scholarly journals VP15.06: Peripheral chemoreflex and cardiac function during acute hypoxemia and metabolic acidosis without placental compromise in late‐term sheep fetuses

2020 ◽  
Vol 56 (S1) ◽  
pp. 113-114
Author(s):  
J. Lantto ◽  
H. Huhta ◽  
L. Alanne ◽  
M. Haapsamo ◽  
A. Bhide ◽  
...  
Keyword(s):  
Metabolic Acidosis ◽  
Cardiac Function ◽  
Peripheral Chemoreflex

Metabolic Acidosis

2016 ◽  
Author(s):  
Steve Krywawych
Keyword(s):  
Metabolic Acidosis ◽  
Cardiac Function ◽  
Hydrogen Concentration ◽  
Metabolic Diseases ◽  
Hydrogen Ion ◽  
Variable Degree ◽  
Ion Balance ◽  
Essential Requirement ◽  
Underlying Causes ◽  
Per Se

Hydrogen ion turnover in resting adults exceeds 500 mole/24 hours and maintenance of hydrogen ion balance is an essential requirement for normal cellular, organ and body function. A variety of mechanisms co-operate to ensure that the hydrogen concentration in plasma can be tightly controlled between 35 to 46 nano moles per litre and any deviation being rapidly compensated. Inherited metabolic diseases can to a variable degree impact to disturb this equilibrium. The underlying causes responsible for this outcome are disease dependent and may occur due to generation of overwhelming quantities of hydrogen per se, or at the level of renal reabsorption or generation of bicarbonate or due to tissue hypoxia resulting from either poor pulmonary or cardiac function.

Exercise training attenuates the pressor response evoked by peripheral chemoreflex in rats with heart failure

2016 ◽  
Vol 94 (9) ◽  
pp. 979-986 ◽  
Author(s):  
Leonardo Calegari ◽  
Bruna B. Mozzaquattro ◽  
Douglas D. Rossato ◽  
Edson Quagliotto ◽  
Janaina B. Ferreira ◽  
...  
Keyword(s):  
Heart Failure ◽  
Exercise Training ◽  
Cardiac Function ◽  
Diastolic Pressure ◽  
Pressor Response ◽  
Potassium Cyanide ◽  
Left Ventricular ◽  
Treadmill Running ◽  
Chemoreflex Sensitivity ◽  
Peripheral Chemoreflex

The effects of exercise training (ExT) on the pressor response elicited by potassium cyanide (KCN) in the rat model of ischemia-induced heart failure (HF) are unknown. We evaluated the effects of ExT on chemoreflex sensitivity and its interaction with baroreflex in rats with HF. Wistar rats were divided into four groups: trained HF (Tr-HF), sedentary HF (Sed-HF), trained sham (Tr-Sham), and sedentary sham (Sed-Sham). Trained animals underwent to a treadmill running protocol for 8 weeks (60 m/day, 5 days/week, 16 m/min). After ExT, arterial pressure (AP), baroreflex sensitivity (BRS), peripheral chemoreflex (KCN: 100 μg/kg body mass), and cardiac function were evaluated. The results demonstrate that ExT induces an improvement in BRS and attenuates the pressor response to KCN relative to the Sed-HF group (P < 0.05). The improvement in BRS was associated with a reduction in the pressor response following ExT in HF rats (P < 0.05). Moreover, ExT induced a reduction in left ventricular end-diastolic pressure and pulmonary congestion compared with the Sed-HF group (P < 0.05). The pressor response to KCN in the hypotensive state is decreased in sedentary HF rats. These results suggest that ExT improves cardiac function and BRS and attenuates the pressor response evoked by KCN in HF rats.

551 Bromocriptine prevents deterioration of cardiac function in patients with PPCM after subsequent pregnancy

2006 ◽  
Vol 5 (1) ◽  
pp. 122-123
Author(s):  
O FORSTER ◽  
D HILFIKERKLEINER ◽  
A YIP ◽  
A BECKER ◽  
M NEL ◽  
...  
Keyword(s):  
Cardiac Function ◽  
Subsequent Pregnancy

Reduction of HMG-CoA-reductase leads to improved cardiac function in doxorubicin-induced cardiomyopathy in mice

2008 ◽  
Vol 7 ◽  
pp. 202-203
Author(s):  
A RIAD ◽  
S BIEN ◽  
F ESCHER ◽  
D WESTERMANN ◽  
U LANDMESSER ◽  
...  
Keyword(s):  
Cardiac Function ◽  
Hmg Coa Reductase ◽  
Coa Reductase

Cardiac function in idiopathic edema

1974 ◽  
Vol 134 (2) ◽  
pp. 253-258 ◽  
Author(s):  
A. I. Obeid
Keyword(s):  
Cardiac Function ◽  
Idiopathic Edema
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