scholarly journals OP12.08: Role of progesterone, cerclage and pessary in preventing preterm birth in twin pregnancies: a systematic review and network meta‐analysis

2019 ◽  
Vol 54 (S1) ◽  
pp. 125-126
Author(s):  
F. D'Antonio ◽  
V. Berghella ◽  
A. Odibo ◽  
G. Saccone ◽  
F. Sileo ◽  
...  
Author(s):  
Francesco D’Antonio ◽  
Vincenzo Berghella ◽  
Daniele Di Mascio ◽  
Gabriele Saccone ◽  
Filomena Sileo ◽  
...  

2021 ◽  
pp. 1-7
Author(s):  
Kamran Hessami ◽  
Maryam Kasraeian ◽  
Álvaro Sepúlveda-Martínez ◽  
Mauro Cristian Parra-Cordero ◽  
Homeira Vafaei ◽  
...  

The alteration of the uterocervical angle (UCA) has been proposed to play an important role in spontaneous preterm birth (sPTB). The aim of this systematic review and meta-analysis was to evaluate the evidence on the UCA predictive role in sPTB. In this study, PubMed, Web of Science, Scopus, and Google scholar were systematically searched from inception up to June 2020. Inter-study heterogeneity was also assessed using Cochrane’s <i>Q</i> test and the <i>I</i><sup>2</sup> statistic. Afterward, the random-effects model was used to pool the weighted mean differences (WMDs) and the corresponding 95% confidence intervals (CIs). Eleven articles that reported second-trimester UCA of 5,061 pregnancies were included in this study. Our meta-analysis results indicate that a wider UCA significantly increases the risk of sPTB in following cases: all pregnancies (WMD = 15.25, 95% CI: 11.78–18.72, <i>p</i> &#x3c; 0.001; <i>I</i><sup>2</sup> = 75.9%, <i>p</i> &#x3c; 0.001), singleton (WMD = 14.43, 95% CI: 8.79–20.06, <i>p</i> &#x3c; 0.001; <i>I</i><sup>2</sup> = 82.4%, <i>p</i> &#x3c; 0.001), and twin pregnancies (WMD = 15.14, 95% CI: 13.42–16.87, <i>p</i> &#x3c; 0.001; <i>I</i><sup>2</sup> = 0.0%, <i>p</i> = 0.464). A wider ultrasound-measured UCA in the second trimester seems to be associated with the increased risk of sPTB in both singleton and twin pregnancies, which reinforces the clinical evidence that UCA has the potential to be used as a predictive marker of sPTB.


2017 ◽  
Vol 30 (24) ◽  
pp. 2918-2925 ◽  
Author(s):  
Gabriele Saccone ◽  
Andrea Ciardulli ◽  
Serena Xodo ◽  
Lorraine Dugoff ◽  
Jack Ludmir ◽  
...  

2017 ◽  
Vol 39 (5) ◽  
pp. 392
Author(s):  
Alexander Jarde ◽  
Olha Lutsiv ◽  
Christina K. Park ◽  
Jon Barrett ◽  
Joseph Beyene ◽  
...  

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