scholarly journals OP32.05: Estimated fetal weight Z-score and amniotic fluid index as predictors of neonatal respiratory distress syndrome in indicated Cesarean preterm delivery

2009 ◽  
Vol 34 (S1) ◽  
pp. 166-166
Author(s):  
K. Lee ◽  
C. Park ◽  
J. Park ◽  
J. Jun ◽  
B. Yoon ◽  
...  
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Amniotic Fluid ◽  
Preterm Delivery ◽  
Distress Syndrome ◽  
Fetal Weight ◽  
Z Score ◽  
Amniotic Fluid Index ◽  
Neonatal Respiratory Distress ◽  
Estimated Fetal Weight

scholarly journals A New Approach to Prevent Neonatal Respiratory Distress Syndrome: A randomized clinical trial of 25(OH) D Injections before Preterm Delivery

2021 ◽  
Author(s):  
Hassan Boskabadi ◽  
Gholamali Maamouri ◽  
Nafiseh Saghafi ◽  
Mohammad Hosein Ataee Nakhaei
Keyword(s):  
Clinical Trial ◽  
At Risk ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Pregnant Women ◽  
Preterm Delivery ◽  
Gestational Age ◽  
Distress Syndrome ◽  
Neonatal Respiratory Distress ◽  
And Control

Abstract BackgroundVitamin D deficiencies have been suggested as one of the risk factors for neonatal respiratory distress syndrome (RDS). The present study aimed to evaluate the effect of 25-hydroxyvitamin D [25(OH)D] administration in pregnant women at risk of preterm delivery on the incidence of RDS in their preterm neonates.MethodsA single-blinded randomized controlled clinical trial was conducted on pregnant mothers with a gestational age of less than 34 weeks at risk of preterm delivery. Subjects were randomly assigned into two groups by the corresponding author, including intervention (intramuscular injection of 50,000 units of 25(OH) D three days before delivery) and control (with no injection of 25(OH) D). Serum concentrations of 25(OH) D were measured after offspring, including RDS, were collected and recorded in a checklist. Short-term outcomes and the need for respiratory support were assessed by the principal investigator who was unaware of the type of intervention. Data were analyzed by independent t-test, paired sample t-test, and chi-square test.ResultsDespite the homogeneity of neonates in the two groups in terms of gestational age, birth weight and the delivery method, 45% of neonates in the control group and 20% in the intervention group developed respiratory distress syndrome (P < 0.05). The mean 25(OH) D level in neonates was 17.7 ± 10.5 and 23.7 ± 13.5 ng/mL in the intervention and control groups, respectively.ConclusionsAccording to this study, a single dose of 50,000 units of intramuscular 25(OH) D in pregnant women at risk of preterm delivery can reduce the incidence of RDS in the newborn.Trial RegistrationIranian Registry of Clinical Trials, IRCT20190814044529N1. Registered 21st Jan. 2020, https://fa.irct.ir/user/trial/41515/view

Aerosolized surfactant in neonatal respiratory distress syndrome: Phase I study

2019 ◽  
Vol 134 ◽  
pp. 19-25 ◽  
Author(s):  
Beena G. Sood ◽  
Josef Cortez ◽  
Madhuri Kolli ◽  
Amit Sharma ◽  
Virginia Delaney-Black ◽  
...  
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Phase I ◽  
Phase I Study ◽  
Distress Syndrome ◽  
Neonatal Respiratory Distress Syndrome ◽  
Neonatal Respiratory Distress
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