scholarly journals OC04.07: Adjusting growth standards for fetal sex better correlates with perinatal morbidity and mortality: an Australian state‐wide population study

2021 ◽  
Vol 58 (S1) ◽  
pp. 12-12
Author(s):  
N. Pritchard ◽  
S.P. Walker ◽  
S. Tong ◽  
A. Lindquist
Keyword(s):  
Population Study ◽  
Morbidity And Mortality ◽  
Perinatal Morbidity ◽  
Fetal Sex ◽  
Growth Standards ◽  
Australian State ◽  
Wide Population

scholarly journals Adjusting growth standards for fetal sex improves correlation of small babies with stillbirth and adverse perinatal outcomes: A state-wide population study

2021 ◽  
Author(s):  
Natasha Pritchard ◽  
Susan Walker ◽  
Stephen Tong ◽  
Anthea C. Lindquist
Keyword(s):  
Gestational Age ◽  
Perinatal Outcomes ◽  
Adverse Outcomes ◽  
Fetal Sex ◽  
Growth Standards ◽  
Increased Risk ◽  
Appropriate For Gestational Age ◽  
Adverse Perinatal Outcomes ◽  
Wide Population ◽  
High Risk Cohort

Objective: Identify the proportion of infants reclassified if sex-specific birthweight charts were used, and if this reclassification has an impact on the correlation between birthweight centile and adverse perinatal outcome. Design: Retrospective cohort study Setting: Victoria, Australia. Population: All infants born from 2005-2015 (529,261) Methods: We applied GROW centiles, either adjusted or unadjusted for fetal sex. We compared proportions of small for gestational age (SGA, <10th centile) infants, then the populations of males considered small only by sex-specific charts and females considered small only by unadjusted charts. Main Outcome Measures: Stillbirth, combined perinatal mortality, NICU admissions, Apgars <7 at 5 minutes, emergency caesarean sections. Results: Of those <10th centile by unadjusted charts, 39.6% were male, and 60.5% female. Using sex-specific charts, 50.3% <10th centile were male and 49.7% female. 9,449 (19.2%) females that were SGA according to unadjusted charts were appropriate for gestational age (AGA,>10th-<90th centile) using sex-specific charts. These reclassified newborn females were not at increased risk of adverse outcomes compared with an AGA infant, but were at increased risk of being iatrogenically delivered for suspected growth restriction (RR 4.90, 95%CI 4.39–5.48). 8,048 male infants were reclassified as SGA by sex-specific charts (25% SGA increase). Compared with AGA infants, these reclassified male newborns were at greater risk of stillbirth (RR 1.94, 95%CI 1.30-2.90) and all other adverse perinatal outcomes. Conclusions: Sex-specific growth standards classify a new high-risk cohort of male infants as SGA, and exclude a cohort of females, whose risk is no greater than appropriately grown infants.

Medically indicated late preterm delivery and its impact on perinatal morbidity and mortality: a retrospective population-based cohort study

2018 ◽  
Vol 32 (19) ◽  
pp. 3278-3287 ◽  
Author(s):  
Limor Besser ◽  
Liat Sabag-Shaviv ◽  
Maayan Yitshak-Sade ◽  
Salvatore Andrea Mastrolia ◽  
Danielle Landau ◽  
...  
Keyword(s):  
Cohort Study ◽  
Preterm Delivery ◽  
Population Based ◽  
Late Preterm ◽  
Morbidity And Mortality ◽  
Perinatal Morbidity

Modern concepts of etiology, pathogenesis and risk factors for preeclampsia

2021 ◽  
Vol 70 (5) ◽  
pp. 105-116
Author(s):  
Maria Yu. Abramova ◽  
Mikhail I. Churnosov
Keyword(s):  
Risk Factors ◽  
Social Issue ◽  
Chronic Diseases ◽  
Molecular Mechanisms ◽  
Current Understanding ◽  
Morbidity And Mortality ◽  
Perinatal Morbidity ◽  
Distant Future

Preeclampsia is a serious complication of pregnancy and complicates its course in 2-8% of all cases. According to the literature, the disease is associated with an increase in maternal and perinatal morbidity and mortality, and is a predictor of the development of chronic diseases in the distant future, which is an important medical and social issue. Of particular interest is the study of the molecular mechanisms of etiopathogenesis and risk factors for preeclampsia, which, unfortunately, are currently poorly studied and understood, thus dictating the need for further study of this complication of pregnancy. This article discusses the current understanding of the etiology, pathogenesis and risk factors for preeclampsia.

scholarly journals Editorial–Special Issue

2016 ◽  
Vol 19 (3) ◽  
pp. 167-167 ◽  
Author(s):  
Mark P. Umstad ◽  
Ricardo Palma-Dias ◽  
Asma Khalil
Keyword(s):  
Well Being ◽  
Morbidity And Mortality ◽  
Perinatal Morbidity ◽  
Special Issue ◽  
Monochorionic Twin ◽  
Editorial Special Issue ◽  
Twin Pregnancies

Monochorionic twin pregnancies are subject to unique complications that can threaten the life and well-being of both fetuses, resulting in a disproportionate increase in perinatal morbidity and mortality.

scholarly journals Maternal and fetal outcome in oligohydramnios after 34 weeks of gestation

2018 ◽  
Vol 7 (11) ◽  
pp. 4604
Author(s):  
Mahantappa A. Chiniwar ◽  
Joe Kaushik M. ◽  
Sharada B. Menasinkai
Keyword(s):  
Amniotic Fluid ◽  
Fetal Outcome ◽  
Morbidity And Mortality ◽  
Research Centre ◽  
Control Group ◽  
P Value ◽  
Study Group ◽  
Perinatal Morbidity ◽  
Amniotic Fluid Index ◽  
Chi Square

Background: Oligohydramnios is one of the major causes of maternal and perinatal morbidity and mortality. It is a clinical condition characterized by Amniotic Fluid Index (AFI) ≤5 cm by sonographic assessment. The aim of present study is to know the maternal and fetal outcome in oligohydramnios after 34 weeks of gestation compared with women who had normal volume of amniotic fluid.Methods: Study was done for the period of 21 months from November 2014-July 2016 at Adichunchanagiri Institute of Medical Sciences, Hospital and Research Centre Bellur. 50 antenatal cases with > 34 weeks of gestation with AFI ≤5 cm by ultrasonographic estimation were included as study group and 50 women with normal AFI were included as control group. Maternal and fetal outcome of the women with oligohydramnios were analyzed and compared with control group.Results: Results were analyzed statistically using parameters like mean, SD, Chi Sq test, P value. Amniotic fluid was clear in 32% in study and 78% in control group, thin meconium stained in 30% in study group and 14%in control group and was thick meconium stained in 38% in study group and 8% in control group (Chi square =22.31, p<0.0001). Induction of labour was done in 54% in study group and 20% in control group. Cesarean delivery was done in 58% in study group women and 28% in control group women. Regarding the birth weight of babies 62% were < 2.5 kg in study group and 18% in control group with p<0.001. 10% of babies in study group required NICU admission and perinatal mortality was 2%.Conclusions: Due to increased perinatal morbidity and mortality and increased rate of LSCS, timely decision during labour is important to reduce perinatal morbidity and mortality.

Association of Ureaplasma Urealyticum in the Placenta with Perinatal Morbidity and Mortality

1985 ◽  
Vol 40 (1) ◽  
pp. 21-22
Author(s):  
RUTH B. KUNDSIN ◽  
SHIRLEY G. DRISCOLL ◽  
RICHARD R. MONSON ◽  
CHING YEH ◽  
STELLA A. BIANO ◽  
...  
Keyword(s):  
Ureaplasma Urealyticum ◽  
Morbidity And Mortality ◽  
Perinatal Morbidity

scholarly journals Influence of the Human Development Index on the Maternal–Perinatal Morbidity and Mortality of Pregnant Women with SARS-CoV-2 Infection: Importance for Personalized Medical Care

2021 ◽  
Vol 10 (16) ◽  
pp. 3631
Author(s):  
Yolanda Cuñarro-López ◽  
Santiago García-Tizón Larroca ◽  
Pilar Pintado-Recarte ◽  
Concepción Hernández-Martín ◽  
Pilar Prats-Rodríguez ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Human Development ◽  
Human Development Index ◽  
Maternal Morbidity ◽  
Tertiary Care ◽  
Country Of Origin ◽  
Morbidity And Mortality ◽  
Inverse Association ◽  
Perinatal Morbidity ◽  
Development Index

Coronavirus disease-19 (COVID-19) is perhaps the most worrisome pandemic in the 21st century, having entailed devastating consequences for the whole society during the last year. Different studies have displayed an existing association between pregnancy and COVID-19 severity due to the various physiological changes that occur during gestation. Recent data identified maternal country of origin as an important determinant of COVID-19 presentation in pregnant women. However, the explanation of this fact remains to be fully elucidated. Therefore, the purpose of this work is to analyze the possible relationship between Human Development Index (HDI) of maternal country of origin with the morbimortality of pregnant women and their newborns. Here, we conducted a multicentric, ambispective, observational case-control study (1:1 ratio) and compare with the HDI of each country (group 1—very high HDI, group 2—high HDI, group 3—medium HDI, and group 4—low HDI). In total, 1347 pregnant women with confirmed SARV-CoV-2 infection (cases) were enrolled, and each was paired with one control to give a total number of 2694 participants from 81 tertiary care centers. Among the women with SARS-CoV-2 infection, more cases were produced of perinatal mortality, overall maternal morbidity, COVID-19 maternal morbidity, C-sections, hypertensive maternal morbidity, and perinatal morbidity. Our results described an inverse association between HDI and maternofetal morbidity and mortality. Moreover, the countries with an HDI lower than 1 showed higher rates of patients with maternal COVID-19-related morbidity (6.0% vs. 2.4%, p < 0.001), a need for oxygen therapy (4.7% vs. 1.8%, p < 0.001), and maternal ICU admission (2.6% vs. 1.0%, p = 0.007). Compared to other risk factors such as overweight, obesity, preexisting and obstetric comorbidities, HDI emerged as an independent risk factor explaining much of the increased maternal–perinatal morbidity and mortality detected in our group of cases. Further research is needed to establish to confirm the real impact of this factor and its components on pregnancy outcomes.

scholarly journals EFFECTIVENESS AND SAFETY DIFFERENCES OF ISOXSUPRINE AND NIFEDIPINE AS TOCOLYTICS IN THE RISK OF PRETERM LABOR

2017 ◽  
Vol 53 (4) ◽  
pp. 242
Author(s):  
Nur Oktavia ◽  
Yulistiani Yulistiani ◽  
Unedo H Markus ◽  
Hendriette Irene Mamo
Keyword(s):  
Observational Study ◽  
Preterm Labor ◽  
Morbidity And Mortality ◽  
Perinatal Morbidity ◽  
Premature Labor ◽  
The Difference

Premature labor is a cause of high rates of perinatal morbidity and mortality. The use of tocolytics is one of the efforts to handle the risk of preterm labor. Tocolytics which are widely used in Indonesia is isoxsuprine and nifedipine. The purpose of this study was to identify the difference of effectiveness and safety of isoxsuprine as tocolytics in the risk of preterm labor. This was an observational study in the form of a case study that was done in detail and depth to the patients who were diagnosed as imminent preterm labor. In conclusion, there were differences in the effectiveness and safety of isoxsuprine and nifedipine as tocolytics in the risk of preterm labor.

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