scholarly journals Development and validation of a tool incorporating quantitative fetal fibronectin to predict spontaneous preterm birth in symptomatic women

2016 ◽  
Vol 47 (2) ◽  
pp. 210-216 ◽  
Author(s):  
K. Kuhrt ◽  
N. Hezelgrave ◽  
C. Foster ◽  
P. T. Seed ◽  
A. H. Shennan
Keyword(s):  
Preterm Birth ◽  
Spontaneous Preterm Birth ◽  
Fetal Fibronectin ◽  
Development And Validation

scholarly journals Biochemical Markers of Spontaneous Preterm Birth in Asymptomatic Women

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Ronna L. Chan
Keyword(s):  
Preterm Birth ◽  
Biochemical Markers ◽  
Preterm Births ◽  
Future Research ◽  
Spontaneous Preterm Birth ◽  
Fetal Fibronectin ◽  
Potential Risk Factors ◽  
Underlying Mechanisms ◽  
Development And Validation ◽  
Asymptomatic Women

Preterm birth is a delivery that occurs at less than 37 completed weeks of gestation and it is associated with perinatal morbidity and mortality. Spontaneous preterm birth accounts for up to 75% of all preterm births. A number of maternal or fetal characteristics have been associated with preterm birth, but the use of individual or group biochemical markers have advanced some of the understanding on the mechanisms leading to spontaneous preterm birth. This paper provides a summary on the current literature on the use of biochemical markers in predicting spontaneous preterm birth in asymptomatic women. Evidence from the literature suggests fetal fibronectin, cervical interleukin-6, andα-fetoprotein as promising biochemical markers in predicting spontaneous preterm birth in asymptomatic women. The role of gene-gene and gene-environment interactions, as well as epigenetics, has the potential to further elucidate and improve understanding of the underlying mechanisms or pathways of spontaneous preterm birth. Refinement in study design and methodology is needed in future research for the development and validation of individual or group biochemical marker(s) for use independently or in conjunction with other potential risk factors such as genetic variants and environmental and behavioral factors in predicting spontaneous preterm birth across diverse populations.

Prediction of spontaneous preterm birth using quantitative fetal fibronectin after recent sexual intercourse

2015 ◽  
Vol 212 (1) ◽  
pp. 89.e1-89.e5 ◽  
Author(s):  
James S. McLaren ◽  
Natasha L. Hezelgrave ◽  
Homira Ayubi ◽  
Paul T. Seed ◽  
Andrew H. Shennan
Keyword(s):  
Preterm Birth ◽  
Sexual Intercourse ◽  
Spontaneous Preterm Birth ◽  
Fetal Fibronectin

Prediction of spontaneous preterm birth in asymptomatic twin pregnancies with the use of combined fetal fibronectin and cervical length

2009 ◽  
Vol 201 (3) ◽  
pp. 313.e1-313.e5 ◽  
Author(s):  
Nathan S. Fox ◽  
Daniel H. Saltzman ◽  
Chad K. Klauser ◽  
Danielle Peress ◽  
Christina V. Gutierrez ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Cervical Length ◽  
Spontaneous Preterm Birth ◽  
Fetal Fibronectin ◽  
Twin Pregnancies

The preterm prediction study: Fetal fibronectin testing and spontaneous preterm birth

1996 ◽  
Vol 87 ◽  
pp. 643-648 ◽  
Author(s):  
R GOLDENBERG ◽  
B MERCER ◽  
P MEIS ◽  
R COPPER ◽  
A DAS ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Spontaneous Preterm Birth ◽  
Fetal Fibronectin
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