scholarly journals OP11.02: Intrauterine transfusion in severe fetal anemia: does peak systolic velocity of middle cerebral artery correlate with fetal hemoglobin?

2018 ◽  
Vol 52 ◽  
pp. 95-95
Author(s):  
J. Lee ◽  
H. Won ◽  
M. Lee ◽  
J. Shim ◽  
P. Lee ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Peak Systolic Velocity ◽  
Fetal Hemoglobin ◽  
Fetal Anemia ◽  
Intrauterine Transfusion

Comparison of the Performances of Middle Cerebral Artery Peak Systolic Velocity and Cardiothoracic Diameter Ratio in Predicting Fetal Anemia: Using Fetal Hemoglobin Bart’s Disease as a Study Model

2021 ◽  
pp. 1-8
Author(s):  
Wisit Chankhunaphas ◽  
Theera Tongsong ◽  
Fuanglada Tongprasert ◽  
Kasemsri Srisupundit ◽  
Suchaya Luewan ◽  
...  
Keyword(s):  
At Risk ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Gestational Age ◽  
Peak Systolic Velocity ◽  
Fetal Hemoglobin ◽  
Diameter Ratio ◽  
Fetal Anemia ◽  
Receiver Operating Characteristic Curves ◽  
Hb Bart's

<b><i>Objective:</i></b> The aim of the study was to compare the performances of cardiothoracic diameter ratio (CTR) and middle cerebral artery peak systolic velocity (MCA-PSV) in predicting fetal hemoglobin (Hb) Bart’s disease and identify the best CTR cut-off for each gestational period. <b><i>Methods:</i></b> Pregnancies at risk of fetal Hb Bart’s disease (gestational ages of 12–36 weeks) were prospectively recruited to undergo ultrasound examination. The measurements of CTR and MCA-PSV were performed and recorded before invasive diagnosis. <b><i>Results:</i></b> During the study period (2005–2019), a total of 1,717 pregnancies at risk of fetal Hb Bart’s disease met the inclusion criteria and were available for analysis, including 329 (19.2%) fetuses with Hb Bart’s disease. The mean gestational age at the time of diagnosis was 19.30 ± 5.6 weeks, ranging from 12 to 36 weeks. The overall performance of CTR <i>Z</i>-scores is superior to that of MCA-PSV multiple of median (MoM) values; area under curve of 0.866 versus 0.711, <i>p</i> value &#x3c;0.001. The diagnostic indices of CTR and MCA-PSV are increased with gestational age. Based on receiver operating characteristic curves of CTR <i>Z</i>-scores, the best cut-off points of CTR at 12–14, 15–17, 18–20, 21–23, and ≥24 weeks are 0.48, 0.49, 0.50, 0.51, and 0.54, respectively. The best cut-off of MCA-PSV is 1.3 MoM, giving the best performance at 21–23 weeks with a sensitivity of 91.8% and specificity of 85.5%. <b><i>Conclusion:</i></b> The performance of CTR is much better than MCA-PSV in predicting fetal anemia caused by Hb Bart’s disease. Nevertheless, whether this can be reproduced in anemia due to other causes, like isoimmunization, is yet to be explored.

Middle Cerebral Artery Doppler Changes following Fetal Transfusion Performed with and without Fetal Anesthesia

2017 ◽  
Vol 35 (07) ◽  
pp. 682-687 ◽  
Author(s):  
Kristen Uquillas ◽  
Myrna Aboudiab ◽  
Lisa Korst ◽  
Arlyn Llanes ◽  
Brendan Grubbs ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Umbilical Cord ◽  
Cerebral Artery ◽  
Gestational Age ◽  
Peak Systolic Velocity ◽  
Fetal Anemia ◽  
Intravenous Anesthesia ◽  
Intrauterine Transfusion ◽  
The Difference ◽  
The Relationship

Objective The objective of this study was to test the association between fetal intravenous anesthesia and the change in middle cerebral artery peak systolic velocity (MCA-PSV) in patients undergoing intrauterine transfusion (IUT) for suspected fetal anemia. Study Design We retrospectively examined data from all patients who underwent IUT via umbilical cord route from 2007 to 2016. We calculated the change of the MCA-PSV multiple of median (MoM) as the difference in MCA-PSV MoM between the pre- and immediate postoperative measurements for the first IUT. The change in MCA-PSV MoM was compared between those who did and did not receive fetal anesthesia using Kruskal–Wallis' testing. Results Of 62 patients, 37 (59.7%) received intravenous fetal anesthesia and 25 (40.3%) did not. The change in MCA-PSV MoM did not differ between those who did and did not receive fetal anesthesia (median: 0.57 [interquartile range, IQR: +0.42 to +0.76] vs. median 0.57 [IQR: +0.40 to +0.81], p = 1.000). The relationship remained insignificant when stratifying by gestational age, length of procedure, initial MCA-PSV, and when excluding hydropic fetuses. Conclusion Among women undergoing IUT, there was no evidence that the use of fetal anesthesia was associated with a change in the pre- versus postoperative change in MCA-PSV MoM.

scholarly journals OP24.07: Prediction of moderate fetal anemia risk by longitudinal assessments of middle cerebral artery peak systolic velocity

2010 ◽  
Vol 36 (S1) ◽  
pp. 123-123
Author(s):  
M. Pětroš ◽  
M. Liška ◽  
D. Matura ◽  
P. Kordoš ◽  
O. Šimetka ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Peak Systolic Velocity ◽  
Fetal Anemia

Suspected hemorrhagic ovarian cyst causing fetal anemia measured by the peak systolic velocity in the middle cerebral artery

2013 ◽  
Vol 171 (1) ◽  
pp. 187-188 ◽  
Author(s):  
Sandy A. Hanssens ◽  
Capucine D. Coulon ◽  
Elodie M. Clouqueur ◽  
Philippe L. Bourgeot ◽  
Pascal G. Vaast ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Ovarian Cyst ◽  
Peak Systolic Velocity ◽  
Fetal Anemia

scholarly journals Prediction of Fetal Anemia by Middle Cerebral Artery Peak Systolic Velocity in Pregnancies Complicated by Rhesus Isoimmunization

2003 ◽  
Vol 23 (7) ◽  
pp. 536-540 ◽  
Author(s):  
M M Alshimmiri ◽  
M S Hamoud ◽  
E A Al-Saleh ◽  
K Y Mujaibel ◽  
J A Al-Harmi ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Peak Systolic Velocity ◽  
Fetal Anemia
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