scholarly journals OC22.09: Middle cerebral artery peak systolic velocities in twin-twin transfusion syndrome fetuses around the time of fetoscopic laser coagulation

2009 ◽  
Vol 34 (S1) ◽  
pp. 42-43
Author(s):  
L. Gucciardo ◽  
P. Klaritsch ◽  
P. Lewi ◽  
T. Van Mieghem ◽  
E. Done ◽  
...  
2020 ◽  
Vol 5 ◽  
pp. 53-59
Author(s):  
A. V. Tkachenko

Purpose of the study: determination and analysis of echographic and Doppler indicators during pregnancy with monochorionic biamniotic twins.Materials and methods. The study involved 198 pregnant women aged 18–38 years, who were divided into three clinical groups. The I (control) clinical group included 65 (32.8%) pregnant women with uncomplicated singleton pregnancy (OB); the II clinical group included 60 (30.3%) patients with bichorionic biamniotic twins (BHBA); Clinical group III included 73 (36.9%) women with pregnancy with monochorionic biamniotic twins (MCBA). In order to elucidate the differential diagnostic criteria and more detailed assessment of the pathogenetic factors of the development of twin overflow syndrome (SBP) in the III clinical group, two subgroups were identified: III-A subgroup, which included 21 (28.8%) pregnant women with MCBA with twins and signs SBP, and III-B subgroup, which included 52 (71.2%) pregnant women with MCBA twins and no signs of SBP.Results. The diagnosis of MCBA of twins was established by ultrasound examination at 6–8 weeks of gestation in 56 (76.7%) patients, after 8 weeks - in 17 (23.3%) patients. A complex of pathological manifestations detected during an ultrasound scan (a combination of polyhydramnios in one of the fetuses with oligohydramnios in the other, discordant fetal development (DRP) of more than 20%, no visualization of the bladder in the recipient fetus and / or the presence of a large bladder in the fetus - donor, a decrease in motor activity in a smaller fetus, characteristic changes in Doppler measurements in the fetal-placental and fetal vessels, signs of anemia in a smaller fetus, etc.), made it possible to diagnose SBP antenatally in 21 (28.8%) patients from the III clinical group, among them, 11 (52.4%) were diagnosed with stage I SBP (according to the classification of R. Quintero et al.), 8 (38.1%) - stage II SBP.In 2 (9.5%) patients in the II trimester of pregnancy, severe forms of rapidly progressing SBP with signs of a growing sequence of low and polyhydramnios, progressive deterioration of Doppler parameters in the umbilical cord arteries of both fetuses, with an increase in the peak blood flow velocity in the middle cerebral artery of donor fetuses were revealed. ascites in recipient fetuses. In these pregnant women, an attempt was made to perform laser coagulation of vascular anastomoses in the placenta under ultrasound navigation control at 16 (+5) and 18 (+3) weeks of gestation. However, pregnancy ended in premature birth at 24 (2) and 25 (+4) weeks and was accompanied by intrauterine death of one smaller fetus (in 1 case) and early neonatal death of a large fetus (in another case).With MCBA twins not burdened with SBP, the mean values ​​of anthropometric parameters of both fetuses did not differ significantly. At the same time, in the presence of SBP, the biometric indicators of the donor fetus were probably lower relative to fetus A (this same subgroup), and when compared with similar anatomical indicators of fetuses in pregnant women of III-B subgroup. This clearly confirms the likelihood of the effect of progressive SBP on fetal growth rates and an increased risk of IGR and chronic distress (especially in donor fetuses).Conclusion. Complex ultrasound and Doppler assessment of uteroplacental-fetal blood flow in multiple pregnancies is an objective tool that allows to establish prognostic and diagnostic criteria for the development of obstetric complications, fetal disorders and perinatal outcomes. Prognostically unfavorable for the development of obstetric and perinatal complications associated with the formation of IGR and DRP in MCBA twins are early detection of a decrease in the diastolic component of blood flow, a significant increase in ADV, PI and IR in the umbilical cord arteries and aorta of fetuses in the dynamics of the II and III trimesters (p<0 ,05).The combination of an increase in peripheral vascular resistance with the centralization of blood circulation is manifested by violations of hemodynamic parameters in the middle cerebral artery of the fetus, which is typical in the case of the development of SBP in fetuses with MCBA of twins.


Author(s):  
John T. Dodge ◽  
John A. Bevan

Unlike many peripheral vascular beds, the sympathetic nervous system exerts little control on cerebral blood flow. The contractile response of isolated rabbit middle cerebral artery (MCA) segments to electrical field stimulation of its intramural nerves is less than in a similar-sized artery from the ear. This study was undertaken to characterize and compare the perivascular neuromuscular relationships and innervation density of similar-sized arteries varying in diameter from these two different regional arterial beds to see if there were structural correlates for these functional differences.


2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S217-S217
Author(s):  
Kentaro Deguchi ◽  
Mikiro Takaishi ◽  
Takeshi Hayashi ◽  
Atsuhiko Oohira ◽  
Shoko Nagotani ◽  
...  

Skull Base ◽  
2007 ◽  
Vol 17 (S 2) ◽  
Author(s):  
Veysel Bikmaz ◽  
Celal Iplikcioglu ◽  
Erdinc Ozek ◽  
Cem Dinc ◽  
Ozenc Minareci

Author(s):  
Yu. O. Novikov ◽  
I. E. Salakhov

Introduction. According to the defi nition of the World Health Organization (WHO), tension-type headache (TTH) is the most common type of primary headache. Rehabilitation of patients with chronic tension-type headache continues to be an important socio-medical problem. Its main goal is the most complete restoration of the functions of the musculoskeletal system of the neck, the correction of vascular and psychoemotional problems, and the patient′s return to his everyday life and work. As a rule, the main emphasis in the treatment of such patients is placed primarily on drug therapy. At the same time, practitioners are faced with a number of problems — the low effectiveness of the treatment, the nonpersistency of the results, allergic reactions, polypharmacy and others. All this suggests that there is a need for differentiated rehabilitation treatment of patients with tension-type headache with the use of various non-pharaceutical methods. The goal of research — to evaluate the clinical effi cacy of complex non-drug therapy in patients with tension-type headache.Materials and methods. The prospective controlled randomized study, which was conducted from October 2017 to March 2019 at the Department of Medical Rehabilitation of the Bashkir State Medical University, included 110 patients with TTH from the age of 20 to 45 years. All patients, depending on the treatment methodology used, were randomly divided into two groups of 55 people. Patients of the main group received complex rehabilitation treatment with the use of non-drug methods: osteopathic correction, acupuncture and exercise therapy. Patients in the control group received treatment in accordance with the standard of medical care for TTH (analgesics, non-steroidal antiinfl ammatory drugs, antidepressants, vasoactive and nootropic drugs). The study of the clinical effectiveness of the therapy included: an assessment of the severity of pain with the use of a visual analogue scale and a tensoalgimeter, a goniometric study with an assessment of the volume of active movements in the cervical spine, transcranial ultrasound dopplerography with an assessment of quantitative indicators in the system of the middle cerebral artery.Results. The use of complex non-drug therapy in patients with TTH compared with standard drug therapy leads to a signifi cantly more important decrease in the severity of pain, an increase in pain threshold, an increase in the volume of active movements in the cervical spine. The effect of non-drug treatment methods on blood fl ow in the system of the middle cerebral artery is comparable in its effectiveness with the use of pharmaceutical drugs.Conclusion. The proposed complex rehabilitation treatment of patients with TTH with the use of non-drug methods has shown clinical effi cacy which is comparable, and in a number of indicators, superior to the effectiveness of conventional medical treatment. All this determines the necessity of wider implementation of multidisciplinary non-drug treatment of patients with this pathology.


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