scholarly journals OC11.04: Second trimester cervical length and spontaneous preterm birth in twin pregnancies

2013 ◽  
Vol 42 (s1) ◽  
pp. 22-22
Author(s):  
F. D'Antonio ◽  
A. Khalil ◽  
A. Bhide ◽  
B. Thilaganathan
Keyword(s):  
Preterm Birth ◽  
Cervical Length ◽  
Second Trimester ◽  
Spontaneous Preterm Birth ◽  
Twin Pregnancies

Association Between Second-Trimester Cervical Length and Spontaneous Preterm Birth in Twin Pregnancies

2010 ◽  
Vol 29 (12) ◽  
pp. 1733-1739 ◽  
Author(s):  
Nathan S. Fox ◽  
Andrei Rebarber ◽  
Ashley S. Roman ◽  
Chad K. Klauser ◽  
Daniel H. Saltzman
Keyword(s):  
Preterm Birth ◽  
Cervical Length ◽  
Second Trimester ◽  
Spontaneous Preterm Birth ◽  
Twin Pregnancies

Prediction of spontaneous preterm birth in asymptomatic twin pregnancies with the use of combined fetal fibronectin and cervical length

2009 ◽  
Vol 201 (3) ◽  
pp. 313.e1-313.e5 ◽  
Author(s):  
Nathan S. Fox ◽  
Daniel H. Saltzman ◽  
Chad K. Klauser ◽  
Danielle Peress ◽  
Christina V. Gutierrez ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Cervical Length ◽  
Spontaneous Preterm Birth ◽  
Fetal Fibronectin ◽  
Twin Pregnancies

775: Prediction of spontaneous preterm birth and very preterm birth in twin pregnancies using the change in cervical length over time

2008 ◽  
Vol 199 (6) ◽  
pp. S220
Author(s):  
Nathan Fox ◽  
Andrei Rebarber ◽  
Chad Klauser ◽  
Christine Ggtierrez ◽  
Danielle Peress ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Cervical Length ◽  
Spontaneous Preterm Birth ◽  
Very Preterm ◽  
Very Preterm Birth ◽  
Twin Pregnancies ◽  
Over Time

The Novel Ultrasonographic Marker of Uterocervical Angle for Prediction of Spontaneous Preterm Birth in Singleton and Twin Pregnancies: A Systematic Review and Meta-Analysis

2021 ◽  
pp. 1-7
Author(s):  
Kamran Hessami ◽  
Maryam Kasraeian ◽  
Álvaro Sepúlveda-Martínez ◽  
Mauro Cristian Parra-Cordero ◽  
Homeira Vafaei ◽  
...  
Keyword(s):  
Systematic Review ◽  
Preterm Birth ◽  
Meta Analysis ◽  
Predictive Marker ◽  
Second Trimester ◽  
Spontaneous Preterm Birth ◽  
Increased Risk ◽  
Study Heterogeneity ◽  
Mean Differences ◽  
Twin Pregnancies

The alteration of the uterocervical angle (UCA) has been proposed to play an important role in spontaneous preterm birth (sPTB). The aim of this systematic review and meta-analysis was to evaluate the evidence on the UCA predictive role in sPTB. In this study, PubMed, Web of Science, Scopus, and Google scholar were systematically searched from inception up to June 2020. Inter-study heterogeneity was also assessed using Cochrane’s <i>Q</i> test and the <i>I</i><sup>2</sup> statistic. Afterward, the random-effects model was used to pool the weighted mean differences (WMDs) and the corresponding 95% confidence intervals (CIs). Eleven articles that reported second-trimester UCA of 5,061 pregnancies were included in this study. Our meta-analysis results indicate that a wider UCA significantly increases the risk of sPTB in following cases: all pregnancies (WMD = 15.25, 95% CI: 11.78–18.72, <i>p</i> &#x3c; 0.001; <i>I</i><sup>2</sup> = 75.9%, <i>p</i> &#x3c; 0.001), singleton (WMD = 14.43, 95% CI: 8.79–20.06, <i>p</i> &#x3c; 0.001; <i>I</i><sup>2</sup> = 82.4%, <i>p</i> &#x3c; 0.001), and twin pregnancies (WMD = 15.14, 95% CI: 13.42–16.87, <i>p</i> &#x3c; 0.001; <i>I</i><sup>2</sup> = 0.0%, <i>p</i> = 0.464). A wider ultrasound-measured UCA in the second trimester seems to be associated with the increased risk of sPTB in both singleton and twin pregnancies, which reinforces the clinical evidence that UCA has the potential to be used as a predictive marker of sPTB.

Predictive Value of Mid-Trimester Cervical Measurement Data Combined With Maternal Characteristics for Twin Preterm Birth at < 32 Weeks: A Retrospective Analysis and External Validation Study

2021 ◽  
Author(s):  
Jun Zhang ◽  
Wenqiang Zhan ◽  
Yanling Lin ◽  
Danlin Yang ◽  
Xiaoying Xue ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Predictive Value ◽  
False Positive Rate ◽  
External Validation ◽  
Measurement Data ◽  
Cervical Length ◽  
Spontaneous Preterm Birth ◽  
Maternal Characteristics ◽  
Individual Probability ◽  
Twin Pregnancies

Abstract Objective The purpose of this study was to develop a dynamic model to predict the risk of spontaneous preterm birth at < 32 weeks in twin pregnancy. Methods Women with twin pregnancies were followed up from January 2017 to December 2019 in two tertiary medical centres—data from one were used to construct the model, and data from the other were used to evaluate the model. Data on maternal demographic characteristics, transvaginal cervical length and funnelling during 20–24 weeks were extracted. The prediction model was constructed with independent variables determined by logistic regression analyses. Results After applying specified exclusion criteria, an algorithm with maternal and biophysical factors was developed based on 92 twin pregnancies with a preterm birth < 32 weeks and 672 twin pregnancies with a delivery ≥ 32 weeks. It was then evaluated among 36 pregnancies with a preterm birth < 32 weeks and 261 pregnancies with a delivery ≥ 32 weeks in a second tertiary centre without specific training. The model reached a sensitivity of 78.26%, specificity of 88.84%, false positive rate of 11.16% and negative predictive value of 96.76%; ROC characteristics proved that the model was superior to any single parameter with an AUC of 0.856. Conclusions We developed and validated a dynamic nomogram model to predict the individual probability of early preterm birth in order to better represent the complex aetiology of twin pregnancies and hopefully improve the prediction and indication of interventions.

scholarly journals Uterocervical Angle Measurement Improves Prediction of Preterm Birth in Twin Gestation

2017 ◽  
Vol 35 (07) ◽  
pp. 648-654 ◽  
Author(s):  
Emily Tenbrink ◽  
Mitchell Onslow ◽  
Avinash Patil ◽  
Jordan Knight
Keyword(s):  
Preterm Birth ◽  
Transvaginal Ultrasound ◽  
Cervical Length ◽  
Angle Measurement ◽  
Spontaneous Preterm Birth ◽  
Increased Risk ◽  
The Mean ◽  
Gestational Age At Birth ◽  
Twin Pregnancies ◽  
Better Than

Objective Twin pregnancies are associated with an increased risk of spontaneous preterm birth. Our objective was to compare the performance of uterocervical angle to cervical length as predictors of spontaneous preterm birth in this population. Methods We conducted a retrospective cohort study of twin gestations at a single center from May 2008 to 2016 who received a transvaginal ultrasound for the evaluation of the cervix between 16 0/7 and 23 0/7 weeks. The primary outcome was prediction of preterm birth <28 and <32 weeks by uterocervical angle and cervical length. Results Among 259 women with twin gestation, the mean gestational age at birth was 34.83 ± 3.48 weeks. Receiver operator characteristic curves demonstrated optimal prediction of spontaneous preterm birth prior to 32 weeks at a uterocervical angle >110° (80% sensitivity, 82% specificity) [odds ratio (OR), 15.7 (95% confidence interval (CI), 7.2–34.4)] versus cervical length <20 mm (53% sensitivity, 85% specificity; p < 0.001, OR, 6.4 [95% CI, 2.3–17.8]) and similarly, prior to 28 weeks at a uterocervical angle >114° (OR, 24.3 [95% CI, 6.7–88.5]) compared with cervical length <20 mm (OR, 11.4 [95% CI, 3.5–36.7]). Conclusion Uterocervical angles >110° performed better than cervical length for the prediction of spontaneous preterm birth in twin gestations.

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