scholarly journals OC18.09: Splenic vessels: runway lights to spot the fetal pancreas

2021 ◽  
Vol 58 (S1) ◽  
pp. 55-55
Author(s):  
D. Singh ◽  
L. Kaur
Keyword(s):  
Fetal Pancreas ◽  
Splenic Vessels

DEVELOPMENT OF ISOLOGOUS TRANSPLANTS OF CELL SUSPENSIONS OF THE FETAL PANCREAS IN THE RAT

1974 ◽  
Vol 77 (1_Suppl) ◽  
pp. S97 ◽  
Author(s):  
K. H. Usadel ◽  
U. Schwedes ◽  
U. Leuschner ◽  
K. Schöffling
Keyword(s):  
Cell Suspensions ◽  
Fetal Pancreas

Growth and hormonal content of human fetal pancreas passaged in athymic mice

Diabetes ◽  
1986 ◽  
Vol 35 (4) ◽  
pp. 464-469 ◽  
Author(s):  
B. E. Tuch ◽  
S. Grigoriou ◽  
J. R. Turtle
Keyword(s):  
Athymic Mice ◽  
Fetal Pancreas ◽  
Human Fetal Pancreas ◽  
Hormonal Content

Successful long-term cryopreservation and transplantation of human fetal pancreas

Diabetes ◽  
1989 ◽  
Vol 38 (4) ◽  
pp. 448-453 ◽  
Author(s):  
D. A. Hullett ◽  
K. P. Bethke ◽  
A. S. Landry ◽  
D. K. Leonard ◽  
H. W. Sollinger
Keyword(s):  
Fetal Pancreas ◽  
Human Fetal Pancreas

Microfilm study of cultures of islet cells of the bovine fetal pancreas

1978 ◽  
Vol 85 (2) ◽  
pp. 204-207
Author(s):  
V. N. Blyumkin ◽  
R. A. Babikova ◽  
I. N. Kokorin
Keyword(s):  
Islet Cells ◽  
Fetal Pancreas

scholarly journals Clinical Relevance Between Survival Outcomes and Invasion of Splenic Vessels in Pancreatic Body or Tail Adenocarcinoma

HPB ◽  
2021 ◽  
Vol 23 ◽  
pp. S64
Author(s):  
J.S. Kang ◽  
Y.J. Choi ◽  
Y. Byun ◽  
Y. Han ◽  
E. Kim ◽  
...  
Keyword(s):  
Clinical Relevance ◽  
Survival Outcomes ◽  
Pancreatic Body ◽  
Splenic Vessels

scholarly journals EARLY HUMAN FETAL PANCREAS AS A THERAPY FOR DIABETES

2008 ◽  
Vol 86 (Supplement) ◽  
pp. 561
Author(s):  
B Tuch ◽  
W Wu ◽  
K Brands ◽  
E Colvin ◽  
J Sung ◽  
...  
Keyword(s):  
Fetal Pancreas ◽  
Human Fetal Pancreas ◽  
Early Human

Transforming growth factor-alpha (TGF-alpha) and insulin gene expression in human fetal pancreas

Development ◽  
1992 ◽  
Vol 114 (4) ◽  
pp. 833-840 ◽  
Author(s):  
P.J. Miettinen ◽  
K. Heikinheimo
Keyword(s):  
Growth Factor ◽  
Beta Cells ◽  
Copy Number ◽  
Transforming Growth Factor ◽  
Insulin Antibody ◽  
Transforming Growth Factor Alpha ◽  
Double Labeling ◽  
Fetal Pancreas ◽  
Insulin Mrna ◽  
Factor Alpha

Transforming growth factor-alpha (TGF-alpha) mRNA is expressed in several pancreatic cancer cell lines, but its expression during normal fetal pancreas development has not been studied. We investigated the expression of TGF-alpha, its receptor (EGF-R) and insulin mRNA and their corresponding peptides in human fetal pancreata (15–20 gestation weeks). Polymerase chain reaction (PCR) and RNAase protection analysis revealed that TGF-alpha and insulin mRNAs were detectable in pancreas during the developmental span studied. In northern blot analysis a single band of 4.8 kilobases (kb) corresponding to the TGF-alpha transcript and a 0.6 kb for the insulin mRNA were detected in the pancreas. Using in situ hybridization, TGF-alpha mRNA expression was seen in a low copy number in both the exo- and endocrine pancreas. By immunohistochemistry TGF-alpha-immunoreactive cells were detected in the ducts, acini and islets showing that the mRNA was translated into protein. By contrast, insulin transcripts were detected in a high copy number, restricted to the islets of Langerhans. However, monoclonal insulin antibody detected less insulin containing cells than could be expected from the mRNA pattern suggesting that fetal beta-cells rapidly secrete insulin instead of storing it in the secretory granules. Alternatively, the translation of insulin mRNA could be inefficient. By double labeling the pancreas sections with polyclonal TGF-alpha antiserum and monoclonal insulin antibody the TGF-alpha- and insulin-like immunoreactivity was localized to beta-cells. Furthermore, mRNA for the TGF-alpha receptor, EGF-R, together with EGF-R-immunoreactive cells were also present in pancreas.(ABSTRACT TRUNCATED AT 250 WORDS)

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