scholarly journals OC06.05: Conservative management and ultrasonographic longitudinal follow-up of borderline ovarian tumor recurrences after fertility sparing surgery

2014 ◽  
Vol 44 (S1) ◽  
pp. 14-15
Author(s):  
D. Franchi ◽  
A.C. Testa ◽  
S. Boveri ◽  
R. Davide ◽  
S. Mario ◽  
...  
Keyword(s):  
Conservative Management ◽  
Ovarian Tumor ◽  
Borderline Ovarian Tumor ◽  
Fertility Sparing Surgery ◽  
Fertility Sparing

Metastasis to sigmoid colon mucosa and submucosa from serous borderline ovarian tumor: response to hormone therapy

2006 ◽  
Vol 16 (Suppl 1) ◽  
pp. 295-299 ◽  
Author(s):  
E. J. Lee ◽  
M. T. Deavers ◽  
J. I. Hughes ◽  
J. H. Lee ◽  
J. J. Kavanagh
Keyword(s):  
Hormone Therapy ◽  
Sigmoid Colon ◽  
Ovarian Tumor ◽  
Tumor Response ◽  
Metastatic Lesion ◽  
Screening Colonoscopy ◽  
Borderline Ovarian Tumor ◽  
Colon Mucosa ◽  
Metastatic Sites

Distant metastasis to sites other than lymph nodes of borderline ovarian tumor is rare. We describe a case metastasized to sigmoid colon mucosa and submucosa. The metastatic lesion was detected incidentally by screening colonoscopy 7 years after the patient was treated for the primary tumor. The metastatic lesion responded well to treatment with oral Arimidex 1 mg/day. A follow-up colonoscopy with biopsy and imaging studies after 3 months of treatment revealed no evidence of disease in the sigmoid colon. This case showed that the sigmoid colon mucosa and submucosa should be considered as one of distant metastatic sites of a serous borderline ovarian tumor and the favorable response to Arimidex provides support the use of hormone therapy in women with serous borderline ovarian tumor.

scholarly journals Yolk sac tumor in an antenatal patient: a challenging case

2018 ◽  
Vol 7 (10) ◽  
pp. 4318
Author(s):  
Anu Namgyal ◽  
Anjali Soni ◽  
Suresh Verma ◽  
Indu Chauhan ◽  
Shikha Sharma ◽  
...  
Keyword(s):  
Ovarian Neoplasms ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Common Occurrence ◽  
Stage Iiic ◽  
Adnexal Masses ◽  
Antenatal Ultrasound ◽  
Fertility Sparing Surgery ◽  
Fertility Sparing

Pregnancy complicated with adnexal masses is a very common occurrence. However, most of these adnexal masses encountered in pregnancy are benign in nature and are found incidentally during routine antenatal ultrasound. Malignant ovarian neoplasms account for 1%-8% of all persistent adnexal masses diagnosed during pregnancy. Yolk sac tumor (YST) complicating pregnancy is very rare and has no proper guidelines for its diagnosis and management hence causing a therapeutic dilemma for the clinicians. Therefore, an individualised approach is preferred in such cases. It is very important to report such cases for better understanding and management of these cases. Here we present a case report of a 23-year-old primigravida at 30 weeks gestation with yolk sac tumor of right ovary, surgical stage IIIc who responded well to fertility sparing surgery with cisplatin-based combination chemotherapy. She has no evidence of disease post treatment and has been put on regular follow up.

Diethylstilbestrol exposure during pregnancy with primary clear cell carcinoma of the cervix in an 8-year-old granddaughter: a multigenerational effect of endocrine disruptors?

2020 ◽  
Author(s):  
Laura Gaspari ◽  
Françoise Paris ◽  
Nathalie Cassel-Knipping ◽  
Julia Villeret ◽  
Arnauld Verschuur ◽  
...  
Keyword(s):  
Clear Cell ◽  
Causal Link ◽  
Clear Cell Adenocarcinoma ◽  
Fertility Sparing Surgery ◽  
Fertility Sparing ◽  
History Of ◽  
Exposure During Pregnancy ◽  
Multigenerational Effects ◽  
First Time

ABSTRACT To date, vaginal/cervical clear cell adenocarcinoma (CCAC) has not been reported in the granddaughters of women treated with diethylstilbestrol (DES) during pregnancy. We present an 8-year-old girl with a history of severe vaginal bleeding who was diagnosed with cervical CCAC. She underwent fertility-sparing surgery and radiotherapy. No sign of recurrence was detected throughout a 10-year follow-up. Her grandmother had received DES therapy during pregnancy with the patient’s mother. Although no direct causal link is demonstrated, this case raises for the first time, the hypothesis of multigenerational effects of DES in girls and strongly suggests the need to follow the granddaughters of DES-treated women.

Outcomes of fertility-sparing surgery in ovarian juvenile granulosa cell tumor

2019 ◽  
Vol 29 (4) ◽  
pp. 787-791 ◽  
Author(s):  
Dan Zhao ◽  
Yan Song ◽  
Yanan Zhang ◽  
Bin Li
Keyword(s):  
Granulosa Cell ◽  
Disease Onset ◽  
Granulosa Cell Tumor ◽  
Cell Tumor ◽  
Fertility Sparing Surgery ◽  
Juvenile Granulosa Cell Tumor ◽  
Fertility Sparing ◽  
Mean Size ◽  
The Mean

ObjectiveTo analyze the clinical characteristics, diagnosis, and treatment of ovarian juvenile granulosa cell tumor.MethodsThe clinical and pathological data of six patients with ovarian juvenile granulosa cell tumor was collected.ResultsThe mean age of disease onset was 20.5 years (range 12 to 33). All six patients had an adnexal mass located laterally in the pelvis, and two developed ascites. All patients had fertility-sparing surgery with complete staging. The mean size of the tumors was 15.3 cm (range 5 to 35). Ovarian sex cord stromal tumors were diagnosed or highly suspected from the frozen sections for all patients. Five patients received three to six courses of postoperative adjuvant chemotherapy, with three receiving a bleomycin/etoposide/cisplatin regimen and two receiving a paclitaxel/carboplatin regimen. The five stage I patients had no recurrence with 52 to 155 months of follow-up. The patient with stage IIIB disease had a recurrence 55 months’ later and underwent reoperation and chemotherapy. This patient remained disease-free 30 months after the reoperation.ConclusionsFertility-sparing surgery is the treatment of choice for ovarian juvenile granulosa cell tumor and the overall prognosis is good.

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