scholarly journals OP03.02: Diagnostic sensitivity and clinical value of prenatal ultrasound, post-mortem magnetic resonance imaging and conventional autopsy in structural fetal abnormality

2009 ◽  
Vol 34 (S1) ◽  
pp. 69-69
Author(s):  
A. Breeze ◽  
J. J. Cross ◽  
G. Hackett ◽  
F. Jessop ◽  
I. Joubert ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Prenatal Ultrasound ◽  
Diagnostic Sensitivity ◽  
Post Mortem ◽  
Resonance Imaging ◽  
Clinical Value ◽  
Fetal Abnormality ◽  
Conventional Autopsy

scholarly journals Post-Mortem 7.0-Tesla Magnetic Resonance Imaging of the Hippocampus in Progressive Supranuclear Palsy with and without Cerebral Amyloid Angiopathy

NeuroSci ◽  
2020 ◽  
Vol 1 (2) ◽  
pp. 115-120
Author(s):  
Jacques De Reuck ◽  
Florent Auger ◽  
Nicolas Durieux ◽  
Claude-Alain Maurage ◽  
Vincent Deramecourt ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Progressive Supranuclear Palsy ◽  
Cerebral Amyloid Angiopathy ◽  
Amyloid Angiopathy ◽  
Post Mortem ◽  
Resonance Imaging ◽  
Cerebral Amyloid ◽  
Magnetic Resonance Imaging Mri ◽  
Neuropathological Examination

Introduction and Purpose: Cerebral amyloid angiopathy (CAA) can be observed in patients with progressive supranuclear palsy (PSP), though to a lesser degree than in Alzheimer’s disease. The present post-mortem 7.0-tesla magnetic resonance imaging (MRI) evaluates whether CAA has an influence on the degree of hippocampal atrophy (HA) and on the incidence of associated micro-infarcts (HMIs) and cortical micro-bleeds (HMBs). Material and Methods: Eight brains with PSP-CAA were compared to 20 PSP brains without CAA. In addition to the neuropathological examination, the hippocampus was evaluated on the most representative coronal section with T2 and T2*-weighted MRI sequences. The average degree of HA was determined in both groups. The incidence of HMIs and HMBs was also compared as well as the frequency of cortical micro-infarcts (CoMIs) and cortical micro-bleeds (CoMBs) in the hemispheric neocortex. Results: The neuropathological examination showed a higher incidence of lacunar infarcts in the PSP-CAA brains compared to the PSP ones. With magnetic resonance imaging (MRI), the severity of HA and the incidence of HMIs and HMBs was similar between both groups. Additionally, the frequency of CoMIs and CoMBs in the neocortex was comparable. Conclusions: The association of CAA in PSP brains has no influence on the degree of HA and on the incidence of the small cerebrovascular lesions in the hippocampus as well as in the neocortex.

scholarly journals Comparison of conventional autopsy and magnetic resonance imaging in determining the cause of sudden death in the young

2014 ◽  
Vol 16 (1) ◽  
pp. 44 ◽  
Author(s):  
Rajesh Puranik ◽  
Belinda Gray ◽  
Helen Lackey ◽  
Laura Yeates ◽  
Geoffrey Parker ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Sudden Death ◽  
Resonance Imaging ◽  
Conventional Autopsy

scholarly journals Galloway-Mowat syndrome: Prenatal ultrasound and perinatal magnetic resonance imaging findings

2011 ◽  
Vol 50 (2) ◽  
pp. 212-216 ◽  
Author(s):  
Chih-Ping Chen ◽  
Shuan-Pei Lin ◽  
Yu-Peng Liu ◽  
Jeng-Daw Tsai ◽  
Chen-Yu Chen ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Prenatal Ultrasound ◽  
Imaging Findings ◽  
Resonance Imaging

scholarly journals Visualisation of fetal meconium on post-mortem magnetic resonance imaging scans: a retrospective observational study

2020 ◽  
Vol 9 (11) ◽  
pp. 205846012097054
Author(s):  
Georgia Hyde ◽  
Andrew Fry ◽  
Ashok Raghavan ◽  
Elspeth Whitby
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Signal Intensity ◽  
Interrater Reliability ◽  
Hepatic Flexure ◽  
Radiology Department ◽  
High Signal ◽  
Post Mortem ◽  
Resonance Imaging ◽  
Tertiary Referral Centre

Background Less invasive techniques for fetal post-mortems are increasingly used to correlate with parental wishes. With the use of post-mortem magnetic resonance imaging (MRI), normal appearance of the organs must be established. Purpose To investigate the after death appearance of the fetal meconium throughout gestation using the hyperintense appearance of meconium on T1 weighted MRI. Material and Methods This was a retrospective study that took place in a tertiary referral centre radiology department. Sixty-two fetal body post-mortem MRI scans (January 2014 to May 2018) between 12 and 41 weeks gestation were reviewed. Signal intensity of meconium at the rectum, sigmoid colon, splenic flexure and hepatic flexure was evaluated and correlated with gestational age. Interrater reliability was calculated. Results Meconium did not consistently have high signal intensity on T1 scans and was not always obvious. Rectal meconium had the highest intensity, and the more proximal the bowel the lower the intensity. The meconium had higher intensity at earlier gestations. Interrater reliability for rectal meconium gradings was excellent. Conclusion This study provides the first published primary research on the appearance of fetal meconium on post-mortem MRI. Overall, results were variable and suggest an alteration of bowel contents after death, but further investigation is needed to effectively inform practice.

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