scholarly journals OP01.04: Prevalence of chromosome abnormalities and uptake of further testing after positive combined first trimester screening in Chinese women: a retrospective cohort study

2018 ◽  
Vol 52 ◽  
pp. 67-67
Author(s):  
A. Mak ◽  
T. Ma ◽  
K. Chan ◽  
A. Kan ◽  
H.Y.M. Tang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Chinese Women ◽  
First Trimester ◽  
Chromosome Abnormalities ◽  
First Trimester Screening ◽  
Trimester Screening

scholarly journals Baseline Levels of Serum Progesterone and the First Trimester Pregnancy Outcome in Women with Threatened Abortion: A Retrospective Cohort Study

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Yongshi Deng ◽  
Chi Chen ◽  
Siyun Chen ◽  
Guanyan Mai ◽  
Xiuping Liao ◽  
...  
Keyword(s):  
Cohort Study ◽  
Pregnancy Outcome ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
First Trimester ◽  
Outcome Variable ◽  
Serum Progesterone ◽  
First Trimester Pregnancy ◽  
Trimester Pregnancy ◽  
Threatened Abortion

Objective. The relationship between serum progesterone and the first trimester pregnancy outcome of threatened abortion is still controversial. Therefore, we aimed to further study the association between these two parameters. Methods. The present study is an observational retrospective cohort study. A total of 726 participants who had threatened abortion from a hospital in Guangdong, China, were included in this study from 17th August 2011 to 30th October 2018. The exposure variable and the outcome variable were serum progesterone measured at baseline and early pregnancy outcome, respectively. Covariates involved in this study included patients’ basic demographics, obstetric history, and clinical information. Results. A negative association and a saturation effect were detected between serum progesterone and the first trimester pregnancy outcome. When progesterone <90.62 nmol/L, an increase in 1 nmol/L of serum progesterone was associated with 3% decrease of the risk of miscarriage (OR: 0.97, 95% CI: 0.95-0.98). Conclusion. There was a greater risk of abortion when the serum progesterone level was less than 90.62 nmol/L. Our findings can better assist the clinician in understanding patients’ conditions and making medical decisions.

scholarly journals The association between periconceptional folic acid supplementation and the risk of preterm birth: a population-based retrospective cohort study of 200,000 women in China

2020 ◽  
Author(s):  
Yu Wu ◽  
Yanling Yuan ◽  
Cai Kong ◽  
Qiuyue Ma ◽  
Hanfeng Ye ◽  
...  
Keyword(s):  
Cohort Study ◽  
Folic Acid ◽  
Preterm Birth ◽  
Retrospective Cohort Study ◽  
Lower Risk ◽  
Retrospective Cohort ◽  
Chinese Women ◽  
Population Based ◽  
Menstrual Period ◽  
Last Menstrual Period

Abstract Purpose The aim of this study was to examine the association between periconceptional folic acid (FA) supplementation and risk of preterm birth. Methods We conducted a retrospective cohort study in women aged 18–49 who participated in the NFPHEP from 2010 to 2018, and had a singleton livebirth in 129 counties in southwest China. Participants were divided into four groups according to the time period starting FA use: no use, after the last menstrual period, at least 1–2 months before the last menstrual period, at least 3 months before the last menstrual period. The outcomes were preterm birth (gestation < 37 weeks) and early preterm birth (gestation < 34 weeks). Results 201,477 women were included and 191,809 (95.2%) had taken FA during periconception. Compared with women who did not take FA, women who started taking FA 1–2 months before their last menstrual period had a 15% lower risk of preterm birth (aOR = 0.85, 95% CI 0.79–0.92), and women who started taking FA at least 3 months before their last menstrual period had a 20% lower risk of preterm birth (aOR = 0.80, 95% CI 0.75–0.87), but women who started taking FA after their last menstrual period did not appear to reduce the risk of preterm birth. Conclusions In this study of 200,000 Chinese women, periconceptional supplementation with FA was associated with a lower risk of preterm birth. Women who started taking FA at least 3 months before their last menstrual period were more likely to reduce the risk of preterm birth.

Sign in / Sign up

Export Citation Format

Share Document