scholarly journals OC08.02: A preoperative risk model with ultrasound variables to assess lymph node metastasis in endometrial cancer patients: a model development and validation study by the IETA group

2018 ◽  
Vol 52 ◽  
pp. 17-17
Author(s):  
L. Eriksson ◽  
E. Epstein ◽  
A.C. Testa ◽  
D. Fischerová ◽  
L. Valentin ◽  
...  
Author(s):  
Hui-Hua Chen ◽  
Wan-Hua Ting ◽  
Hsu-Dong Sun ◽  
Ming-Chow Wei ◽  
Ho-Hsiung Lin ◽  
...  

Background: to elucidate the predictors of progression-free survival (PFS) and overall survival (OS) in high-risk endometrial cancer patients. Methods: the medical records of all consecutivewomen with high-risk endometrial cancer were reviewed. Results: among 92 high-risk endometrial cancer patients, 30 women experienced recurrence, and 21 women died. The 5-year PFS and OS probabilities were 65.3% and 75.9%, respectively. Multivariable Cox regression revealed that body mass index (hazard ratio (HR) = 1.11), paraaortic lymph node metastasis (HR = 11.11), lymphovascular space invasion (HR = 5.61), and sandwich chemoradiotherapy (HR = 0.15) were independently predictors of PFS. Body mass index (HR = 1.31), paraaortic lymph node metastasis (HR = 32.74), non-endometrioid cell type (HR = 11.31), and sandwich chemoradiotherapy (HR = 0.07) were independently predictors of OS. Among 51 women who underwent sandwich (n = 35) or concurrent (n = 16) chemoradiotherapy, the use of sandwich chemoradiotherapy were associated with better PFS (adjusted HR = 0.26, 95% CI = 0.08–0.87, p = 0.03) and OS (adjusted HR = 0.11, 95% CI = 0.02–0.71, p = 0.02) compared with concurrent chemoradiotherapy. Conclusion: compared with concurrent chemoradiotherapy, sandwich chemoradiotherapy was associated with better PFS and OS in high-risk endometrial cancer patients. In addition, high body mass index, paraaortic lymph node metastasis, and non-endometrioid cell type were also predictors of poor OS in high-risk endometrial cancer patients.


2017 ◽  
Vol 116 (2) ◽  
pp. 220-226 ◽  
Author(s):  
Glauco Baiocchi ◽  
Carlos Chaves Faloppa ◽  
Henrique Mantoan ◽  
Willian Ricardo Camarço ◽  
Levon Badiglian-Filho ◽  
...  

2007 ◽  
Vol 104 (3) ◽  
pp. 623-628 ◽  
Author(s):  
Yukiharu Todo ◽  
Kazuhira Okamoto ◽  
Masaru Hayashi ◽  
Shinichiro Minobe ◽  
Eiji Nomura ◽  
...  

Clinics ◽  
2017 ◽  
Vol 72 (1) ◽  
pp. 30-35 ◽  
Author(s):  
C Anton ◽  
AS Silva ◽  
EC Baracat ◽  
NU Dogan ◽  
C Köhler ◽  
...  

2016 ◽  
Vol 142 (2) ◽  
pp. 273-277 ◽  
Author(s):  
Kazuaki Imai ◽  
Hisamori Kato ◽  
Kayoko Katayama ◽  
Kazuho Nakanishi ◽  
Aiko Kawano ◽  
...  

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