Abnormal first-trimester ductus venosus blood flow: a marker of cardiac defects in fetuses with normal karyotype and nuchal translucency

2010 ◽  
Vol 35 (3) ◽  
pp. 267-272 ◽  
Author(s):  
J. M. Martínez ◽  
M. Comas ◽  
A. Borrell ◽  
M. Bennasar ◽  
O. Gómez ◽  
...  
2003 ◽  
Vol 188 (3) ◽  
pp. 727-733 ◽  
Author(s):  
Monique C. Haak ◽  
Jos W.W.R. Twisk ◽  
Margot M. Bartelings ◽  
Adriana C. Gittenberger-de Groot ◽  
John M.G. van Vugt

Author(s):  
Nuno Montenegro ◽  
Alexandra Matias

ABSTRACT Ductus venosus (DV) is a tiny vessel with a central role in fetal circulation both in singletons and multiples. In the present review we detail the contribution of DV evaluation in twin pregnancies in the first trimeter of pregnancy. The higher prevalence of abnormal A-wave in fetuses with abnormal karyotype and/or cardiac defects made DV evaluation a useful marker for the screening of chromosomal abnormalities and fetal cardiac anomalies. In dichorionic (DC) pregnancies, DV blood flow assessment reproduces the role of NT in the screening for aneuploidies, just as in singleton pregnancies. In monochorionic (MC) twin pregnancies, the Doppler assessment of DV blood flow improves the detection of those at higher risk of developing twin-to-twin transfusion syndrome or growth discrepancy later in pregnancy. As for singletons, DV should be systematically evaluated in all first trimester scans for a more performant screening in multiples. How to cite this article Matias A, Montenegro N. Improving our Knowledge in Twins: The Role of Ductus Venosus in the First Trimester. Donald School J Ultrasound Obstet Gynecol 2013;7(4):409-414.


2014 ◽  
Vol 44 (S1) ◽  
pp. 62-62
Author(s):  
N. Karadzov-Orlic ◽  
A. Egic ◽  
B. Damnjanovic-Pazin ◽  
Z. Milovanovic ◽  
R. Lukic ◽  
...  

Author(s):  
Nuno Montenegro ◽  
Alexandra Matias

ABSTRACT Ductus venosus is a tiny vessel with a central role in fetal circulation. Combining B-mode with color and pulsed Doppler is feasible to identify this vessel and evaluate the blood flow waveform at 11 to 13 weeks. The higher prevalence of abnormal A-wave in fetuses with abnormal karyotype and/or cardiac defects turned DV evaluation into a useful marker for chromosomal abnormalities and cardiopathies. Even when combined with nuchal translucency (NT) or biochemical markers, DV blood flow evaluation contributes to an increase in sensitivity and reduces false-positive rate. Abnormal ductal flow is also related to a worse fetal and perinatal outcome. In monochorionic twin pregnancies, in addition to NT measurement at 11 to 14 weeks, the Doppler assessment of DV blood flow increases relevantly the performance of screening for those at higher risk of developing twin-to-twin transfusion syndrome. This story of 14 years surely contributed to change the way first trimester screening is being implemented.


2013 ◽  
Vol 42 (1) ◽  
pp. 51-57 ◽  
Author(s):  
A. Borrell ◽  
M. Grande ◽  
M. Bennasar ◽  
V. Borobio ◽  
J. M. Jimenez ◽  
...  

Author(s):  
O.L. Galkina

Objectives: to analyze the characteristics of blood flow in the ductus venosus of fetus with congenital anomalies diagnosed during the first trimester. Materials: 20 821 first trimester pregnant women have been examined during the last 3 years. 82 fetuses have been diagnosed with congenital anomalies. In 74 out of 82 cases assessment of blood flow took place. A comparative analysis of the following parameters has been carried out: characteristics of blood flow in the ductus venosus of fetus with multiple and isolated congenital anomalies, normal nuchal translucency and expanded nuchal translucency, isolated and concomitant development anomalies of the heart and major vessels, normal and anomalous karyotype. Results: anomalous blood flow in the ductus venosus was recorded in 40 % of the fetuses with congenital anomalies – the highest in the group of fetus with multiple congenital anomalies in combination with the expanded nuchal translucency and chromosomal abnormalities – 60 %, in the group of fetus with Edwards syndrome – 90 %. Conclusion: the recording of abnormal blood flow in the ductus venosus of a fetus should be an indication for an expanded anatomical assessment of the fetus and ultrasound monitoring, as sensitive markers of fetal anomalies and chromosomal abnormalities.


2015 ◽  
Vol 35 (13) ◽  
pp. 1308-1315 ◽  
Author(s):  
Natasa Karadzov-Orlic ◽  
Amira Egic ◽  
Dejan Filimonovic ◽  
Barbara Damnjanovic-Pazin ◽  
Zagorka Milovanovic ◽  
...  

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