scholarly journals P230: Doppler flow in the fetal circulation?III. Ductus venosus in predicting fetal acidemia

2003 ◽  
Vol 22 (S1) ◽  
pp. 132-132
Author(s):  
L. Lopes ◽  
R. A. M. S� ◽  
T. Almeida ◽  
Y. Cosmo ◽  
I. B. Costa ◽  
...  
2003 ◽  
Vol 22 (S1) ◽  
pp. 132-132
Author(s):  
L. Lopes ◽  
R. A. M. S� ◽  
P. R. Marinho ◽  
P. C. Gomes ◽  
P. R. N. Carvalho ◽  
...  

2003 ◽  
Vol 22 (S1) ◽  
pp. 132-132
Author(s):  
R. A. M. S� ◽  
L. M. Lopes ◽  
A. L. Dourado ◽  
B. C. Novaes ◽  
C. P. Werner ◽  
...  

2020 ◽  
Vol 23 (5) ◽  
pp. 292-297
Author(s):  
Mayumi Takano ◽  
Masahiko Nakata ◽  
Sumito Nagasaki ◽  
Junya Sakuma ◽  
Mineto Morita

AbstractWe aimed to investigate whether the alterations of time intervals and velocity–time integrals (VTIs) of ductus venosus (DV) Doppler flow could predict evolving twin-to-twin transfusion syndrome (TTTS) in monochorionic diamniotic (MD) twin pregnancies in the second trimester. DV Doppler waveforms of MD twin pregnancies were retrospectively analyzed. Time intervals and VTIs of the accelerating phase of S-wave (S1 and VTI-1), decelerating phase of S-wave (S2 and VTI-2) and phase of D-wave (D and VTI-diast) were measured in the recipient twins of TTTS and the larger twins of uncomplicated MD twins. Each parameter was normalized to total time intervals and VTIs. DV parameters of prerecipient twins in pre-TTTS conditions were analyzed. The pre-TTTS condition was defined as the condition within 2 weeks before when TTTS cases fulfilled the criteria. Both recipient twins in TTTS cases and prerecipient twins in pre-TTTS condition showed significantly shorter S1, longer S2, shorter D, smaller VTI-1, larger VTI-2 and smaller VTI-diast than did the larger twins in uncomplicated MD twins (p < .05). Receiver-operating characteristic curve analysis showed that VTI-2 had better performance, and VTI-2 >45.5% had 87.0% sensitivity, 90.9% specificity, 81.0% positive predictive value and 93.0% negative predictive value for detecting prerecipient twins. Recipient twins complicated with TTTS have characteristic alterations in time intervals and VTIs of DV Doppler flow, which is present even before fulfilling the TTTS criteria. Furthermore, VTI-2 >45.5% is a possible predictive parameter for TTTS in the second trimester.


2019 ◽  
Vol 317 (6) ◽  
pp. R780-R792 ◽  
Author(s):  
An Qi Duan ◽  
Jack R. T. Darby ◽  
Jia Yin Soo ◽  
Mitchell C. Lock ◽  
Meng Yuan Zhu ◽  
...  

Phase-contrast cine MRI (PC-MRI) is the gold-standard noninvasive technique for measuring vessel blood flow and has previously been applied in the human fetal circulation. We aimed to assess the feasibility of using PC-MRI to define the distribution of the fetal circulation in sheep. Fetuses were catheterized at 119–120 days of gestation (term, 150 days) and underwent MRI at ∼123 days of gestation under isoflurane anesthesia, ventilated at a [Formula: see text] of 1.0. PC-MRI was performed using a fetal arterial blood pressure catheter signal for cardiac triggering. Blood flows were measured in the major fetal vessels, including the main pulmonary artery, ascending and descending aorta, superior vena cava, ductus arteriosus, left and right pulmonary arteries, umbilical vein, ductus venosus, and common carotid artery and were indexed to estimated fetal weight. The combined ventricular output, pulmonary blood flow, and flow across the foramen ovale were calculated from vessel flows. Intraobserver and interobserver agreement and reproducibility was assessed. Blood flow measurements were successfully obtained in 61 out of 74 vessels (82.4%) interrogated in 9 fetuses. There was good intraobserver [ R = 0.998, P < 0.0001; intraclass correlation (ICC) = 0.997] and interobserver agreement ( R = 0.996, P < 0.0001; ICC = 0.996). Repeated MRI measurements showed good reproducibility ( R = 0.989, P = 0.0002; ICC = 0.990). We conclude that PC-MRI using fetal catheters for gating triggers is feasible in the major vessels of late gestation fetal sheep. This approach may provide a useful new tool for assessing the circulatory characteristics of fetal sheep models of human disease, including fetal growth restriction and congenital heart disease.


1993 ◽  
Vol 5 (1) ◽  
pp. 45-55 ◽  
Author(s):  
Tjeerd WA Huisman ◽  
Juriy W Wladimiroff

The ductus venosus is a blood vessel functioning exclusively in the fetal circulation. According to many reports it was described for the first time by Giulio Cesare Arantius (Bologna 1530–1589) in his bookDe humano foetu libellus(1563) and it is often referred to as the ductus Arantii. Thorough research, however, has made it clear that Andreas Vesalius described this vessel in 1561 in his bookExamen observationium Falloppii, which was published three years later. Moreover, it has been pointed out that the first and second editions of Arantius’s book did not contain a description of the ductus venosus but that this appeared in the 1571 edition.


1969 ◽  
Vol 30 (5) ◽  
Author(s):  
Burcu Artunc Ulkumen ◽  
Halil Gursoy Pala ◽  
Yesim Bulbul Baytur ◽  
Faik Mumtaz Koyuncu

2015 ◽  
Vol 8 (7) ◽  
pp. 172 ◽  
Author(s):  
Homeira Vafaei ◽  
Tarlan Zamanpour ◽  
Hadi Raeisi Shahraki

<p><strong>OBJECTIVE: </strong>The present study aimed to evaluate the effect of vaginal progesterone administration on maternal and fetal circulation to prevent preterm birth.</p><p><strong>METHODS:</strong> The present prospective study was conducted on 35 women with singleton pregnancy at 18–33 weeks of gestation, who presented with at least one episode of preterm labor or asymptomatic short cervix, or past medical history of preterm birth. Doppler flow and Pulsatility Index (PI) assessment of the umbilical artery, fetal middle cerebral artery, uterine arteries, and ductusvenosus were performed before and 72 h after vaginal progesterone administration.</p><p><strong>RESULTS:</strong> Results showed a significant reduction in the PI of the uterine artery following progesterone administration. Nevertheless, no significant changes were observed in the PI of other vessels. No significant difference was found in Doppler flow parameters in any of the examined vessels before or after progesterone treatment in women with Preterm Labor Pain (PLP). Yet, a statistically significant association was observed between short cervix complication in the current pregnancy and medical history of PLP in the previous pregnancy.</p><p><strong>CONCLUSION: </strong>Treatment with vaginal progesterone reduced the PI in the uterine arteries in the second and third trimesters of pregnancy. Thus, this medication may have useful vasodilatory effects on uterine-fetal vessels.</p>


2014 ◽  
Vol 44 (S1) ◽  
pp. 311-311
Author(s):  
B. Artunc Ulkumen ◽  
H. Pala ◽  
Y. Bulbul Baytur ◽  
F. Koyuncu

2014 ◽  
Vol 46 (16) ◽  
pp. 602-614 ◽  
Author(s):  
Yu-Qing Zhou ◽  
Lindsay S. Cahill ◽  
Michael D. Wong ◽  
Mike Seed ◽  
Christopher K. Macgowan ◽  
...  

This study used high-frequency ultrasound to evaluate the flow distribution in the mouse fetal circulation at late gestation. We studied 12 fetuses (embryonic day 17.5) from 12 pregnant CD1 mice with 40 MHz ultrasound to assess the flow in 11 vessels based on Doppler measurements of blood velocity and M-mode measurements of diameter. Specifically, the intrahepatic umbilical vein (UVIH), ductus venosus (DV), foramen ovale (FO), ascending aorta (AA), main pulmonary artery (MPA), ductus arteriosus (DA), descending thoracic aorta (DTA), common carotid artery (CCA), inferior vena cava (IVC), and right and left superior vena cavae (RSVC, LSVC) were examined, and anatomically confirmed by micro-CT. The mouse fetal circulatory system was found to be similar to that of the humans in terms of the major circuit and three shunts, but characterized by bilateral superior vena cavae and a single umbilical artery. The combined cardiac output (CCO) was 1.22 ± 0.05 ml/min, with the left ventricle (flow in AA) contributing 47.8 ± 2.3% and the right ventricle (flow in MPA) 52.2 ± 2.3%. Relative to the CCO, the flow percentages were 13.6 ± 1.0% for the UVIH, 10.4 ± 1.1% for the DV, 35.6 ± 2.4% for the DA, 41.9 ± 2.6% for the DTA, 3.8 ± 0.3% for the CCA, 29.5 ± 2.2% for the IVC, 12.7 ± 1.0% for the RSVC, and 9.9 ± 0.9% for the LSVC. The calculated flow percentage was 16.6 ± 3.4% for the pulmonary circulation and 31.2 ± 5.3% for the FO. In conclusion, the flow in mouse fetal circulation can be comprehensively evaluated with ultrasound. The baseline data of the flow distribution in normal mouse fetus serve as the reference range for future studies.


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