scholarly journals VP23.04: Maternal infection and adverse pregnancy outcomes among pregnant travellers: results of the international Zika virus in pregnancy registry

2020 ◽  
Vol 56 (S1) ◽  
pp. 156-156 ◽  
Author(s):  
M. Vouga ◽  
L. Pomar ◽  
A. Soriano‐Arandes ◽  
C. Rodo ◽  
A. Goncé ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Zika Virus ◽  
Adverse Pregnancy Outcomes ◽  
Maternal Infection ◽  
Adverse Pregnancy ◽  
Pregnancy Registry ◽  
In Pregnancy

scholarly journals Zika Virus Infection in a Cohort of Pregnant Women with Exanthematic Disease in Manaus, Brazilian Amazon

2020 ◽  
Author(s):  
Elijane de Fátima Redivo ◽  
Camila Helena Bôtto Menezes ◽  
Márcia da Costa Castilho ◽  
Marianna Facchinetti Brock ◽  
Evela da Silva Magno ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Pregnancy Outcomes ◽  
Zika Virus ◽  
Descriptive Analysis ◽  
First Trimester ◽  
Adverse Pregnancy Outcomes ◽  
Rt Pcr ◽  
Zikv Infection ◽  
Adverse Pregnancy ◽  
In Pregnancy

The epidemic transmission of Zika virus (ZIKV) in Brazil has been identified as a cause of microcephaly and other neurological malformations in babies of ZIKV-infected women. This study provides a descriptive analysis, since the onset of symptoms to the delivery, of a cohort who were registered as having ZIKV infection in pregnancy, from November 2015 to December 2016. Suspected cases were registered at a referral center for infectious and tropical diseases in Manaus, in the Brazilian Amazonian region. A total of 834 women with suspected ZIKV in pregnancy were included, of whom 91.4% had confirmed pregnancy. Reverse-transcriptase polymerase chain reaction (RT-PCR) confirmed ZIKV infection in 42.2% of the cohort. In 35.2% of the cohort, ZIKV was the sole infection identified. Severe adverse pregnancy outcomes (abortion, stillbirth, or microcephaly) were observed in both RT-PCR ZIKV-positive (4.96%) and ZIKV-negative (2.15%) cases. Women with suspected ZIKV infection were much more likely to have adverse pregnancy outcomes if they were symptomatic during the first trimester of pregnancy (odds ratio 10.5; 95% confidence interval 4.0–27.0; p<0.001). Among pregnant women with suspected ZIKV infection, the occurrence of symptoms in the first trimester is associated with an especially high risk of severe adverse pregnancy outcomes.

Comparison of pregnancy outcomes after second trimester amniocentesis between procedures performed by experts and non-experts

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Tanapak Wisetmongkolchai ◽  
Fuanglada Tongprasert ◽  
Kasemsri Srisupundit ◽  
Suchaya Luewan ◽  
Kuntharee Traisrisilp ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Loss Rate ◽  
Fetal Loss ◽  
Adverse Pregnancy Outcomes ◽  
Expert Group ◽  
Second Trimester ◽  
Single Institution ◽  
Adverse Pregnancy ◽  
In Pregnancy ◽  
Singleton Pregnancies

AbstractObjectivesTo compare the rate of fetal loss in pregnancy after second trimester amniocentesis between procedures performed by experts and non-experts and to assess other pregnancy complications as secondary outcomes.MethodsA retrospective cohort study was performed on singleton pregnancies that underwent mid-trimester amniocenteses in a single institution. The fetal loss rates of procedures performed by experts and non-experts were collected and analyzed. Other adverse pregnancy outcomes were also examined.ResultsIn total, 14,450 amniocenteses were performed during the study period. These included 11,357 (78.6%) procedures in the group expert operators and 3,093 (21.4%) procedures in the group non-expert operators. In the non-expert group, the fetal loss rate was slightly increased but not significantly (p=0.24).In addition, the higher number of spontaneous abortions was associated with blood-stained amniotic fluid sample (p<0.001; RR=9.28). Multiple needle insertions also increased in the non-expert group significantly. However, no difference in pregnancy outcomes was found between in single and multiple needle insertions.ConclusionsThe amniocentesis procedures performed by the non-experts was not increase the fetal loss rate. However, the other adverse pregnancy outcomes, including preterm birth, low birth weight and fetal growth restriction were significantly increased in the non-expert group.

scholarly journals Maternal Infection and Adverse Pregnancy Outcomes among Pregnant Travellers: Results of the International Zika Virus in Pregnancy Registry

Viruses ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 341
Author(s):  
Manon Vouga ◽  
Léo Pomar ◽  
Antoni Soriano-Arandes ◽  
Carlota Rodó ◽  
Anna Goncé ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Adverse Pregnancy Outcomes ◽  
Minimal Risk ◽  
Maternal Infection ◽  
Caribbean Islands ◽  
Multicentre Cohort Study ◽  
Epidemic Period ◽  
The Caribbean ◽  
Adverse Pregnancy ◽  
Multicentre Cohort

In this multicentre cohort study, we evaluated the risks of maternal ZIKV infections and adverse pregnancy outcomes among exposed travellers compared to women living in areas with ZIKV circulation (residents). The risk of maternal infection was lower among travellers compared to residents: 25.0% (n = 36/144) versus 42.9% (n = 309/721); aRR 0.6; 95% CI 0.5–0.8. Risk factors associated with maternal infection among travellers were travelling during the epidemic period (i.e., June 2015 to December 2016) (aOR 29.4; 95% CI 3.7–228.1), travelling to the Caribbean Islands (aOR 3.2; 95% CI 1.2–8.7) and stay duration >2 weeks (aOR 8.7; 95% CI 1.1–71.5). Adverse pregnancy outcomes were observed in 8.3% (n = 3/36) of infected travellers and 12.7% (n = 39/309) of infected residents. Overall, the risk of maternal infections is lower among travellers compared to residents and related to the presence of ongoing outbreaks and stay duration, with stays <2 weeks associated with minimal risk in the absence of ongoing outbreaks.

scholarly journals Schistosomiasis among pregnant women in the Njombe-Penja health district, Littoral region of Cameroon: A cross sectional study

2019 ◽  
Author(s):  
Calvin Tonga ◽  
Charlie Ngo Bayoi ◽  
Flore Chanceline Tchanga ◽  
Jacqueline Félicité Yengue ◽  
Godlove Bunda Wepnje ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Pregnancy Outcomes ◽  
Haemoglobin Concentration ◽  
Epidemiological Data ◽  
Adverse Pregnancy Outcomes ◽  
Health District ◽  
Blood Levels ◽  
Childbearing Age ◽  
Adverse Pregnancy ◽  
In Pregnancy

AbstractBackgroundSchistosomiasis is a Neglected Tropical Disease with endemic foci in Cameroon. Epidemiological data on schistosomiasis in pregnancy are scarce in the country. This study is about schistosomiasis among pregnant women in the Njombe-Penja health district, where schistosomiasis was reported since 1969.MethodologyOverall, 282 pregnant women were enrolled upon informed consent at first antenatal consultation. A questionnaire was administered to document socio-economic and obstetric information. Stool and terminal urine samples were collected and analysed using the Kato-Katz/formol-ether concentration techniques and centrifugation method respectively. Haemoglobin concentration was measured with finger prick blood, using a URIT-12® electronic haemoglobinometer.Principal findingsThe overall prevalence of schistosomiasis was 31.91%. Schistosoma guineensis, S. haematobium and S. mansoni infections were found in 0.35%, 04.96% and 28.01% of participants respectively. Co-infection with 2 species of Schistosoma was found in 04.44% of these women. The prevalence of schistosomiasis was significantly higher in younger women (≤20) and among residents of Njombe. All S. haematobium infected women were anemic and infection was associated with significantly lower haemoglobin levels (p=0.02).ConclusionThe prevalence of schistosomiasis is high in pregnant women of the Njombe-Penja health district, with possible adverse pregnancy outcomes. Female of childbearing age should be considered for mass drug administration.Author summaryPregnant women are known to be more vulnerable to infectious diseases and in their case, at least two lives are at risk. Although schistosomiasis remains a major public health issue in Cameroon, epidemiological data on schistosomiasis in pregnancy are scarce. These data are of high interest for informed decision-making. We examined stools and urines from 282 women of the Njombe-Penja Health district and measured their blood levels. Overall, 31.91% of women were infected, mostly younger ones and those living in the town of Njombe. Three species of Schistosoma parasite were identified. Women having urinary schistosomiasis had lower blood levels. These results show that the prevalence of schistosomiasis is high in pregnant women of Njombe. Also, because of the anemia it induces, the disease can lead to adverse pregnancy outcomes on the woman and her foetus. Treating female of childbearing age would cure the disease and prevent adverse outcomes.

scholarly journals 142: Migraines in pregnancy and select adverse pregnancy outcomes

2020 ◽  
Vol 222 (1) ◽  
pp. S106
Author(s):  
Gretchen Bandoli ◽  
Rebecca J. Baer ◽  
Laura L. Jelliffe-Pawlowski ◽  
Christina Chambers
Keyword(s):  
Pregnancy Outcomes ◽  
Adverse Pregnancy Outcomes ◽  
Adverse Pregnancy ◽  
In Pregnancy

Abstract MP096: Patterns of Physical Activity Across Pregnancy and Their Association With Adverse Pregnancy Outcomes

Circulation ◽  
2017 ◽  
Vol 135 (suppl_1) ◽  
Author(s):  
Janet M Catov ◽  
Corette B Parker ◽  
Bethany B Gibbs ◽  
Carla Bann ◽  
Benjamin Carper ◽  
...  
Keyword(s):  
Physical Activity ◽  
Pregnancy Outcomes ◽  
Activity Patterns ◽  
Growth Mixture Modeling ◽  
Adverse Pregnancy Outcomes ◽  
Metabolic Equivalents ◽  
Nulliparous Women ◽  
Adverse Pregnancy ◽  
Low Activity ◽  
In Pregnancy

Background: Cardiovascular disease (CVD) is the leading cause of death among women, and pregnancy complications reveal risk decades before overt CVD. While physical activity is related to CVD, less is known about how the activity patterns during pregnancy may contribute to adverse pregnancy outcomes. Hypothesis: Increasing activity across pregnancy is related to reduced risk of adverse pregnancy outcomes. Methods: Nulliparous women were enrolled at 8 centers early in pregnancy (n=10,020). Frequency and duration of up to three leisure activities reported in the first, second and third trimester were analyzed as metabolic equivalents (METs). Growth mixture modeling was used to identify activity patterns in pregnancy. Adverse outcomes (preterm birth [PTB], hypertensive disease of pregnancy [HDP], and gestational diabetes [GDM]) were collected by chart abstraction. Results: Four patterns of activity across pregnancy were identified: sustained high (3%, n=297); increasing (12%, n=1231); sustained low (77%, n=7717); and decreasing (8%, n=775; Figure). Women with sustained low activity were younger and more likely to be black or Hispanic, obese, or to have smoked prior to pregnancy when compared to those with increasing activity. Women with sustained low vs. increasing activity had higher rates of PTB (9.2 vs. 6.2%), HDP (13.8 vs. 10.5%), and GDM (4.7 vs. 2.5%; all p <0.01). After adjusting for maternal factors (age, race/ethnicity, BMI and smoking), the risk of GDM remained higher in women with sustained low activity compared with those having increasing activity patterns (adjusted OR 1.79 [1.21, 2.66]). Sustained low activity was also associated with higher risk of PTB (adjusted OR 1.36 [1.05, 1.76]). Conclusion: The majority of women have sustained low activity across pregnancy, and this is independently associated with higher risks of GDM and PTB. These associations raise the possibility that increased activity during pregnancy may improve pregnancy outcomes, and perhaps long-term maternal cardiovascular health.

Low maternal weight, failure to thrive in pregnancy, and adverse pregnancy outcomes

2003 ◽  
Vol 189 (6) ◽  
pp. 1726-1730 ◽  
Author(s):  
Hugh M Ehrenberg ◽  
LeRoy Dierker ◽  
Cynthia Milluzzi ◽  
Brian M Mercer
Keyword(s):  
Pregnancy Outcomes ◽  
Failure To Thrive ◽  
Adverse Pregnancy Outcomes ◽  
Maternal Weight ◽  
Adverse Pregnancy ◽  
In Pregnancy
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