Large‐for‐gestational age diagnosed during second‐trimester anatomy ultrasound and association with gestational diabetes and large‐for‐gestational age at birth

2020 ◽  
Vol 56 (6) ◽  
pp. 901-905 ◽  
Author(s):  
P. Rekawek ◽  
L. Liu ◽  
C. Getrajdman ◽  
C. Brooks ◽  
S. Pan ◽  
...  
Keyword(s):  
Gestational Diabetes ◽  
Gestational Age ◽  
Large For Gestational Age ◽  
Second Trimester ◽  
Gestational Age At Birth ◽  
Age At Birth

scholarly journals Uterine distention as a factor in birth timing: retrospective nationwide cohort study in Sweden

BMJ Open ◽  
2018 ◽  
Vol 8 (10) ◽  
pp. e022929 ◽  
Author(s):  
Jonas Bacelis ◽  
Julius Juodakis ◽  
Kristina M Adams Waldorf ◽  
Verena Sengpiel ◽  
Louis J Muglia ◽  
...  
Keyword(s):  
Cohort Study ◽  
Preterm Birth ◽  
Fetal Growth ◽  
Gestational Age ◽  
Large For Gestational Age ◽  
Maternal Height ◽  
Birth Timing ◽  
Gestational Age At Birth ◽  
Age At Birth ◽  
Singleton Pregnancies

ObjectivesTo determine whether uterine distention is associated with human pregnancy duration in a non-invasive observational setting.DesignRetrospective cohort study modelling uterine distention by interaction between maternal height and uterine load.SettingThe study is based on the 1990–2013 population data from all delivery units in Sweden.ParticipantsUncomplicated first pregnancies of healthy Nordic-born mothers with spontaneous onset of labour. Pregnancies were classified as twin (n=2846) or singleton (n=527 868). Singleton pregnancies were further classified as carrying a large for gestational age fetus (LGA, n=24 286) or small for gestational age fetus (SGA, n=33 780).Outcome measuresStatistical interaction between maternal height and uterine load categories (twin vs singleton pregnancies, and LGA vs SGA singleton pregnancies), where the outcome is pregnancy duration.ResultsIn all models, statistically significant interaction was found. Mothers carrying twins had 2.9 times larger positive linear effect of maternal height on gestational age than mothers carrying singletons (interaction p=5e−14). Similarly, the effect of maternal height was strongly modulated by the fetal growth rate in singleton pregnancies: the effect size of maternal height on gestational age in LGA pregnancies was 2.1 times larger than that in SGA pregnancies (interaction p<1e−11). Preterm birth OR was 1.4 when the mother was short, and 2.8 when the fetus was extremely large for its gestational age; however, when both risk factors were present together, the OR for preterm birth was larger than expected, 10.2 (interaction p<0.0005).ConclusionsAcross all classes, maternal height was significantly associated with child’s gestational age at birth. Interestingly, in short-statured women with large uterine load (twins, LGA), spontaneous delivery occurred much earlier than expected. The interaction between maternal height, uterine load size and gestational age at birth strongly suggests the effect of uterine distention imposed by fetal growth on birth timing.

Fetal abdominal circumference in the second trimester and prediction of small for gestational age at birth

2019 ◽  
Vol 33 (14) ◽  
pp. 2415-2421
Author(s):  
Georgios Doulaveris ◽  
Patience Gallagher ◽  
Elizabeth Romney ◽  
Michael Richley ◽  
Juliana Gebb ◽  
...  
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Abdominal Circumference ◽  
Second Trimester ◽  
Gestational Age At Birth ◽  
Age At Birth

OP01.02: Enlarged nuchal translucency: more common in boys large for gestational age at birth

2008 ◽  
Vol 32 (3) ◽  
pp. 308-308
Author(s):  
E. Timmerman ◽  
E. Pajkrt ◽  
M. C. van Maarle ◽  
R. J. M. Snijders ◽  
C. M. Bilardo
Keyword(s):  
Gestational Age ◽  
Nuchal Translucency ◽  
Large For Gestational Age ◽  
Gestational Age At Birth ◽  
Age At Birth

scholarly journals The role of three-dimensional ultrasound in pregnancies submitted to cerclage

2018 ◽  
Vol 64 (7) ◽  
pp. 620-626
Author(s):  
Thais da Fonseca Borghi ◽  
Mário Henrique Burlacchini de Carvalho ◽  
Antonio Gomes de Amorim Filho ◽  
Silvio Martinelli ◽  
Marcelo Zugaib ◽  
...  
Keyword(s):  
Gestational Age ◽  
Cox Regression ◽  
Three Dimensional ◽  
Cervical Length ◽  
Second Trimester ◽  
Regression Analyses ◽  
Third Trimester ◽  
The Third ◽  
Gestational Age At Birth ◽  
Age At Birth

SUMMARY OBJECTIVE: Cervical cerclage is the standard treatment for cervical incompetence (CI); however, there is still a high risk of preterm birth for women who undergo this treatment. The aim of this study was to longitudinally evaluate findings on two-dimensional transvaginal ultrasonography (2DTVUS) and three-dimensional transvaginal ultrasonography (3DTVUS) that could be related to gestational age at birth. METHODS: A total of 68 pregnant women who were treated with cerclage were evaluated by 2DTVUS and 3DTVUS in the second and third trimesters of pregnancy. Log-rank tests and Cox regression analyses were used to identify significant findings related to gestational age at delivery. RESULTS: A cervical length lower than 281 mm (p= 0.0083), a proximal cervical length lower than 10 mm (p= 0.0151), a cervical volume lower than 18.17 cm3 (p= 0.0152), a vascularization index (VI) under 2.153 (p= 0.0044), and a vascularization-flow index (VFI) under 0.961 (p= 0.0059) in the second trimester were all related to earlier delivery. In the third trimester, a cervical length lower than 20.4 mm (p= 0.0009), a VI over 0.54 (p= 0.0327) and a VFI over 2.275 (p= 0.0479) were all related to earlier delivery. Cervical funnelling in the second and third trimesters and proximal cervical length in the third trimester were not related to gestational age at birth. The COX regression analyses showed that cervical volume in the second trimester; FI and VFI in the third trimester were significantly associated with gestational age at birth. CONCLUSION: In women treated with history-indicated cerclage or ultrasound-indicated cerclage, 2nd trimester cervical volume and 3rd trimester FI and VFI are independent significant sonographic findings associated with time to delivery.

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