Re: Ultrasound guidance during embryo transfer: a systematic review and meta-analysis of randomized controlled trials. D. M. Teixeira, L. A. Dassunção, C. V. R. Vieira, M. A. P. Barbosa, M. A. Coelho Neto, C. O. Nastri and W. P. Martins. Ultrasound Obstet

2015 ◽  
Vol 45 (2) ◽  
pp. 131-131 ◽  
Author(s):  
A. Drakeley
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Embryo Transfer ◽  
Ultrasound Guidance ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled

scholarly journals Ultrasound guidance during embryo transfer: a systematic review and meta-analysis of randomized controlled trials

2015 ◽  
Vol 45 (2) ◽  
pp. 139-148 ◽  
Author(s):  
D. M. Teixeira ◽  
L. A. Dassunção ◽  
C. V. R. Vieira ◽  
M. A. P. Barbosa ◽  
M. A. Coelho Neto ◽  
...  
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Embryo Transfer ◽  
Ultrasound Guidance ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled

scholarly journals Sildenafil Supplementation for Women Undergoing Infertility Treatments: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2021 ◽  
Vol 10 (19) ◽  
pp. 4346
Author(s):  
Loris Marin ◽  
Alessandra Andrisani ◽  
Luciana Bordin ◽  
Francesco Dessole ◽  
Marco Noventa ◽  
...  
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Pregnancy Rate ◽  
Embryo Transfer ◽  
Endometrial Thickness ◽  
Meta Analysis ◽  
Frozen Embryo Transfer ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Infertility Treatments

The aim of this systematic review and meta-analysis is to summarize data on the effectiveness of Sildenafil supplementation for women undergoing assisted reproduction techniques. This meta-analysis of randomized controlled trials (RCTs) evaluates the effects of Sildenafil administration during infertility treatments compared with a control group in infertile women. Outcomes evaluated were endometrial thickness (ETh) and the clinical pregnancy rate (CPR). The chemical pregnancy rate (ChPR) was also evaluated. Pooled results were expressed as the risk ratio (RR) or mean differences (MD) with a 95% confidence interval (95% CI). Women undergoing ovulation induction who received Sildenafil showed higher ETh and a higher CPR in comparison to controls. In this group, both the ETh and ChPR resulted in significantly higher values only with delayed start administration. Women undergoing fresh or frozen embryo transfer who received Sildenafil showed no significant advantages regarding ETh and CPR in comparison to controls. In this group, we found a significantly higher ChPR in women receiving Sildenafil. A subgroup analysis revealed significant advantages regarding ETh with oral administration for women undergoing fresh or frozen embryo transfer. Sildenafil therapy appears to improve endometrial thickness and pregnancy rate in women undergoing timed intercourses but it resulted not effective in IUI and IVF treatments. Further RCTs with rigorous methodology are still mandatory.

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