P07.07: Predictive value of peak systolic velocity in the middle cerebral artery to detect fetal anemia in red-cell alloimmunized pregnancies beyond 35 weeks

2004 ◽  
Vol 24 (3) ◽  
pp. 309-309 ◽  
Author(s):  
J. E. Sanin-Blair ◽  
A. Bonato ◽  
E. Hernández-Andrade ◽  
J. Sagala ◽  
L. Cabero ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Predictive Value ◽  
Peak Systolic Velocity ◽  
Fetal Anemia ◽  
Red Cell

scholarly journals OP24.07: Prediction of moderate fetal anemia risk by longitudinal assessments of middle cerebral artery peak systolic velocity

2010 ◽  
Vol 36 (S1) ◽  
pp. 123-123
Author(s):  
M. Pětroš ◽  
M. Liška ◽  
D. Matura ◽  
P. Kordoš ◽  
O. Šimetka ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Peak Systolic Velocity ◽  
Fetal Anemia

Suspected hemorrhagic ovarian cyst causing fetal anemia measured by the peak systolic velocity in the middle cerebral artery

2013 ◽  
Vol 171 (1) ◽  
pp. 187-188 ◽  
Author(s):  
Sandy A. Hanssens ◽  
Capucine D. Coulon ◽  
Elodie M. Clouqueur ◽  
Philippe L. Bourgeot ◽  
Pascal G. Vaast ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Ovarian Cyst ◽  
Peak Systolic Velocity ◽  
Fetal Anemia

scholarly journals Prediction of Fetal Anemia by Middle Cerebral Artery Peak Systolic Velocity in Pregnancies Complicated by Rhesus Isoimmunization

2003 ◽  
Vol 23 (7) ◽  
pp. 536-540 ◽  
Author(s):  
M M Alshimmiri ◽  
M S Hamoud ◽  
E A Al-Saleh ◽  
K Y Mujaibel ◽  
J A Al-Harmi ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Peak Systolic Velocity ◽  
Fetal Anemia

Comparison of the Performances of Middle Cerebral Artery Peak Systolic Velocity and Cardiothoracic Diameter Ratio in Predicting Fetal Anemia: Using Fetal Hemoglobin Bart’s Disease as a Study Model

2021 ◽  
pp. 1-8
Author(s):  
Wisit Chankhunaphas ◽  
Theera Tongsong ◽  
Fuanglada Tongprasert ◽  
Kasemsri Srisupundit ◽  
Suchaya Luewan ◽  
...  
Keyword(s):  
At Risk ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Gestational Age ◽  
Peak Systolic Velocity ◽  
Fetal Hemoglobin ◽  
Diameter Ratio ◽  
Fetal Anemia ◽  
Receiver Operating Characteristic Curves ◽  
Hb Bart's

<b><i>Objective:</i></b> The aim of the study was to compare the performances of cardiothoracic diameter ratio (CTR) and middle cerebral artery peak systolic velocity (MCA-PSV) in predicting fetal hemoglobin (Hb) Bart’s disease and identify the best CTR cut-off for each gestational period. <b><i>Methods:</i></b> Pregnancies at risk of fetal Hb Bart’s disease (gestational ages of 12–36 weeks) were prospectively recruited to undergo ultrasound examination. The measurements of CTR and MCA-PSV were performed and recorded before invasive diagnosis. <b><i>Results:</i></b> During the study period (2005–2019), a total of 1,717 pregnancies at risk of fetal Hb Bart’s disease met the inclusion criteria and were available for analysis, including 329 (19.2%) fetuses with Hb Bart’s disease. The mean gestational age at the time of diagnosis was 19.30 ± 5.6 weeks, ranging from 12 to 36 weeks. The overall performance of CTR <i>Z</i>-scores is superior to that of MCA-PSV multiple of median (MoM) values; area under curve of 0.866 versus 0.711, <i>p</i> value &#x3c;0.001. The diagnostic indices of CTR and MCA-PSV are increased with gestational age. Based on receiver operating characteristic curves of CTR <i>Z</i>-scores, the best cut-off points of CTR at 12–14, 15–17, 18–20, 21–23, and ≥24 weeks are 0.48, 0.49, 0.50, 0.51, and 0.54, respectively. The best cut-off of MCA-PSV is 1.3 MoM, giving the best performance at 21–23 weeks with a sensitivity of 91.8% and specificity of 85.5%. <b><i>Conclusion:</i></b> The performance of CTR is much better than MCA-PSV in predicting fetal anemia caused by Hb Bart’s disease. Nevertheless, whether this can be reproduced in anemia due to other causes, like isoimmunization, is yet to be explored.

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