB to animal ovary function.

PROGESTERONE AND LUTEINIZING HORMONE CONCENTRATION IN SERUM OF PREGNANT GILTS ON DIFFERENT LEVELS OF FEED CONSUMPTION

1980 ◽  
Vol 60 (4) ◽  
pp. 877-884 ◽  
Author(s):  
G. W. DYCK ◽  
W. M. PALMER ◽  
S. SIMARAKS
Keyword(s):  
Luteinizing Hormone ◽  
Feed Consumption ◽  
Blood Collection ◽  
Corpora Lutea ◽  
Serum Progesterone ◽  
Treatment Groups ◽  
Fetal Survival ◽  
Serum Lh ◽  
Luteinizing Hormone Concentration ◽  
Collection Period

Blood serum progesterone (P) and luteinizing hormone (LH) were determined in 31 Lacombe gilts at a 3- to 4-day interval from 10 to 56 days of pregnancy. They were fed 1.50 (L), 2.25 (M) or 3.00 (H) kg of a 16% protein diet/day and had average daily gains of 0.16 ± 0.02 (SE), 0.36 ± 0.02 and 0.60 ± 0.02 kg/day, respectively. All gilts were slaughtered between 59 and 61 days of pregnancy. The treatments had no effect on the number of corpora lutea (13.9 ± 0.4 CL), number of fetuses (10.8 ± 0.6), fetal survival (78.3 ± 3.7%) or mean fetal weight (122 ± 3 g). The gilts on the H level of feeding had heavier (P < 0.05) ovaries (18.4 ± 0.8 g) than those of the L (15.6 ± 0.7 g) or M (15.6 ± 0.8 g) treatment groups. Serum P concentration declined during the blood collection period (b = −0.12, −0.06 and −0.09 for the L, M and H groups, respectively). Serum P concentrations also were different (P < 0.01) for each treatment group (L, 16.7 ± 0.3; M, 13.8 ± 0.03; and H, 11.8 ± 0.3 ng/mL). The serum LH concentration was greater (P < 0.05) for the M gilts (0.63 ± 0.05 ng/mL) than for the L (0.37 ± 0.04 ng/mL) or H (0.47 ± 0.05 ng/mL) gilts. Significant correlations were observed among the number of fetuses, number of CL, ovarian weight and P for the L gilts, and the number of fetuses and CL for the M gilts. These results suggest that growth rate is a major contributor to differences in blood P and LH concentrations during pregnancy and that the animal adjusts its P and LH production to its specific requirements for the maintenance of pregnancy.

PROGESTERONE-INDUCED AUGMENTATION OF PITUITARY GONADOTROPHIN RESPONSES TO LUTEINIZING HORMONE-RELEASING HORMONE IN OESTROGEN-PRE-TREATED AMENORRHOEIC WOMEN

1976 ◽  
Vol 83 (4) ◽  
pp. 684-691 ◽  
Author(s):  
Sven Johan Nillius ◽  
Leif Wide
Keyword(s):  
Luteinizing Hormone ◽  
Follicle Stimulating Hormone ◽  
Follicular Phase ◽  
Reserve Capacity ◽  
Serum Progesterone ◽  
Luteinizing Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Before And After ◽  
The Mean ◽  
Late Follicular Phase

ABSTRACT Modulating effects of oestradiol-17β and progesterone on the pituitary responsiveness to luteinizing hormone-releasing hormone (LRH) were investigated in 12 women with functional amenorrhoea. The pituitary reserve capacity for gonadotrophin section was investigated with repeated intravenous LRH tests before and after administration of oestradiol-1β followed by either progesterone or saline. Intramuscular injection of 1 mg of oestradiol-17β benzoate resulted in a suppression of both the basal gonadotrophin levels in serum and the gonadotrophin responses to LRH 24 h later. Progesterone, 25 mg im, was then administered in eleven experiments. Six h later, when the mean serum progesterone level had increased to levels similar to those seen in the early post-ovulatory phase of the menstrual cycle, there was a marked augmentation of the pituitary capacity to release both luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in response to LRH. This was not found in eight experiments where saline was given instead of progesterone after oestrogen pretreatment. These findings suggest that the greatly increased pituitary sensitivity to LRH at midcycle may be caused not only by the oestradiol increase in blood during the late follicular phase but also in part by the small pre-ovulatory rise of progesterone during the mid-cyclic LH peak. Furthermore, they add further support to the hypothesis that progesterone as well as oestradiol is involved in the induction of the LH peak at midcycle. Progesterone may be of importance to secure the release of enough LH for ovulation and normal corpus luteum formation to occur.

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