scholarly journals OC29.02: Prevalence of an aberrant right subclavian artery (ARSA) in normal fetuses: a new soft marker for trisomy 21 risk assessment

2005 ◽  
Vol 26 (4) ◽  
pp. 356-356 ◽  
Author(s):  
R. Chaoui ◽  
G. Thiel ◽  
K. S. Heling
Keyword(s):  
Risk Assessment ◽  
Subclavian Artery ◽  
Trisomy 21 ◽  
Aberrant Right Subclavian Artery ◽  
Soft Marker

scholarly journals Aberrant right subclavian artery as soft marker in the diagnosis of trisomy 21 during the first trimester of pregnancy

2021 ◽  
Author(s):  
Cristina Martínez-Payo ◽  
Elena Suanzes ◽  
Ana Gómez-Manrique ◽  
Alexandra Arranz ◽  
Tirso Pérez-Medina
Keyword(s):  
Subclavian Artery ◽  
Predictive Value ◽  
Trisomy 21 ◽  
Anatomical Variation ◽  
First Trimester ◽  
Aberrant Right Subclavian Artery ◽  
Cross Sectional ◽  
First Trimester Of Pregnancy ◽  
Soft Marker ◽  
First Trimester Ultrasound

Abstract Purpose Aberrant right subclavian artery is an anatomical variation with a prevalence of around 0.5–1.5% of the general population, being more frequently found among people with chromosomopathies, especially, trisomy 21. Despite being an anatomical finding, and thus, constant through the whole pregnancy, its value in the diagnosis of aneuploidies during the first trimester of pregnancy has been little studied. The aim of this study is to evaluate the reliability of the first-trimester ultrasound in the diagnosis of ARSA and its utility in the early diagnosis of aneuploidies. Methods This was a descriptive, observational, cross-sectional study that included all fetuses with sonographic diagnosis of ARSA between 2011 and 2018. Results There were 257 cases of ARSA diagnosed. The first-trimester ultrasound showed the following results in the detection of ARSA: sensitivity of 68% (CI 95% 60.8%–74.5%), specificity of 99.9% (CI 95% 99.9%–100%), positive predictive value of 93.7% (CI 95% 88.1%–96.8%), and negative predictive value of 99.6% (CI 95% 99.5%–99.7%). Due to the presence of ARSA, two cases of trisomy 21, that would have been missed in the first trimester, were diagnosed, using ARSA as a soft marker and modifying the risk obtained by the combined screening as part of the genetic sonogram of the first trimester. Conclusions ARSA visualization during the first-trimester ultrasound is trustworthy and it can improve the detection of trisomy 21 in some cases of aneuploidy missed during the combined screening of the first trimester.

P01.01: Aberrant right subclavian artery (ARSA) in fetuses with trisomy 21

2009 ◽  
Vol 34 (S1) ◽  
pp. 177-177 ◽  
Author(s):  
R. Chaoui ◽  
A. Sarut Lopez ◽  
A. Bergann ◽  
K. S. Heling
Keyword(s):  
Subclavian Artery ◽  
Trisomy 21 ◽  
Aberrant Right Subclavian Artery

scholarly journals Anatomic Investigation of Two Cases of Aberrant Right Subclavian Artery Syndrome, Including the Effects on External Vascular Dimensions

Diagnostics ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 592
Author(s):  
Mitchell H. Mirande ◽  
Madelyn R. Durhman ◽  
Heather F. Smith
Keyword(s):  
Risk Assessment ◽  
Aortic Arch ◽  
Subclavian Artery ◽  
Relative Size ◽  
Aberrant Right Subclavian Artery ◽  
Normal Sample ◽  
Surgical Interventions ◽  
Brachiocephalic Trunk ◽  
The Right

The retroesophageal aberrant right subclavian artery (ARSA) is a variation of the aortic arch that occurs asymptomatically in most patients. However, when symptomatic, it is most commonly associated with dysphagia. ARSA has also been noted as a location of potentially severe aneurysms in some patients, as well as posing a risk during surgical interventions in the esophageal region. This case study analyzes two individuals with ARSA morphology in comparison to a normal sample in order to gain a better anatomical understanding of this anomaly, potentially leading to better risk assessment of ARSA patients going forward. The diameter of the ARSA vessel was found to be substantially larger than both the right subclavian artery and brachiocephalic trunk of the subjects with classic aortic arch anatomy. As many ARSA individuals are asymptomatic, we hypothesize that the relative size of the ARSA may dictate its contribution to the presence and/or severity of associated symptomatology.

OP15.03: Isolated aberrant right subclavian artery in low risk population: is it really a Trisomy 21 marker?

2014 ◽  
Vol 44 (S1) ◽  
pp. 97-98
Author(s):  
A. Fervienza ◽  
M. Bennasar ◽  
O. Gómez ◽  
F. Crispi ◽  
N. Masoller ◽  
...  
Keyword(s):  
Subclavian Artery ◽  
Trisomy 21 ◽  
Low Risk ◽  
Aberrant Right Subclavian Artery ◽  
Risk Population

scholarly journals P25.02: Isolated aberrant right subclavian artery: a marker of trisomy 21

2012 ◽  
Vol 40 (S1) ◽  
pp. 263-264
Author(s):  
E. Gomez Montes ◽  
I. Herraiz ◽  
J. M. Martinez-Moratalla Valcarcel ◽  
A. Galindo
Keyword(s):  
Subclavian Artery ◽  
Trisomy 21 ◽  
Aberrant Right Subclavian Artery

It's time to include the assessment of the aberrant right subclavian artery as screening test on ultrasound examination at 18–21 weeks of gestation

2018 ◽  
Author(s):  
M.V. Medvedev, A.Yu. Blinov, N.A. Altynnik et all
Keyword(s):  
Risk Factors ◽  
Subclavian Artery ◽  
Gestational Age ◽  
Trisomy 21 ◽  
Chromosomal Abnormalities ◽  
Ultrasound Examination ◽  
Genetic Diagnosis ◽  
Invasive Procedure ◽  
Aberrant Right Subclavian Artery ◽  
Increased Risk

Aberrant right subclavian artery (ARSA) is the most common embryologic abnormality of the aortic arch. 3973 fetuses were examined by ultrasound at 12–34 weeks of gestation and 34 fetuses with ARSA (mean gestational age: 20.2 weeks) was identified in our centre. ARSA was assessed in the axial plane on the level of three vessels and trachea view. ARSA was an isolated finding in 19 (55.9%) fetuses and non-isolated in 15 (44.1 %) fetuses. 6 (17.6 %) of these of 34 were aneuploidies: Trisomy 21 was diagnosed in 5 fetuses, Trisomy 18 in 1 fetus. 22q11 microdeletion was detected in 1 fetus. No cases with chromosomal abnormalities were detected in all 19 fetuses with isolated ARSA. Isolated ARSA does not seem to be associated with a significantly increased risk of aneuploidy. When ARSA is identified a detailed anatomy scan should be recommended. An invasive procedure with genetic diagnosis should be discussed when additional ultrasound abnormalities or risk factors for aneuploidy are found. Prenatal ultrasound diagnosis of ARSA based on previously published cases are discussed.

Detection Rate of Trisomy 21 in Fetuses with Isolated and Non-Isolated Aberrant Right Subclavian Artery

2013 ◽  
Vol 34 (3) ◽  
pp. 140-145 ◽  
Author(s):  
Aytul Corbacioglu Esmer ◽  
Ahmet Gul ◽  
Aslı Nehir ◽  
Atil Yuksel ◽  
Ozlem Dural ◽  
...  
Keyword(s):  
Subclavian Artery ◽  
Trisomy 21 ◽  
Detection Rate ◽  
Aberrant Right Subclavian Artery

Fetal Aberrant Right Subclavian Artery (ARSA) – a Potential New Soft Marker in the Genetic Scan?

2011 ◽  
Vol 33 (07) ◽  
pp. E114-E118 ◽  
Author(s):  
A. Willruth ◽  
N. Dwinger ◽  
J. Ritgen ◽  
R. Stressig ◽  
A. Geipel ◽  
...  
Keyword(s):  
Subclavian Artery ◽  
Aberrant Right Subclavian Artery ◽  
Soft Marker

scholarly journals The associtation between aberrant right subclavian artery and trisomy 21 in a tertiary center in Turkey

2020 ◽  
Vol 91 (8) ◽  
pp. 460-464
Author(s):  
Mete Sucu ◽  
Mehmet Özsürmeli ◽  
Erol Arslan ◽  
Cansun Demir ◽  
Cüneyt Evrüke
Keyword(s):  
Subclavian Artery ◽  
Trisomy 21 ◽  
Aberrant Right Subclavian Artery ◽  
Tertiary Center
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