scholarly journals Outcome of monochorionic twin pregnancy with selective fetal growth restriction at 16, 20 or 30 weeks according to new Delphi consensus definition

2020 ◽  
Vol 56 (6) ◽  
pp. 821-830 ◽  
Author(s):  
I. Couck ◽  
S. Ponnet ◽  
J. Deprest ◽  
R. Devlieger ◽  
L. De Catte ◽  
...  
Keyword(s):  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Twin Pregnancy ◽  
Growth Restriction ◽  
Delphi Consensus ◽  
Consensus Definition ◽  
Monochorionic Twin

Possible molecular and biological mechanisms for the development of selective fetal growth restriction in monochorionic twin pregnancy

2021 ◽  
Vol 10_2021 ◽  
pp. 5-12
Author(s):  
Neftereva A.A. Neftereva ◽  
Sakalo V.A. Sakalo ◽  
Gladkova K.A. Gladkova ◽  
Kоstyukov K.V. Kоstyukov K ◽  
Khodzhaeva Z.S. Khodzhaeva ◽  
...  
Keyword(s):  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Twin Pregnancy ◽  
Growth Restriction ◽  
Biological Mechanisms ◽  
Monochorionic Twin

scholarly journals Consensus Definition of Fetal Growth Restriction in Intrauterine Fetal Death: A Delphi Procedure

2020 ◽  
Author(s):  
Irene Maria Beune ◽  
Stefanie Elisabeth Damhuis ◽  
Wessel Ganzevoort ◽  
John Ciaran Hutchinson ◽  
Teck Yee Khong ◽  
...  
Keyword(s):  
Birth Weight ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Fetal Death ◽  
Weight Ratio ◽  
Liver Weight ◽  
Growth Restriction ◽  
Intrauterine Fetal Death ◽  
Consensus Definition ◽  
Definition Of

Context.— Fetal growth restriction is a risk factor for intrauterine fetal death. Currently, definitions of fetal growth restriction in stillborn are heterogeneous. Objectives.— To develop a consensus definition for fetal growth restriction retrospectively diagnosed at fetal autopsy in intrauterine fetal death. Design.— A modified online Delphi survey in an international panel of experts in perinatal pathology, with feedback at group level and exclusion of nonresponders. The survey scoped all possible variables with an open question. Variables suggested by 2 or more experts were scored on a 5-point Likert scale. In subsequent rounds, inclusion of variables and thresholds were determined with a 70% level of agreement. In the final rounds, participants selected the consensus algorithm. Results.— Fifty-two experts participated in the first round; 88% (46 of 52) completed all rounds. The consensus definition included antenatal clinical diagnosis of fetal growth restriction OR a birth weight lower than third percentile OR at least 5 of 10 contributory variables (risk factors in the clinical antenatal history: birth weight lower than 10th percentile, body weight at time of autopsy lower than 10th percentile, brain weight lower than 10th percentile, foot length lower than 10th percentile, liver weight lower than 10th percentile, placental weight lower than 10th percentile, brain weight to liver weight ratio higher than 4, placental weight to birth weight ratio higher than 90th percentile, histologic or gross features of placental insufficiency/malperfusion). There was no consensus on some aspects, including how to correct for interval between fetal death and delivery. Conclusions.— A consensus-based definition of fetal growth restriction in fetal death was determined with utility to improve management and outcomes of subsequent pregnancies.

Whole genome miRNA profiling revealed miR-199a as potential placental pathogenesis of selective fetal growth restriction in monochorionic twin pregnancies

Placenta ◽  
2020 ◽  
Vol 92 ◽  
pp. 44-53 ◽  
Author(s):  
Meng Meng ◽  
Yvonne Kwun Yue Cheng ◽  
Ling Wu ◽  
Piya Chaemsaithong ◽  
Maran Bo Wah Leung ◽  
...  
Keyword(s):  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Growth Restriction ◽  
Whole Genome ◽  
Monochorionic Twin ◽  
Mirna Profiling ◽  
Twin Pregnancies
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