OP23.04: Rate of conversion of normal to abnormal umbilical, middle cerebral and uterine arteries in late-onset small-for-gestational-age fetuses

2009 ◽  
Vol 34 (S1) ◽  
pp. 136-136
Author(s):  
M. Munmany ◽  
F. Figueras ◽  
E. Meler ◽  
R. Cruz-Martinez ◽  
D. Oros ◽  
...  
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Late Onset ◽  
Uterine Arteries

Perinatal Outcome and its Prediction Using Longitudinal Feto-Maternal Doppler Follow-Up in Late Onset Small for Gestational Age Fetuses – A Prospective Cohort Study

2021 ◽  
Author(s):  
Silvia M. Lobmaier ◽  
Oliver Graupner ◽  
Javier U. Ortiz ◽  
Bernhard Haller ◽  
Christina Ried ◽  
...  
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Prospective Cohort ◽  
Perinatal Outcome ◽  
Late Onset ◽  
Induction Of Labor ◽  
University Hospital ◽  
Operative Delivery ◽  
Longitudinal Measurements ◽  
Cesarean Delivery Rate

Abstract Purpose To describe the perinatal outcome of a prospective cohort of late-onset small-for-gestational-age (SGA) fetuses and to test adverse perinatal outcome (APO) prediction using Doppler measurements. Methods Singleton pregnancies from 32 weeks with suspicion of SGA (followed-up each 2 weeks) and randomly selected healthy controls at a university hospital were included. The whole SGA group was divided into the FGR subgroup or SGA percentile 3–10 subgroup. The following Doppler measurements were evaluated prospectively: umbilical artery (UA) pulsatility index (PI), middle cerebral artery (MCA) PI, cerebro-placental ratio (CPR), and mean uterine artery (mUtA) PI. APO was defined as arterial cord blood pH ≤ 7.15 and/or 5-minute Apgar ≤ 7 and/or emergency operative delivery and/or admission to the neonatal unit. Induction of labor was indicated according to a stage-based protocol. Results A total of 149 SGA and 143 control fetuses were included. The number of operative deliveries was similar between both groups (control: 29 %, SGA: 28 %), especially the cesarean delivery rate after the onset of labor (11 % vs. 10 %). Most SGA cases ended up in induction of labor (61 % vs. 31 %, p < 0.001). The areas under the curve (AUC) for APO prediction were similar using the last UA PI, MCA PI, CPR, and mUtA PI and barely reached 0.60. The AUC was best for the FGR subgroup, using the minimal CPR or maximum mUtA PI z-score of all longitudinal measurements (AUC = 0.63). Conclusion SGA fetuses do not have a higher rate of operative delivery if managed according to a risk stratification protocol. Prediction of APO is best for SGA and FGR using the “worst” CPR or mUtA PI but it remains moderate.

scholarly journals Comparison of neonatal outcomes of small for gestational age and appropriate for gestational age preterm infants born at 28–36 weeks of gestation: a multicentre study in Ethiopia

2020 ◽  
Vol 4 (1) ◽  
pp. e000740
Author(s):  
Netsanet Workneh Gidi ◽  
Robert L Goldenberg ◽  
Assaye K Nigussie ◽  
Elizabeth McClure ◽  
Amha Mekasha ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Late Onset ◽  
Early Recognition ◽  
Neonatal Outcomes ◽  
P Value ◽  
Prolonged Hospitalisation ◽  
Increased Risk ◽  
Appropriate For Gestational Age

PurposeThe aim of this study was to assess morbidity and mortality pattern of small for gestational age (SGA) preterm infants in comparison to appropriate for gestational age (AGA) preterm infants of similar gestational age.MethodWe compared neonatal outcomes of 1336, 1:1 matched, singleton SGA and AGA preterm infants based on their gestational age using data from the study ‘Causes of Illness and Death of Preterm Infants in Ethiopia (SIP)’. Data were analysed using SPSS V.23. ORs and 95% CIs and χ2 tests were done, p value of <0.05 was considered statistically significant.ResultThe majority of the infants (1194, 89%) were moderate to late preterm (32–36 weeks of gestation), 763 (57%) were females. Male preterm infants had higher risk of being SGA than female infants (p<0.001). SGA infants had increased risk of hypoglycaemic (OR and 95% CI 1.6 (1.2 to 2.0), necrotising enterocolitis (NEC) 2.3 (1.2 to 4.1), polycythaemia 3.0 (1.6 to 5.4), late-onset neonatal sepsis (LOS) 3.6 (1.1 to 10.9)) and prolonged hospitalisation 2.9 (2.0 to 4.2). The rates of respiratory distress syndrome (RDS), apnoea and mortality were similar in the SGA and AGA groups.ConclusionNeonatal complications such as hypoglycaemic, NEC, LOS, polycythaemia and prolonged hospitalisation are more common in SGA infants, while rates of RDS and mortality are similar in SGA and AGA groups. Early recognition of SGA status, high index of suspicion and screening for complications associated and timely intervention to prevent complications need due consideration.

Low Serum Levels of HtrA3 at 15 Weeks of Gestation Are Associated with Late-Onset Preeclampsia Development and Small for Gestational Age Birth

2019 ◽  
Vol 46 (6) ◽  
pp. 392-401 ◽  
Author(s):  
Sonia Soo Yee Teoh ◽  
Yao Wang ◽  
Ying Li ◽  
Shalem Yiner-Lee Leemaqz ◽  
Gus A. Dekker ◽  
...  
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Late Onset ◽  
Serum Levels ◽  
Low Serum

Placental findings in late-onset small for gestational age births without Doppler signs of placental insufficiency and their impact in neurodevelopmental outcome

Placenta ◽  
2014 ◽  
Vol 35 (9) ◽  
pp. A38
Author(s):  
Alfons Nadal ◽  
Miguel Parra-Saavedra ◽  
Francesca Crovetto ◽  
Stefania Triunfo ◽  
Stefan Savchev ◽  
...  
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Late Onset ◽  
Neurodevelopmental Outcome ◽  
Placental Insufficiency

Comparison of cardiac morphology and function in small for gestational age fetuses and fetuses with late-onset fetal growth retardation

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Ezgi Turgut ◽  
Halis Özdemir ◽  
Gökçe Turan ◽  
Merih Bayram ◽  
Deniz Karcaaltincaba
Keyword(s):  
Fetal Growth ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Neonatal Intensive Care ◽  
Late Onset ◽  
Morphological Changes ◽  
Left Ventricular ◽  
Left Ventricular Wall ◽  
Control Group ◽  
Ventricular Wall

Abstract Objectives To compare cardiac structural and functional findings of fetuses with fetal growth restriction (FGR) and small for gestational age (SGA). Methods In this prospective cohort study, patients were classified into three groups using Delphi procedure according to fetal weight, umbilical, uterine artery Doppler and cerebroplacental ratio. Fetal cardiac ultrasonographic morphology and Doppler examination was performed to all pregnant women at 36 weeks of gestation. Results Seventy three patients were included in the study. There were one (6.7%) patient in the control group, 2 (13.3%) in the SGA group and 12 (80%) in the FGR group who needed neonatal intensive care unit (NICU) and NICU requirement was significantly higher in FGR fetuses (p<0.001). Left spherical index was found to be lower only among FGR fetuses (p=0.046). Left ventricular wall thickness was decreased and the right/left ventricular wall ratio was increased in FGR fetuses (p=0.006, p<0.001). Tricuspid/mitral valve ratio and mitral annular plane systolic excursion value was lower in FGR fetuses (p=0.034, p=0.024 respectively). Also, myocardial performance index was remarkably higher in FGR group (p=0.002). Conclusions We detected cardiac morphological changes in cases of both SGA and FGR—more pronounced in the FGR cases. Findings related to morphological changes on the left side in FGR cases were considered secondary to volume increase in FGR cases as an indicator of a brain-protective effect. In the FGR group, both systolic and diastolic dysfunctions were detected in the left heart.

scholarly journals Longitudinal changes in uterine, umbilical and fetal cerebral Doppler indices in late-onset small-for-gestational age fetuses

2010 ◽  
Vol 37 (2) ◽  
pp. 191-195 ◽  
Author(s):  
D. Oros ◽  
F. Figueras ◽  
R. Cruz-Martinez ◽  
E. Meler ◽  
M. Munmany ◽  
...  
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Late Onset ◽  
Longitudinal Changes ◽  
Doppler Indices
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