scholarly journals OP07.10: Transvaginal ultrasound for preoperative assessment of myometrial invasion in patients with endometrial cancer: a systematic review and meta-analysis

2015 ◽  
Vol 46 ◽  
pp. 73-73 ◽  
Author(s):  
J. Alcazar ◽  
R. Orozco ◽  
T. Martinez-Astorquiza Corral ◽  
L. Juez ◽  
J. Utrilla-Layna ◽  
...  
Keyword(s):  
Systematic Review ◽  
Endometrial Cancer ◽  
Meta Analysis ◽  
Transvaginal Ultrasound ◽  
Myometrial Invasion ◽  
Preoperative Assessment

scholarly journals Transvaginal three-dimensional ultrasound for preoperative assessment of myometrial invasion in patients with endometrial cancer: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Tatiana Costas ◽  
Rocío Belda ◽  
Juan Luis Alcazar
Keyword(s):  
Endometrial Cancer ◽  
Diagnostic Accuracy ◽  
Frozen Section ◽  
Meta Analysis ◽  
Transvaginal Ultrasound ◽  
Three Dimensional ◽  
Myometrial Invasion ◽  
Negative Likelihood Ratio ◽  
Preoperative Assessment ◽  
Standard Material

Aim: The aim of this meta-analysis is to evaluate the diagnostic accuracy of three-dimensional transvaginal ultrasound subjective assessment (3D-TVS) in the preoperative detection of deep myometrial invasion (MI) in patients with endometrial cancer, using definitive frozen section diagnosis after surgery as the reference standard. Material and methods: A search for studies evaluating the role of 3D-TVS for assessing myometrial invasion in endometrial cancer from January 1990 to Novem-ber 2020 was performed in PubMed/MEDLINE and Web of Science. The Quality Assessment of Diagnostic Accuracy Studies 2 evaluated the quality of the studies (QUADAS-2). All analyses were performed using MIDAS and METANDI commands. Results: Nine studies comprising 581 women were included. The mean prevalence of deep MI was 39.8%. QUADAS as-sessment showed that most studies had a high risk for the patient selection domain. Overall, the pooled estimated sensitivity, specificity, positive likelihood and negative likelihood ratio of 3D-TVS for detecting deep MI were 84% (95% CI, 73-90%), 82% (95% CI, 75-88%), 5 (95% CI, 3.1-7.1) and 0.20 95% CI, 0.11-0.35). respectively. Conclusions: 3D-TVS has an accept-able diagnostic performance for detecting MI in women with endometrial cancer.

MR diffusion imaging for preoperative staging of myometrial invasion in patients with endometrial cancer: a systematic review and meta-analysis

2014 ◽  
Vol 24 (6) ◽  
pp. 1327-1338 ◽  
Author(s):  
Anita Andreano ◽  
Gilda Rechichi ◽  
Paola Rebora ◽  
Sandro Sironi ◽  
Maria Grazia Valsecchi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Endometrial Cancer ◽  
Meta Analysis ◽  
Diffusion Imaging ◽  
Preoperative Staging ◽  
Myometrial Invasion ◽  
Mr Diffusion

Preoperative Assessment of Cervical Involvement in Endometrial Cancer by Transvaginal Ultrasound and Magnetic Resonance Imaging: A Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Juan Luis Alcazar ◽  
Patricia Carazo ◽  
Leyre Pegenaute ◽  
Elena Gurrea ◽  
Irene Campos ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Endometrial Cancer ◽  
Magnetic Resonance ◽  
Diagnostic Accuracy ◽  
Sensitivity And Specificity ◽  
Meta Analysis ◽  
Transvaginal Ultrasound ◽  
Preoperative Assessment ◽  
Resonance Imaging ◽  
Cervical Involvement

Abstract Objective To compare the diagnostic accuracy of transvaginal ultrasound (TVS) and magnetic resonance imaging (MRI) for detecting cervical infiltration by endometrial carcinoma using meta-analysis assessment. Methods An extensive search of papers comparing TVS and MRI for assessing cervical infiltration in endometrial cancer in the same set of patients was performed in Medline (Pubmed), Web of Science, and the Cochrane Database. Quality was assessed using QUADAS-2 tool (Quality Assessment of Diagnostic Accuracy Studies-2). Quantitative meta-analysis was performed. Results Our extended search identified 12 articles that used both techniques in the same set of patients and were included in the meta-analysis. The risk of bias for most studies was high for patient selection and index tests in QUADAS-2. Overall, the pooled estimated sensitivity and specificity for diagnosing cervical infiltration in women with endometrial cancer were identical for both techniques [69 % (95 % CI, 51 %–82 %) and 93 % (95 % CI, 90 %–95 %) for TVS, and 69 % (95 % CI, 57 %–79 %) and 91 % (95 % CI, 90 %–95 %) for MRI, respectively]. No statistical differences were found when comparing both methods. Heterogeneity was high for sensitivity and moderate for specificity when analyzing TVS and moderate for both sensitivity and specificity in the case of MRI. Conclusion TVS and MRI showed very similar diagnostic performance for diagnosing cervical involvement in women with endometrial cancer.

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