scholarly journals OC04.04: Is the introduction of magnetic resonance in the diagnostic workout of adnexal masses just an increase of costs when IOTA Simple Rules are applied?

2018 ◽  
Vol 52 ◽  
pp. 8-8
Author(s):  
S. Guerriero ◽  
A. Piras ◽  
S. Ajossa ◽  
M. Pascual ◽  
I. Rodríguez ◽  
...  
2019 ◽  
Vol 45 (10) ◽  
pp. 3218-3229 ◽  
Author(s):  
Patrick Nunes Pereira ◽  
Luís Otavio Sarian ◽  
Adriana Yoshida ◽  
Karla Galvão Araújo ◽  
Ana Carolina Baião Silva ◽  
...  

GYNECOLOGY ◽  
2014 ◽  
Vol 16 (1) ◽  
pp. 69-72
Author(s):  
S.A. Martynov ◽  
◽  
L.V. Adamyan ◽  
E.A. Kulabukhova ◽  
P.V. Uchevatkina ◽  
...  

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 414
Author(s):  
Artur Czekierdowski ◽  
Norbert Stachowicz ◽  
Agata Smoleń ◽  
Tomasz Kluz ◽  
Tomasz Łoziński ◽  
...  

Background: To evaluate the accuracy of subjective assessment (SA), the International Ovarian Tumor Analysis (IOTA) group Simple Rules Risk (SRR) and the Assessment of Different NEoplasias in the adneXa (ADNEX) model for the preoperative differentiation of adnexal masses in pregnant women. Methods: The study population comprised 36 pregnant women (median age: 28.5 years old, range: 20–42 years old) with a mean gestation age of 13.5 (range: 8–31) weeks at diagnosis. Tumors were prospectively classified by local sonographers as probably benign or probably malignant using SA. Final tumor histological diagnosis was used as the reference standard in all cases. Logistic regression SRR and ADNEX models were used to obtain a risk score for every case. Serum CA125 and human epidydimis protein 4 (HE4) concentrations were also retrieved and the Risk of Ovarian Malignancy Algorithm (ROMA) value was calculated. The calculated predictive values included positive and negative likelihood ratios of ultrasound and biochemical tests. Results: Final histology confirmed 27 benign and 9 malignant (including 2 borderline) masses. The highest sensitivity (89%) and specificity (70%) were found for the subjective tumor assessment. Although no malignancy was classified as benign using the SRR criteria (sensitivity = 100%), the specificity of this scoring system was only 37%. At the cut-off risk level of >20%, the ADNEX model had a sensitivity of 78% and a specificity of 70%. Serum levels of CA125, HE4 and the ROMA risk model correctly identified adnexal malignant tumors with a sensitivity of 67%, 25% and 25%, respectively. Corresponding specificities were 72%, 100% and 100%, respectively. The highest positive and negative likelihood ratios were found for SA (LR+ = 3.0 and LR− = 0.16, respectively). Overall diagnostic accuracy of all predictive methods used in this study were similar (range: 70–75%) except for SRR (53%). Conclusion: Subjective assessment remains the best predictive method in complex adnexal masses found at prenatal ultrasound in pregnant women. For less experienced sonographers, both the SRR and ADNEX scoring systems may be also used for the characterization of such tumors, while serum tumor markers CA125 and HE4, along with the ROMA algorithm appear to be less accurate.


2005 ◽  
Vol 60 (3) ◽  
pp. 340-348 ◽  
Author(s):  
S.A. Sohaib ◽  
T.D. Mills ◽  
A. Sahdev ◽  
J.A.W. Webb ◽  
P.O. VanTrappen ◽  
...  

2020 ◽  
Author(s):  
Le Qian ◽  
Qinwen Du ◽  
Meijiao Jiang ◽  
Fei Yuan ◽  
Hui Chen ◽  
...  

Abstract Background This study aimed to compare different ultrasound-based International Ovarian Tumor Analysis (IOTA) prediction models, namely, the Simple Rules (SRs) the Assessment of Different NEoplasias in the adneXa (ADNEX) models, and the Risk of Malignancy Index (RMI), for the pre-operative diagnosis of adnexal mass. Methods This single-centre, retrospective study of diagnostic accuracy involved 486 patients. All ultrasound examinations were analyzed and the prediction models were applied. Pathology was the clinical reference standard. The diagnostic performances of prediction models were measured by evaluating receiver-operating characteristic (ROC) curves, sensitivities, specificities, positive and negative predictive values, positive and negative likelihood ratios, and diagnostic odds ratios. Results To discriminate benign and malignant tumours, areas under the ROC curves (AUCs) for ADNEX models were 0.94 (95% CI: 0.92–0.96) with CA125 and 0.94 (95% CI: 0.91–0.96) without CA125, which were significantly higher than the AUCs for RMI I-III: 0.87 (95% CI: 0.83–0.90), 0.83 (95% CI: 0.80–0.86), and 0.82 (95% CI: 0.78–0.86), (all P < 0.0001). At a cut-off of 10%, the ADNEX model with CA125 had the highest sensitivity (0.93; 95% CI: 0.87–0.97) compared with the other models. The SRs model achieved a sensitivity of 0.93 (95% CI: 0.86–0.97) and a specificity of 0.86 (95% CI: 0.82–0.89) when inconclusive diagnoses (11.7%) were classified as malignant. Conclusion ADNEX and SRs models were excellent at characterising adnexal masses which were superior to the RMI in Chinese patients.


2019 ◽  
Vol 05 (02) ◽  
pp. 044-049
Author(s):  
Reddy Ravikanth

Abstract Introduction Magnetic resonance imaging (MRI) is often used in the detection and staging of large pelvic masses. Many large masses in the female pelvis arise from the reproductive organs. These pelvic masses most commonly arise from the uterus, cervix, ovaries, and fallopian tubes. Objective This study was aimed to assess the role of MRI in female pelvic mass lesions. Also, it presents a pictorial review of MRI images of such pelvic masses. Materials and Methods This study was conducted on 50 female patients with clinically suspected pelvic masses at physical examination and referred for MRI at a tertiary care hospital over a 2-year period between July 2017 and June 2019. Results Most common lesions evaluated on imaging were benign uterine lesions (15 cases, 34.09%), benign adnexal lesions (13 cases, 29.54%), malignant adnexal (10 cases, 22.73%), malignant uterine cervical lesions (6 cases, 13.64%); two cases had indeterminate type lesions, two lesions proved to be normal bowel loops on MRI, and in two cases MRI could not be performed. Cystic lesions were commonly seen in adnexa (15 out 21) while solid lesions were common in uterine cervical region (18 out 23). Out of these, 14 were complex cystic adnexal masses and 10 were malignant. Uterine cervical lesions were carcinoma cervix. Better assessment with improved imaging capability was possible on MRI for invasion of surrounding structures in 10 cases, lymphadenopathy in 3 cases, ascites in 13 cases, peritoneal implant in 6 cases, encasement in 1 case, and distant metastases in 1 case. Conclusion In conclusion, pelvic mass lesions in females are more common above the age of 45 years. Adnexal masses are usually cystic, while the uterine masses are solid in texture. As the complexity and size of the cystic adnexal masses increases, there are increased chances of malignancy. Pretreatment staging and assessment of malignancy, invasion of surrounding structures, encasement, invasion of vessels or assessment of lymphadenopathy, peritoneal implant, ascites, and distant metastases are better appreciated by MRI.


2019 ◽  
Vol 22 (2) ◽  
pp. 145-145
Author(s):  
S. Gueriero ◽  
M.A. Pascual ◽  
A. Piras ◽  
E. Musa ◽  
S. Ajossa ◽  
...  

2020 ◽  
Vol 56 (S1) ◽  
pp. 331-331
Author(s):  
J. Alcazar ◽  
E. Chacon ◽  
J. Minguez ◽  
N. Manzour ◽  
I. Carriles ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document