Late onset of ultrasound abnormalities in a case of periconceptional congenital cytomegalovirus infection

2008 ◽  
Vol 31 (4) ◽  
pp. 481-483 ◽  
Author(s):  
O. Picone ◽  
C. Vauloup-Fellous ◽  
A. G. Cordier ◽  
L. Grangeot-Keros ◽  
R. Frydman ◽  
...  
Keyword(s):  
Cytomegalovirus Infection ◽  
Late Onset ◽  
Congenital Cytomegalovirus Infection ◽  
Congenital Cytomegalovirus

Late onset and reactivation of chorioretinitis in children with congenital cytomegalovirus infection

1994 ◽  
Vol 13 (12) ◽  
pp. 1139-1142 ◽  
Author(s):  
SURESH BOPPANA ◽  
CATHERINE AMOS ◽  
WILLIAM BRITT ◽  
SERGIO STAGNO ◽  
CHARLES ALFORD ◽  
...  
Keyword(s):  
Cytomegalovirus Infection ◽  
Late Onset ◽  
Congenital Cytomegalovirus Infection ◽  
Congenital Cytomegalovirus

scholarly journals Contribution of Congenital Cytomegalovirus Infection to Permanent Hearing Loss in a Highly Seropositive Population: The Brazilian Cytomegalovirus Hearing and Maternal Secondary Infection Study

2019 ◽  
Author(s):  
Aparecida Y Yamamoto ◽  
Adriana R T Anastasio ◽  
Eduardo T Massuda ◽  
Myriam L Isaac ◽  
Alessandra K S Manfredi ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Cytomegalovirus Infection ◽  
Late Onset ◽  
Secondary Infection ◽  
Prevalence Ratio ◽  
Cost Effective ◽  
Congenital Cytomegalovirus Infection ◽  
Congenital Cytomegalovirus ◽  
Newborn Hearing

Abstract Background The exact contribution of congenital cytomegalovirus infection (cCMVI) to permanent hearing loss (HL) in highly seropositive populations is unknown. We determined the contribution of cCMVI to HL and estimated the effectiveness of newborn hearing screening (HS) in identifying neonates with CMV-related HL. Methods A total of 11 900 neonates born from a population with ≥97% maternal seroprevalence were screened for cCMVI and HL. cCMVI was confirmed by detection of CMV-DNA in saliva and urine at age <3 weeks. Results Overall, 68 (0.6%; 95% confidence interval [CI], 0.4–0.7) neonates were identified with cCMVI. Of the 91 (0.8%) newborns who failed the HS, 24 (26.4%) were confirmed with HL, including 7 (29.2%; 95% CI, 17.2–59.3) with cCMVI. Another newborn with cCMVI passed the HS but was confirmed with HL at age 21 days. Of the 62 neonates with cCMVI who underwent a complete hearing evaluation, 8 (12.9%; 95% CI, 6.7–23.4) had HL and most (7/8; 87.5%; 95% CI, 46.6–99.7) were identified by HS. The rate of CMV-related HL was 8 per 11 887 neonates (0.7 per 1000 live births). The prevalence ratio of HL among neonates with cCMVI compared to CMV-uninfected neonates was 89.5 (95% CI, 39.7–202.0). No late-onset cCMVI-related HL was detected during a median follow-up of 36 months. Conclusions cCMVI is an important cause of HL in childhood in all settings. Integrating targeted cCMVI screening among neonates who fail a HS could be a reasonable, cost-effective strategy to identify newborns with early-onset cCMVI-related HL.

scholarly journals Congenital cytomegalovirus infection and its impact on the auditory function

2019 ◽  
Vol 11 (3) ◽  
pp. 83-89
Author(s):  
R. A. Ivanova ◽  
M. Yu. Boboshko ◽  
E. S. Garbaruk ◽  
S. M. Vikhnina ◽  
V. V. Vasiliev ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Cytomegalovirus Infection ◽  
Comparison Group ◽  
Late Onset ◽  
Main Group ◽  
Sensorineural Hearing ◽  
Congenital Cytomegalovirus Infection ◽  
Congenital Cytomegalovirus

Congenital cytomegalovirus infection contributes substantially to the incidence of sensorineural hearing loss, which may be late-onset, progressive or fluctuating. It leads to delayed diagnostics of hearing impairments in children. The aim is to assess the frequency and time of hearing loss occurrence in children with congenital cytomegalovirus infection and to develop the audiological follow-up algorithm adapted for those children. Materials and methods: 60 children with verified congenital cytomegalovirus infection have been involved into research as the main group. 61 children, with other sensorineural hearing loss risk factors, but excluding congenital cytomegalovirus, were included into the comparison group. The age of children ranged from 2 months to 7 years old. The follow-up duration was up to 4 years. Audiological assessment included: auditory brainstem response, auditory steady state response, otoacoustic emissions, impedancometry, pure tone audiometry (its type depended on the children’s age and development level) and speech tests. Results: Hearing loss was revealed in 17% of the main group, it varied from mild to severe degree. Among these children 30% developed late-onset hearing loss. 5% of children of the comparison group were identified with congenital hearing loss. Assessment of central auditory pathways function has been performed in children elder than 4 years old: 70% of children of the main group and 10% of children of the comparison one were identified with auditory processing disorders. The received data may be used by otolaryngologists, audiologists, pediatricians and infectious diseases physicians. The developed follow-up admits timely diagnostics of sensorineural hearing loss in children with congenital cytomegalovirus.

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