scholarly journals OP16.08: Prediction of small for gestational age: added contribution of second to third trimester growth velocity

2019 ◽  
Vol 54 (S1) ◽  
pp. 139-140
Author(s):  
R.J. Martinez‐Portilla ◽  
M. Giannone ◽  
M. Rial‐Crestelo ◽  
A. Cancemi ◽  
F. Figueras
PEDIATRICS ◽  
1976 ◽  
Vol 57 (3) ◽  
pp. 363-371
Author(s):  
Eleanor Colle ◽  
David Schiff ◽  
Gail Andrew ◽  
Charles B. Bauer ◽  
Pamela Fitzhardinge

Growth characteristics of 15 full-term infants, selected because of weights more than 2 SD below the mean for gestational age, are described. The response to an intravenous injection of glucose was utilized to measure the insulin response of the infants at 6 months. Infants small for gestational age grow at a faster rate than appropriate-for-age infants during the first six months of life. There was a positive correlation between the growth velocity of the period and insulin release and a negative correlation between growth velocity and birth length. There was no correlation between these variables and increases in weight during the same period. Growth velocity during catch-up growth is related to the degree of preceding retardation but insulin may play a permissive role.


2007 ◽  
Vol 92 (7) ◽  
pp. 2758-2763 ◽  
Author(s):  
Rikke Beck Jensen ◽  
Signe Vielwerth ◽  
Torben Larsen ◽  
Gorm Greisen ◽  
Henrik Leffers ◽  
...  

Abstract Context: A common polymorphism in the GH receptor (GHR) gene has been linked to increased growth response in GH-treated patients. No former study has focused on the association to prenatal growth. Objective: The aim of the study was to evaluate the association between the d3-GHR isoforms and spontaneous pre- and postnatal growth. Design: A prospective study was conducted on third-trimester fetal growth velocity (FGV), birth weight, birth length, and postnatal growth. Setting: The study was conducted at Copenhagen University Hospital. Participants: A total of 115 healthy adolescents were divided into those born small for gestational age (SGA) and appropriate for gestational age with or without intrauterine growth restriction. Main Outcome Measures: FGV was measured by serial ultrasonography, birth weight, birth length, and adolescent height. Isoforms of the d3-GHR gene (fl/fl, d3/fl, and d3/d3) were determined. Results: The prevalence of the d3-GHR isoforms was 50% but differed among the groups (P = 0.006), with a high prevalence (88%) in the group born SGA with verified intrauterine growth restriction. The d3-GRH allele were associated with decreased third-trimester FGV (P = 0.05) in SGA subjects. In the entire cohort, carriers of the d3-GHR allele had a significantly increased height (−0.10 vs. 0.34 sd score; P = 0.017) and change in height from birth to adolescence compared with carriers of the full-length GHR allele (0.57 vs. −0.02 sd score; P = 0.005). Conclusions: This study showed an increased spontaneous postnatal growth velocity in the carriers of the d3-GHR allele. Interestingly, we found the opposite effect on prenatal growth in the SGA group, with a decreased FGV in carriers of the d3-GHR allele.


2019 ◽  
Vol 54 (S1) ◽  
pp. 357-358
Author(s):  
N. Dominguez ◽  
B. Gómez Alonso ◽  
A. Betegón Putze ◽  
P. Beira Salvador ◽  
C. Montes Prieto

2019 ◽  
Vol 54 (S1) ◽  
pp. 48-48
Author(s):  
G. Albaiges ◽  
M. Echevarria ◽  
N. Caner ◽  
L. Perdomo ◽  
I. Rodríguez ◽  
...  

2019 ◽  
Vol 33 (20) ◽  
pp. 3484-3489
Author(s):  
Sarah G. Običan ◽  
Linda Odibo ◽  
Methodius G. Tuuli ◽  
Alejandro Rodriguez ◽  
Anthony O. Odibo

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