scholarly journals VP52.19: Long‐term effect of prenatal progesterone exposure in offspring development, behaviour and health: a systematic review and meta‐analysis

2020 ◽  
Vol 56 (S1) ◽  
pp. 299-299
Author(s):  
N. Simons ◽  
M. Leeuw ◽  
J. `T Hooft ◽  
J. Limpens ◽  
M. Oudijk ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Term Effect ◽  
Offspring Development ◽  
Long Term Effect

scholarly journals Does gamification improve physical activity? A systematic review and meta-analysis

2020 ◽  
Author(s):  
Alexandre Mazéas ◽  
Martine Duclos ◽  
Bruno Pereira ◽  
Aïna Chalabaev
Keyword(s):  
Physical Activity ◽  
Systematic Review ◽  
Chronic Diseases ◽  
Video Game ◽  
Meta Analysis ◽  
Term Effect ◽  
Sensitivity Analyses ◽  
Control Group ◽  
Long Term Effect

Background. The use of gamification to change behaviors and promote physical activity is a promising avenue to tackle the global physical inactivity pandemic and the current prevalence of chronic diseases. However, we do not have yet evidence of the effectiveness of gamified interventions with the existence of mixed results in the literature.Objective. This systematic review and meta-analysis aimed to evaluate the effectiveness of gamified interventions and their healthcare potential by testing the scalability and sustainability of their influence on physical activity (PA) and sedentary behaviors (SB).Methods. Five electronic databases (Pubmed, EMBASE, Scopus, Web of Science and CENTRAL) were searched for randomized controlled trials (RCTs) published since 2010. Eligibility criteria were based on components of PICO (participants, interventions, comparators, and outcomes). Studies were included when they used gamified interventions in daily life with an active or inactive control group, and when they assessed a PA or SB outcome. Studies were excluded when the intervention was based on an active video game using a gaming console. We conducted meta-analyses using a random effects model approach. Sensitivity analyses, influence analyses and publication bias analyses were performed to examine the robustness of our results.Results. The main meta-analysis performed on 16 studies and 2407 participants, revealed a small to medium summary effect of gamified interventions on PA behavior (g = 0.42 (95%CI [0.14, 0.69]). No statistical difference was found between different subgroups (adults vs adolescents, healthy participants vs adults with chronic diseases) and no interaction effects with moderators like age, gender or BMI, suggesting good scalability of gamified interventions. Moreover, the effect appears better on the step count (MD = +1609.56 steps per day (95%CI [372.39, 2846.73]) than on moderate-to-vigorous PA (g = 0.31 (95%CI [-0.19, 0.80]). The long-term effect (measured with follow-up averaging 14 weeks after the end of the intervention) is more volatile with a very small to small effect (g = 0.15, [0.07, 0.23]). Conclusions. This meta-analysis confirms that gamified interventions are promising to promote PA in various publics. However, if the effect persists after the end of the program, suggesting that it is not just a novelty effect due to the playful nature of gamification, it seems volatile with a small long-term effect. The integration of gamification in more global healthcare interventions could be a way to address this low sustainability. Future rigorous trials are needed to explore these perspectives.

Does gamification improve physical activity? A systematic review and meta-analysis (Preprint)

2020 ◽  
Author(s):  
Alexandre Mazeas ◽  
Martine Duclos ◽  
Bruno Pereira ◽  
Aïna Chalabaev
Keyword(s):  
Physical Activity ◽  
Systematic Review ◽  
Chronic Diseases ◽  
Video Game ◽  
Meta Analysis ◽  
Term Effect ◽  
Sensitivity Analyses ◽  
Control Group ◽  
Long Term Effect

BACKGROUND The use of gamification to change behaviors and promote physical activity is a promising avenue to tackle the global physical inactivity pandemic and the current prevalence of chronic diseases. However, we do not have yet evidence of the effectiveness of gamified interventions with the existence of mixed results in the literature. OBJECTIVE This systematic review and meta-analysis aimed to evaluate the effectiveness of gamified interventions and their healthcare potential by testing the scalability and sustainability of their influence on physical activity (PA) and sedentary behaviors (SB). METHODS Five electronic databases (Pubmed, EMBASE, Scopus, Web of Science and CENTRAL) were searched for randomized controlled trials (RCTs) published since 2010. Eligibility criteria were based on components of PICO (participants, interventions, comparators, and outcomes). Studies were included when they used gamified interventions in daily life with an active or inactive control group, and when they assessed a PA or SB outcome. Studies were excluded when the intervention was based on an active video game using a gaming console. We conducted meta-analyses using a random effects model approach. Sensitivity analyses, influence analyses and publication bias analyses were performed to examine the robustness of our results. RESULTS The main meta-analysis performed on 16 studies and 2407 participants, revealed a small to medium summary effect of gamified interventions on PA behavior (g = 0.42 (95%CI [0.14, 0.69]). No statistical difference was found between different subgroups (adults vs adolescents, healthy participants vs adults with chronic diseases) and no interaction effects with moderators like age, gender or BMI, suggesting good scalability of gamified interventions. Moreover, the effect appears better on the step count (MD = +1609.56 steps per day (95%CI [372.39, 2846.73]) than on moderate-to-vigorous PA (g = 0.31 (95%CI [-0.19, 0.80]). The long-term effect (measured with follow-up averaging 14 weeks after the end of the intervention) is more volatile with a very small to small effect (g = 0.15, [0.07, 0.23]). CONCLUSIONS This meta-analysis confirms that gamified interventions are promising to promote PA in various publics. However, if the effect persists after the end of the program, suggesting that it is not just a novelty effect due to the playful nature of gamification, it seems volatile with a small long-term effect. The integration of gamification in more global healthcare interventions could be a way to address this low sustainability. Future rigorous trials are needed to explore these perspectives.

scholarly journals Long-Term Effect of Exercise on Irisin Blood Levels—Systematic Review and Meta-Analysis

Healthcare ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1438
Author(s):  
Tereza Jandova ◽  
Angel Buendía-Romero ◽  
Hana Polanska ◽  
Veronika Hola ◽  
Marcela Rihova ◽  
...  
Keyword(s):  
Systematic Review ◽  
Physical Exercise ◽  
Meta Analysis ◽  
Term Effect ◽  
Blood Levels ◽  
Biochemical Processes ◽  
Qualitative And Quantitative ◽  
Long Term Effect ◽  
Positive Effect

Physical exercise may activate a number of important biochemical processes in the human body. The aim of this systematic review and meta-analysis was to identify the long-term effect of physical activity on irisin blood levels. We searched PubMed, Scopus, and Web of Science for articles addressing the long-term effect of physical exercise on irisin blood levels. Fifty-nine articles were included in the final qualitative and quantitative syntheses. A statistically significant within-group effect of exercise on irisin blood levels was in 33 studies; out of them, the irisin level increased 23× and decreased 10×. The significant positive between-groups effect was found 11×. Furthermore, the meta-analysis indicated that physical exercise had a significant positive effect on irisin blood levels (SMD = 0.39 (95% CI 0.27–0.52)). Nevertheless, considerably high heterogeneity was found in all the analyses. This systematic review and meta-analysis indicate that physical exercise might increase irisin blood levels; however, the results of individual studies were considerably inconsistent, which questions the methodological detection of irisin by ELISA kits.

scholarly journals Long-Term Effect of Four Surgical Periodontal Therapies and One Non-Surgical Therapy: A Systematic Review and Meta-Analysis

2015 ◽  
Vol 86 (10) ◽  
pp. 1150-1158 ◽  
Author(s):  
James Mailoa ◽  
Guo-Hao Lin ◽  
Vahid Khoshkam ◽  
Mark MacEachern ◽  
Hsun-Liang Chan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Surgical Therapy ◽  
Meta Analysis ◽  
Term Effect ◽  
Long Term Effect

Long-Term Effect of Surface Roughness and Patients' Factors on Crestal Bone Loss at Dental Implants. A Systematic Review and Meta-Analysis

2016 ◽  
Vol 19 (2) ◽  
pp. 372-399 ◽  
Author(s):  
Ron Doornewaard ◽  
Véronique Christiaens ◽  
Hugo De Bruyn ◽  
Magnus Jacobsson ◽  
Jan Cosyn ◽  
...  
Keyword(s):  
Systematic Review ◽  
Surface Roughness ◽  
Bone Loss ◽  
Dental Implants ◽  
Meta Analysis ◽  
Term Effect ◽  
Crestal Bone Loss ◽  
Long Term Effect ◽  
Effect Of Surface

scholarly journals Long-term effect of non-surgical periodontal treatment on glycaemic control in patients with diabetes with periodontitis: a systematic review and meta-analysis protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e043250
Author(s):  
William Ndjidda Bakari ◽  
Ahmad Moustapha Diallo ◽  
Celestin Danwang ◽  
Rolf Nyah Tuku Nzalie ◽  
Henri Michel Benoist
Keyword(s):  
Systematic Review ◽  
Glycaemic Control ◽  
Meta Analysis ◽  
Random Effect ◽  
Term Effect ◽  
Periodontal Therapy ◽  
Final Report ◽  
Long Term Effect ◽  
Patients With Diabetes

IntroductionNon-surgical periodontal therapy consisting of scaling and root planning has been shown to be effective in the improvement of glycaemic control in patients with diabetes with periodontitis for up to 3 months. However, questions remain about this beneficial effect over a longer period of time. This systematic review and meta-analysis aims to determine the long-term effect (at least 6 months from the therapy) of non-surgical periodontal therapy with or without adjuvant on glycaemic control of patients with diabetes with periodontitis.Methods and analysisThis systematic review will include randomised control trials with a follow-up period of at least 6 months after initial therapy, with measurement of glycated haemoglobin as the primary endpoint. A literature search will be conducted in MEDLINE, CENTRAL, EMBASE, CINAHL, The Cochrane Oral Health Group Trials Register, and the US National Institutes of Health Trials Registry: ClinicalTrials.gov, from inception to 30 June 2020. Selection of studies, data extraction and bias assessment will be conducted independently by two reviewers. A DerSimonian-Laird random-effect meta-analysis will be conducted to pool studies deemed to be homogeneous. A subgroup analysis will be conducted in case of substantial heterogeneity. Egger’s test and observation of the funnel plot will be used to assess publication bias. The statistical analysis will be done using R V.4.0.0 software.Ethics and disseminationSince primary data are not collected, ethical approval is not required. The final report will be published in a peer-reviewed journal.PROSPERO registration numberCRD42020192635.

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