scholarly journals Assessment of right ventricular global and regional longitudinal peak systolic strain, strain rate and velocity in healthy fetuses and impact of gestational age using a novel speckle/feature-tracking based algorithm

2010 ◽  
Vol 37 (2) ◽  
pp. 143-149 ◽  
Author(s):  
A. M. Willruth ◽  
A. K. Geipel ◽  
R. Fimmers ◽  
U. G. Gembruch
Keyword(s):  
Right Ventricular ◽  
Strain Rate ◽  
Gestational Age ◽  
Feature Tracking ◽  
Systolic Strain ◽  
Peak Systolic Strain

P674Behavior of 2D and 3D derived ejection fraction and strain in patients with Hodgkin and non-Hodgkin lymphoma undergoing anthracycline-based chemotherapy, a prospective study

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
L F Nhola ◽  
T Daramola ◽  
S Barros-Gomes ◽  
J S Rico-Mesa ◽  
M C Arciniegas ◽  
...  
Keyword(s):  
Ejection Fraction ◽  
Right Ventricular ◽  
Strain Rate ◽  
Circumferential Strain ◽  
Area Under The Curve ◽  
Left Ventricular Ejection ◽  
Systolic Strain ◽  
Peak Systolic Strain ◽  
Diastolic Strain Rate ◽  
2D And 3D

Abstract Background Anthracyclines are one of the most effective chemotherapeutic agents but can lead to a decline in cardiac function. Two-dimensional (2D) speckle tracking echocardiography derived strain can predict cancer therapeutics-related cardiac dysfunction (CTRCD). However, little is known about the role of three-dimensional (3D) strain imaging in this setting. Purpose To evaluate different methods of Left Ventricular Ejection Fraction (LVEF) and strain, and to identify the best strain parameter for the prediction of CTRCD in this group of patients during treatment with anthracycline based chemotherapy. Methods Patients with Hodgkin's or non-Hodgkin's lymphoma receiving anthracycline based chemotherapy were enrolled. 2D-and 3D echocardiography was performed at 3 time points: baseline, at the completion of chemotherapy and at 1 year. 2D- and 3D LVEF (2D Modified Quinones, M-mode, 2D Biplane, 3D Philips, 3D GE and 3D TomTec), peak systolic left and right ventricular longitudinal, radial and circumferential strain and strain rate were measured. CTRCD was defined as a decrease in LVEF >10% to an absolute value of <53%. Lin's Concordance Correlation Coefficient (CCC) was calculated to compare LVEF methods. ANOVA, uni and multivariate analysis was performed. Results A total of 130 patients (79 males, mean age 57±16 years) were enrolled; 104 non-Hodgkin.3D Philips and GE (CCC 0.88 [0.84, 0.92]), 3D Philips and biplane (CCC 0.84 [0.79, 0.89]), 3D Philips and Modified Quinones (CCC 0.86 [0.82, 091]) as well as 3D Philips and M-mode (CCC 0.77 [0.70, 0.85]) showed strong correlation for LVEF. 15 patients (12%) developed CTRCD. Mean cumulative anthracycline dose was 263±65 mg/m2. 2D and 3D global longitudinal and circumferential peak systolic strain, 2D global longitudinal systolic and early diastolic strain rate, 2D global early diastolic strain rate, 2D right ventricular longitudinal peak systolic strain and systolic strain rate, 2D global radial peak systolic strain and systolic strain rate measured at the completion of chemotherapy were independent predictors of the development of CTRCD at 1 year post-chemotherapy. The strongest predictors of CTRCD were 3D global longitudinal and circumferential strain either individually (area under the curve, 0.90 and 0.95 respectively) or combined (area under the curve, 0.95) at the completion of chemotherapy; a cutoff value of <-18% in 3D global longitudinal strain had a sensitivity of 82% and specificity of 99%, while for 3D global circumferential peak systolic strain of <-24% had a sensitivity of 82% and specificity of 95%. Conclusions To our knowledge this is the first prospective trial that shows that 3D EF correlates well with other EF methods and 3D strain predicts cardiac toxicity in this group of patients with a very good sensitivity and specificity. Acknowledgement/Funding Department of Cardiovascular Medicine-Mayo Clinic Rochester MN

scholarly journals Lipopolysaccharide acutely suppresses right-ventricular strain in rats with pulmonary artery hypertension

2017 ◽  
Vol 8 (1) ◽  
pp. 204589321774450 ◽  
Author(s):  
Junjie Zhang ◽  
Yanan Cao ◽  
Xiaowei Gao ◽  
Maoen Zhu ◽  
Zhong Zhang ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Right Ventricular ◽  
Strain Rate ◽  
Acute Inflammation ◽  
Pulmonary Artery Hypertension ◽  
Left Ventricular ◽  
Systolic Strain ◽  
Peak Systolic Strain ◽  
Strain And Strain Rate ◽  
Rv Function

Worsening right ventricular (RV) dysfunction in the presence of pulmonary artery hypertension (PAH) increases morbidity and mortality in this patient population. Transthoracic echocardiography (TTE) is a non-invasive modality to evaluate RV function over time. Using a monocrotaline-induced PAH rat model, we evaluated the effect of acute inflammation on RV function. In this study, both PAH and control rats were injected with Escherichia coli lipopolysaccharide (LPS) to induce an acute inflammatory state. We evaluated survival curves, TTE parameters, and inflammatory markers to better understand the mechanism and impact of acute inflammation on RV function in the presence of PAH. The survival curve of the PAH rats dropped sharply within 9 h after LPS treatment. Several echocardiographic parameters including left ventricular (LV) stroke volume, RV tricuspid annular plane systolic excursion, RV longitudinal peak systolic strain, and strain rate decreased significantly in PAH rats before LPS injection and 2 h after LPS injection. The expression of phospholamban (PLB) and tumor necrosis factor-α (TNF-α) significantly increased and the expression of SERCA2a significantly decreased in PAH rats after LPS administration. LPS suppressed the RV longitudinal peak systolic strain and strain rate and cardiac function deteriorated in PAH rats. These effects may be associated with the signal pathway activity of SERCA2a/PLB.

Regional right and left ventricular function after the Senning operation: an ultrasonic study of strain rate and strain

2004 ◽  
Vol 14 (3) ◽  
pp. 255-264 ◽  
Author(s):  
Benedicte Eyskens ◽  
Frank Weidemann ◽  
Miroslaw Kowalski ◽  
Jan Bogaert ◽  
Steven Dymarkowski ◽  
...  
Keyword(s):  
Ejection Fraction ◽  
Right Ventricle ◽  
Right Ventricular ◽  
Strain Rate ◽  
Ventricular Function ◽  
Right Ventricular Ejection Fraction ◽  
Systolic Strain ◽  
Ventricular Ejection Fraction ◽  
Peak Systolic Strain ◽  
The Right

Background:Systemic right ventricular dysfunction is a major concern in the follow-up of patients who underwent an atrial redirection procedure for transposition (concordant atrio-ventricular and discordant ventriculo-arterial connections). No good non-invasive method is currently available for quantifying right ventricular function.Aims:We have used ultrasonically based imaging of strain rate and strain to quantify regional deformation in the right ventricle after the Senning operation, comparing properties of regional deformation of the right ventricle with right ventricular ejection fraction as measured using magnetic resonance imaging.Methods:In 20 asymptomatic patients who had undergone the Senning procedure, we measured peak systolic strain rate and systolic strain values in the right ventricular free wall, the septum and the left ventricular lateral wall using colour Doppler myocardial imaging, comparing the data with findings obtained in 30 healthy subjects. Global right ventricular ejection fraction was assessed using magnetic resonance imaging.Results:Properties of deformation of the right ventricular free wall were reduced and homogeneous after the Senning procedure compared to normals, with significantly lower values for peak systolic strain rate and systolic strain (−1.1 ± 0.4 vs. −2.5 ± 0.9 s−1; p < 0.05 and −16 ± 7% vs. −38 ± 13%; p < 0.05, respectively). There was a significant correlation between regional longitudinal right ventricular systolic strain values and right ventricular ejection fraction (r = −0.87, p < 0.001). In the septum, peak systolic strain rate was again reduced and homogeneous (−1.2 ± 0.4 vs. −1.8 ± 0.5 s−1; p < 0.05 vs. normals). Also in the left ventricle, the lateral wall peak systolic strain rate and systolic strain values were reduced (−1.5 ± 0.5 vs. −2.1 ± 0.9 s−1; p < 0.05 and −20 ± 6% vs.−25 ± 9%; p < 0.05, vs. normals, respectively).Conclusions:Properties of regional longitudinal deformation of the systemic right ventricle are reduced after the Senning procedure compared to normal controls, and correlate well with global right ventricular performance. These findings suggest that ultrasonic strain rate and strain imaging could be used in the non-invasive follow-up of ventricular function in these patients.

scholarly journals The Association of Echocardiographic Peak Systolic Strain Rate with Cardiovascular Outcomes in Haemodialysis Patients

2018 ◽  
Vol 43 (6) ◽  
pp. 1935-1942 ◽  
Author(s):  
John Hughes ◽  
Darren Green ◽  
Diana Y.Y. Chiu ◽  
Nik Abidin ◽  
Philip A. Kalra
Keyword(s):  
Strain Rate ◽  
Cardiovascular Outcomes ◽  
Systolic Strain ◽  
Peak Systolic Strain

Transmural Peak Systolic Strain and Strain Rate Predict Transmural Myocardial Blood Flow in a Pig Myocardial Infarction Model

Cardiology ◽  
2009 ◽  
Vol 112 (2) ◽  
pp. 122-128 ◽  
Author(s):  
Huixia Lu ◽  
Guihua Yao ◽  
Huili Lin ◽  
Xinsheng Xu ◽  
Changjiang Li ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Blood Flow ◽  
Myocardial Blood Flow ◽  
Strain Rate ◽  
Systolic Strain ◽  
Peak Systolic Strain ◽  
Strain And Strain Rate

scholarly journals Prognostic Value of Right Ventricular Longitudinal Peak Systolic Strain in Patients With Pulmonary Hypertension

2012 ◽  
Vol 5 (5) ◽  
pp. 628-636 ◽  
Author(s):  
Marlieke L.A. Haeck ◽  
Roderick W.C. Scherptong ◽  
Nina Ajmone Marsan ◽  
Eduard R. Holman ◽  
Martin J. Schalij ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Right Ventricular ◽  
Prognostic Value ◽  
Systolic Strain ◽  
Peak Systolic Strain

Feature Tracking-Derived Peak Systolic Strain Compared to Late Gadolinium Enhancement in Troponin-Positive Myocarditis: A Case–Control Study

2015 ◽  
Vol 37 (4) ◽  
pp. 696-703 ◽  
Author(s):  
Justin Weigand ◽  
James C. Nielsen ◽  
Partho P. Sengupta ◽  
Javier Sanz ◽  
Shubhika Srivastava ◽  
...  
Keyword(s):  
Late Gadolinium Enhancement ◽  
Feature Tracking ◽  
Case Control Study ◽  
Case Control ◽  
Systolic Strain ◽  
Gadolinium Enhancement ◽  
Peak Systolic Strain ◽  
Control Study
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