scholarly journals OC203: Carotid artery blood volume flow and elevated blood pressure in high-risk pregnancy

2003 ◽  
Vol 22 (S1) ◽  
pp. 55-55
Author(s):  
M. O. Thompson ◽  
N. C. Wathen ◽  
K. Harrington
Author(s):  
Bharat Sejoo ◽  
Rajendra Bhati ◽  
Ajay Mathur ◽  
Prakash Keswani ◽  
Shrikant Sharma ◽  
...  

Background: The physiological changes in pregnancy may serve to protect the mother from the hazard of bleeding imposed by placentation and delivery, but they also carry the risk of an exaggerated response, localized or generalized, to coagulant stimuli. After correlating the trends of coagulation profile in all three trimesters of pregnancy with parameters [Body Mass Index (BMI), Glycemic status, Blood Pressure Status];  We can find out high risk pregnancies so that special attention can be given during pregnancy, labour and postpartum period. Material & Methods: A observational prospective analytic study done on 100 Pregnant ladies who were visited to routine antenatal clinic in the department of Obstetrics & Gynecological SMS Medical College and attached group of hospitals, on outdoor basis were selected in their first trimester (after 8 week gestation) in SMS medical college & attached group of hospitals during April 2017 to March 2018. The study protocol was approved by the Institutional Ethics Committee. All participants submitted informed consent before enrolment. After taking proper history, all the subjects underwent clinical examination comprising of general physical examination, assessment of vital parameters and systemic examination. Results: Our study that the mean age of study subjects was 26.46 ± 3.34 years. There was significant but weak positive correlation of D Dimer with BMI and Blood sugar in all trimesters of pregnancy. Significant correlation was found between APLA with DBP and MAP in 1st trimester of pregnancy. No correlation was found between APLA and other parameters in any trimester of pregnancy. Conclusion: We concluded that there were increased in FDP, D-Dimer, INR, APLA while platelets count, PT and aPTT were decreased.  Further prospective study will be required to measure the outcome of pregnancy so we can define a high-risk pregnancy and those will get special attention in peripartum period. Keywords: Trimester, Pregnancy, D Dimer, BMI, Blood pressure, Correlation


2013 ◽  
Vol 21 (3) ◽  
pp. 726-733 ◽  
Author(s):  
Nilba Lima de Souza ◽  
Ana Cristina Pinheiro Fernandes de Araújo ◽  
Iris do Ceu Clara Costa

OBJECTIVE: To identify the meanings attributed by mothers to hypertensive disorders of pregnancy (HDPs) and their consequences, such as premature birth and hospitalization of the infant in the neonatal intensive care unit (NICU). METHOD: A qualitative study, based on the Central Nucleus Theory, with 70 women who had hypertensive disorders of pregnancy and preterm delivery. We used the technique of free word association (FWAT) with three stimuli: high blood pressure during pregnancy, prematurity and NICU. RESULTS: We obtained 1007 evocations, distributed as follows: high blood pressure during pregnancy (335) prematurity (333) and NICU (339). These constituted three thematic units: representation of HDPs, prematurity and the NICU. The categories death and negative aspects were inherent to the three units analyzed, followed by coping strategies and needs for care present in HDPs and prematurity. CONCLUSION: The study had death as its central nucleus, and highlighted the subjective aspects present in the high risk pregnancy and postpartum cycle. It is hoped that this research will contribute to qualifying nursing care for women confronting the problem of HDPs, so that they can cope with less impacts from the adverse effects of high risk pregnancy and birth.


2019 ◽  
Author(s):  
YunLei Wang ◽  
Tong Zhang ◽  
YuGe Zhang ◽  
Yan Yu ◽  
Fan Bai ◽  
...  

AbstractObjectiveThe objective was to investigate the effects of shift-work (SW) on the carotid arteries.MethodsThis study used two inverted photoperiods (inverted light:dark [ILD]16:8 and ILD12:12) to create the SW model. We recorded the rhythm and performed serological tests, carotid ultrasound, magnetic resonance imaging, and carotid biopsy.ResultsSW induced elevated blood pressure and increased angiotensin-II, apolipoprotein E, blood glucose, and triglycerides. SW increased the carotid intima-media thickness. SW led to the development of carotid arterial thrombosis, reduced cerebral blood flow, and increased the number of collagen fibers, expression of angiotensin receptor and low-density lipoprotein receptor in the carotid arteries. SW decreased 3-hydroxy-3-methylglutaryl-CoA reductase and nitric oxide. SW induced the atherosclerotic plaque in the aorta. Multiple results of SHR were worse than WKY rats.ConclusionSW can induce metabolic disorders and elevated blood pressure. SW can cause intima-media thickening of the carotid artery and aorta atherosclerosis. SW may result in carotid arterial thrombosis and affect cerebral blood flow. Hypertension can aggravate the adverse effects of SW.


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