scholarly journals OP36.07: A novel method of true global fetal perfusion measurement from three-dimensional color Doppler data with the PixelFlux-technique

2011 ◽  
Vol 38 (S1) ◽  
pp. 160-160
Author(s):  
T. M. Scholbach ◽  
J. Stolle ◽  
J. Scholbach ◽  
N. Fersis
Keyword(s):  
Color Doppler ◽  
Three Dimensional ◽  
Perfusion Measurement ◽  
Doppler Data ◽  
Novel Method

Three-Dimensional Volumetric Spatially Angle-Corrected Pixelwise Fetal Flow Volume Measurement

2011 ◽  
Vol 32 (S 02) ◽  
pp. E122-E128 ◽  
Author(s):  
T. Scholbach ◽  
J. Stolle ◽  
J. Scholbach
Keyword(s):  
Umbilical Vein ◽  
Color Doppler ◽  
Three Dimensional ◽  
Volume Measurement ◽  
Data Sets ◽  
Volume Data ◽  
Flow Measurements ◽  
Perfusion Measurement ◽  
Actual Flow ◽  
Relationship Of

Abstract Purpose: Early attempts to calculate fetal global perfusion used 2 D images. The results were not sufficiently reliable. That‘s why RI measurements are still in use despite the fact that they do not reflect the amount of blood passing through the fetus. We present a novel three-dimensional approach to overcome these limitations. Materials and Methods: In 124 singleton pregnancies between the 23rd and 4st gestational week, a three-dimensional color Doppler sonographic record of the umbilical cord was made, resulting in 281 volume data sets. With dedicated software (PixelFlux) the spatial angle of the umbilical vein was calculated and the true global fetal perfusion was calculated from its horizontal transection as the product of the area of all pixels and the spatial angle-corrected velocity. To validate the PixelFlux technique, phantom flow measurements were carried out. Results: Phantom flow measurements revealed a highly significant correlation of actual flow volumes and those measured by the PixelFlux technique (p < 0.001; rPearson = 0.987 – 0.991) with an even higher interobserver correlation (p < 0.001; rPearson = 0.997). We found a significant correlation of fetal volume flow to gestational age and weight (r = 0.529 at spatial angles below 30° to r = 0.724 at spatial angles below 5°) and a significant influence of the spatial angle on this correlation (p = 0.003; r = – 0.865). Conclusion: Spatial angle-corrected global fetal perfusion measurement improves existing approaches to fetal perfusion evaluation, and is feasible, simple and fast. Thus, it can be recommended to explore the relationship of fetal perfusion and disturbances of fetal development.

Automated Cardiac Output Measurement by Spatiotemporal Integration of Color Doppler Data

Circulation ◽  
1997 ◽  
Vol 95 (4) ◽  
pp. 932-939 ◽  
Author(s):  
Jing Ping Sun ◽  
Min Pu ◽  
Fetnat M. Fouad ◽  
Raymond Christian ◽  
William J. Stewart ◽  
...  
Keyword(s):  
Cardiac Output ◽  
Color Doppler ◽  
Cardiac Output Measurement ◽  
Output Measurement ◽  
Doppler Data ◽  
Spatiotemporal Integration

scholarly journals Homogeneous 2D and 3D alignment of cardiomyocyte in dilated cardiomyopathy revealed by intravital heart imaging

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kiyoshi Masuyama ◽  
Tomoaki Higo ◽  
Jong-Kook Lee ◽  
Ryohei Matsuura ◽  
Ian Jones ◽  
...  
Keyword(s):  
Heart Failure ◽  
Dilated Cardiomyopathy ◽  
Cardiac Dysfunction ◽  
Three Dimensional ◽  
Single Layer ◽  
Specific Pattern ◽  
Two Dimensional ◽  
Heart Imaging ◽  
Novel Method ◽  
2D And 3D

AbstractIn contrast to hypertrophic cardiomyopathy, there has been reported no specific pattern of cardiomyocyte array in dilated cardiomyopathy (DCM), partially because lack of alignment assessment in a three-dimensional (3D) manner. Here we have established a novel method to evaluate cardiomyocyte alignment in 3D using intravital heart imaging and demonstrated homogeneous alignment in DCM mice. Whilst cardiomyocytes of control mice changed their alignment by every layer in 3D and position twistedly even in a single layer, termed myocyte twist, cardiomyocytes of DCM mice aligned homogeneously both in two-dimensional (2D) and in 3D and lost myocyte twist. Manipulation of cultured cardiomyocyte toward homogeneously aligned increased their contractility, suggesting that homogeneous alignment in DCM mice is due to a sort of alignment remodelling as a way to compensate cardiac dysfunction. Our findings provide the first intravital evidence of cardiomyocyte alignment and will bring new insights into understanding the mechanism of heart failure.

scholarly journals The Use of Right Angle Fluorescence Spectroscopy to Distinguish the Botanical Origin of Greek Common Honey Varieties

2021 ◽  
Vol 11 (9) ◽  
pp. 4047
Author(s):  
Marinos Xagoraris ◽  
Panagiota-Kyriaki Revelou ◽  
Eleftherios Alissandrakis ◽  
Petros A. Tarantilis ◽  
Christos S. Pappas
Keyword(s):  
Fluorescence Spectroscopy ◽  
External Validation ◽  
Three Dimensional ◽  
Excitation Wavelength ◽  
Botanical Origin ◽  
Linear Discriminant ◽  
Classification Score ◽  
Hydroxybenzoic Acids ◽  
Unifloral Honey ◽  
Novel Method

The standardization of the botanical origin of honey reflects the commercial value and quality of honey. Nowadays, most consumers are looking for a unifloral honey. The aim of the present study was to develop a novel method for honey classification using chemometric models based on phenolic compounds analyzed with right angle fluorescence spectroscopy, coupled with stepwise linear discriminant analysis (LDA). The deconstructed spectrum from three-dimensional-emission excitation matrix (3D-EEM) spectra provided a correct classification score of 94.9% calibration and cross-validation at an excitation wavelength (λex) of 330 nm. Subsequently, a score of 81.4% and 79.7%, respectively, at an excitation wavelength (λex) of 360 nm was achieved. Each chemometric model confirmed its power through the external validation with a score of 82.1% for both. Differentiation could be correlated with hydroxycinnamic and hydroxybenzoic acids, which absorb in this region of the spectrum. Fluorescence spectroscopy constitutes a rapid and sensitive technique, which, when combined with the stepwise algorithm and LDA method, can be used as a reliable and predictive authentication tool for honey. This study indicates that the developed methodology is a promising technique for determination of the botanical origin of common Greek honey varieties. Our long-term ambition is to support producers and suppliers to remain in a competitive national and international market.

scholarly journals Three-Dimensional Arterial Pulse Signal Acquisition in Time Domain Using Flexible Pressure-Sensor Dense Arrays

Micromachines ◽  
2021 ◽  
Vol 12 (5) ◽  
pp. 569
Author(s):  
Jianzhong Chen ◽  
Ke Sun ◽  
Rong Zheng ◽  
Yi Sun ◽  
Heng Yang ◽  
...  
Keyword(s):  
Radial Artery ◽  
Pressure Sensor ◽  
Pulse Width ◽  
Printed Circuit Boards ◽  
Color Doppler ◽  
Three Dimensional ◽  
Pressure Sensors ◽  
Sensor Arrays ◽  
Signal Acquisition ◽  
Dynamic Pulse

In this study, we developed a radial artery pulse acquisition system based on finger-worn dense pressure sensor arrays to enable three-dimensional pulse signals acquisition. The finger-worn dense pressure-sensor arrays were fabricated by packaging 18 ultra-small MEMS pressure sensors (0.4 mm × 0.4 mm × 0.2 mm each) with a pitch of 0.65 mm on flexible printed circuit boards. Pulse signals are measured and recorded simultaneously when traditional Chinese medicine practitioners wear the arrays on the fingers while palpating the radial pulse. Given that the pitches are much smaller than the diameter of the human radial artery, three-dimensional pulse envelope images can be measured with the system, as can the width and the dynamic width of the pulse signals. Furthermore, the array has an effective span of 11.6 mm—3–5 times the diameter of the radial artery—which enables easy and accurate positioning of the sensor array on the radial artery. This study also outlines proposed methods for measuring the pulse width and dynamic pulse width. The dynamic pulse widths of three volunteers were measured, and the dynamic pulse width measurements were consistent with those obtained by color Doppler ultrasound. The pulse wave velocity can also be measured with the system by measuring the pulse transit time between the pulse signals at the brachial and radial arteries using the finger-worn sensor arrays.

Three-dimensional Color Doppler Sonography and Uterine Artery Arteriography of Fibroids

2002 ◽  
Vol 21 (2) ◽  
pp. 129-133 ◽  
Author(s):  
C. Joseph Muniz ◽  
Arthur C. Fleischer ◽  
Edwin F. Donnelly ◽  
Murray J. Mazer
Keyword(s):  
Uterine Artery ◽  
Doppler Sonography ◽  
Color Doppler ◽  
Three Dimensional ◽  
Color Doppler Sonography
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