scholarly journals EP06.18: Current prenatal screening efficacy of Trisomy 21, 18 13 in the Taiwan: a 6-year national registry study

2017 ◽  
Vol 50 ◽  
pp. 288-288
Author(s):  
C. Hsiao ◽  
Chen
Keyword(s):  
Trisomy 21 ◽  
Prenatal Screening ◽  
National Registry ◽  
Registry Study

scholarly journals Efficiency of non-invasive prenatal screening in pregnant women at advanced maternal age

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hui Zhu ◽  
Xiaoxiao Jin ◽  
Yuqing Xu ◽  
Weihua Zhang ◽  
Xiaodan Liu ◽  
...  
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Predictive Value ◽  
Trisomy 21 ◽  
Maternal Age ◽  
Prenatal Screening ◽  
Advanced Maternal Age ◽  
Youden Index ◽  
Non Invasive ◽  
Sensitivity Specificity

Abstract Background Non-invasive prenatal screening (NIPS) is widely used as the alternative choice for pregnant women at high-risk of fetal aneuploidy. However, whether NIPS has a good detective efficiency for pregnant women at advanced maternal age (AMA) has not been fully studied especially in Chinese women. Methods Twenty-nine thousand three hundred forty-three pregnant women at AMA with singleton pregnancy who received NIPS and followed-up were recruited. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV), receiver operating characteristic (ROC) curves and the Youden Index for detecting fetal chromosomal aneuploidies were analyzed. The relationship between maternal age and common fetal chromosomal aneuploidy was observed. Results The sensitivity, specificity, PPV, NPV of NIPS for detecting fetal trisomy 21 were 99.11, 99.96, 90.98, and 100%, respectively. These same parameters for detecting fetal trisomy 18 were 100, 99.94, 67.92, and 100%, respectively. Finally, these parameters for detecting trisomy 13 were 100, 99.96, 27.78, and 100%, respectively. The prevalence of fetal trisomy 21 increased exponentially with maternal age. The high-risk percentage incidence rate of fetal trisomy 21 was significantly higher in the pregnant women at 37 years old or above than that in pregnant women at 35 to 37 years old. (Youden index = 37). Conclusion It is indicated that NIPS is an effective prenatal screening method for pregnant women at AMA.

scholarly journals Unequal physical activity among children with cerebral palsy in Sweden—A national registry study

2021 ◽  
Vol 4 (3) ◽  
Author(s):  
Frida Degerstedt ◽  
Martin Björklund ◽  
Britt‐Inger Keisu ◽  
Birgit Enberg
Keyword(s):  
Physical Activity ◽  
Cerebral Palsy ◽  
National Registry ◽  
Registry Study ◽  
Children With Cerebral Palsy

scholarly journals Optimization of regional median equations of prenatal screening markers for trisomy 21 in a Chinese population

Medicine ◽  
2018 ◽  
Vol 97 (35) ◽  
pp. e12045
Author(s):  
Liangpu Xu ◽  
Hailong Huang ◽  
Lin Zheng ◽  
Deqin He ◽  
Na Lin ◽  
...  
Keyword(s):  
Trisomy 21 ◽  
Chinese Population ◽  
Prenatal Screening

scholarly journals Risk factors of suicide mortality among multiple attempters: A national registry study in Taiwan

2016 ◽  
Vol 115 (5) ◽  
pp. 364-371 ◽  
Author(s):  
I-Ming Chen ◽  
Shih-Cheng Liao ◽  
Ming-Been Lee ◽  
Chia-Yi Wu ◽  
Po-Hsien Lin ◽  
...  
Keyword(s):  
Risk Factors ◽  
National Registry ◽  
Suicide Mortality ◽  
Registry Study

Suicide Among Holocaust Survivors: A National Registry Study

2021 ◽  
pp. 1-12
Author(s):  
Ido Lurie ◽  
Nehama Goldberger ◽  
Adi Gur Orr ◽  
Ziona Haklai ◽  
Shlomo Mendlovic
Keyword(s):  
Holocaust Survivors ◽  
National Registry ◽  
Registry Study

Determination of sensitivity and specificity of a novel gene dosage assay for prenatal screening of trisomy 21 syndrome

2012 ◽  
Vol 45 (3) ◽  
pp. 267-271 ◽  
Author(s):  
Ahmad Reza Kamyab ◽  
Fahimeh Shahrokhi ◽  
Elmira Shamsian ◽  
Mina Hayat Nosaied ◽  
Parvin Dibajnia ◽  
...  
Keyword(s):  
Sensitivity And Specificity ◽  
Trisomy 21 ◽  
Prenatal Screening ◽  
Gene Dosage ◽  
Novel Gene
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