P13.14: Accuracy of estimation of birthweight in twin compared to singleton pregnancies: the STORK multiple pregnancy cohort

2013 ◽  
Vol 42 (s1) ◽  
pp. 162-163
Author(s):  
A. Khalil ◽  
F. D'Antonio ◽  
T.D. Dias ◽  
D. Cooper ◽  
B. Thilaganathan
1993 ◽  
Vol 5 (2) ◽  
pp. 105-119 ◽  
Author(s):  
James P Neilson ◽  
Caroline A Crowther

Multiple pregnancy is associated with a high rate of perinatal loss – mainly due to preterm labour but with important contributions from fetal malformation, intrauterine growth retardation and twin-twin transfusion syndrome. The overall perinatal mortality rate is consistently around six times that of singleton pregnancies but the rate rises progressively with the number of fetuses. Rates of 63,164,200,214 and 416 per 1000 births have been recently reported for twins, triplets, quadruplets, quintuplets and sextuplets respectively. In addition to these alarming figures, it should be emphasized that the restricted concept of perinatal mortality obscures the real extent of loss. If we include late abortion (after 20 weeks), late neonatal deaths and deaths in infancy from perinatal causes, as well as the usual indices of perinatal mortality (stillbirths and early neonatal deaths) we find that the total loss rate from twin pregnancy alone doubles and may be close to 10%. Although the rate of loss from multiple pregnancies is now substantially higher than that associated with the pregnancies of diabetic women, the challenge of multiple pregnancy has not been met with the same commitment or organisation of specialized perinatal services as has diabetes.


2016 ◽  
Vol 7 (6) ◽  
pp. 678-684 ◽  
Author(s):  
M. J. Davies ◽  
A. R. Rumbold ◽  
M. J. Whitrow ◽  
K. J. Willson ◽  
W. K. Scheil ◽  
...  

The study of very early pregnancy loss is impractical in the general population, but possible amongst infertility patients receiving carefully monitored treatments. We examined the association between fetal loss and the risk of birth defects in the surviving co-twin in a retrospective cohort study of infertility patients within an infertility clinic in South Australia from January 1986 to December 2002, linked to population registries for births, terminations and birth defects. The study population consisted of a total of 5683 births. Births from singleton pregnancies without loss were compared with survivors from (1) pregnancies with an empty fetal sac at 6–8 weeks after embryo transfer, (2) fetal loss subsequent to 8-week ultrasound and (3) multiple pregnancy continuing to birth. Odds ratios (OR) for birth defects were calculated with adjustment for confounders. Amongst infertility patients, the prevalence of birth defects was 7.9% for all twin pregnancies without fetal loss compared with 14.6% in pregnancies in which there had been an empty sac at ultrasound, and 11.6% for pregnancies with fetal loss after 6–8 weeks. Compared with singleton pregnancies without loss, the presence of an empty sac was associated with an increased risk of any defect (OR=1.90, 95% confidence intervals (CI)=1.09–3.30) and with multiple defects (OR=2.87, 95% CI=1.31–6.28). Twin pregnancies continuing to birth without loss were not associated with an overall increased prevalence of defects. We conclude that the observed loss of a co-twin by 6–8 weeks of pregnancy is related to the risk of major birth defects in the survivor.


2012 ◽  
Vol 40 (S1) ◽  
pp. 45-45
Author(s):  
F. D'Antonio ◽  
T. D. Dias ◽  
S. Pescarini ◽  
A. Bhide ◽  
B. Thilaganathan

2016 ◽  
Vol 8 (4) ◽  
pp. 286-289
Author(s):  
Devyani Sawai ◽  
Susheel Kumar Sharma ◽  
Geeta Jain

ABSTRACT Objectives A prospective randomized study was conducted from May 2012 to April 2014 at the Department of Obstetrics and Gynecology, Dr. Sushila Tiwari, Memorial Government Hospital and Government Medical College, Haldwani. Its aim was to study and compare the effects of different doses of intraumbilical oxytocin on 3rd stage of labor with respect to duration and amount of blood loss. Materials and methods The study comprised 200 antenatal cases and included patients with singleton pregnancies at term and spontaneous onset of labor while excluding those with medical disorders of pregnancy, antepartum hemorrhage (APH), multiple pregnancy, polyhydramnios, chorioamnionitis, severe anemia, Rh negative pregnancy, pregnancy-induced hypertension (PIH), prior cesarean delivery, and forceps or ventouse application during delivery. History and examination was taken in each patient before delivery and hemoglobin and hematocrit were noted before and after delivery. Progress of labor was monitored and each patient was randomized into one of the four groups according to the dose of oxytocin to be given. Results Increasing doses of oxytocin resulted in decrease in duration of 3rd stage of labor and amount of blood loss. Conclusion Third stage of labor and amount of blood loss significantly reduced by increasing the dose of oxytocin to 30 IU. How to cite this article Sawai D, Sharma SK, Jain G. Effect of Different Doses of Intraumbilical Oxytocin on Third Stage of Labor. J South Asian Feder Obst Gynae 2016;8(4):286-289.


2013 ◽  
Vol 98 (Suppl 1) ◽  
pp. A85.2-A85
Author(s):  
F D’Antonio ◽  
A Khalil ◽  
T Dias ◽  
A Bhide ◽  
B Thilaganathan

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