scholarly journals Nuchal translucency and major congenital heart defects in fetuses with normal karyotype: a meta-analysis

2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
A. Sotiriadis ◽  
S. Papatheodorou ◽  
M. Eleftheriades ◽  
G. Makrydimas
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Meta Analysis ◽  
Normal Karyotype ◽  
Nuchal Translucency

Prenatal screening for serious congenital heart defects using nuchal translucency: a meta-analysis

2008 ◽  
Vol 28 (12) ◽  
pp. 1094-1104 ◽  
Author(s):  
Nicholas J. Wald ◽  
Joan K. Morris ◽  
Kate Walker ◽  
John M. Simpson
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Prenatal Screening ◽  
Heart Defects ◽  
Meta Analysis ◽  
Nuchal Translucency

scholarly journals Children Born with Congenital Heart Defects and Growth Restriction at Birth: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 17 (9) ◽  
pp. 3056 ◽  
Author(s):  
Ali Ghanchi ◽  
Neil Derridj ◽  
Damien Bonnet ◽  
Nathalie Bertille ◽  
Laurent J. Salomon ◽  
...  
Keyword(s):  
Systematic Review ◽  
Congenital Heart Defects ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Congenital Heart ◽  
Heart Defects ◽  
Data Extraction ◽  
Meta Analysis ◽  
Adverse Outcomes ◽  
Growth Restriction

Newborns with congenital heart defects tend to have a higher risk of growth restriction, which can be an independent risk factor for adverse outcomes. To date, a systematic review of the relation between congenital heart defects (CHD) and growth restriction at birth, most commonly estimated by its imperfect proxy small for gestational age (SGA), has not been conducted. Objective: To conduct a systematic review and meta-analysis to estimate the proportion of children born with CHD that are small for gestational age (SGA). Methods: The search was carried out from inception until 31 March 2019 on Pubmed and Embase databases. Studies were screened and selected by two independent reviewers who used a predetermined data extraction form to obtain data from studies. Bias was assessed using the Critical Appraisal Skills Programme (CASP) checklist. The database search identified 1783 potentially relevant publications, of which 38 studies were found to be relevant to the study question. A total of 18 studies contained sufficient data for a meta-analysis, which was done using a random effects model. Results: The pooled proportion of SGA in all CHD was 20% (95% CI 16%–24%) and 14% (95% CI 13%–16%) for isolated CHD. Proportion of SGA varied across different CHD ranging from 30% (95% CI 24%–37%) for Tetralogy of Fallot to 12% (95% CI 7%–18%) for isolated atrial septal defect. The majority of studies included in the meta-analysis were population-based studies published after 2010. Conclusion: The overall proportion of SGA in all CHD was 2-fold higher whereas for isolated CHD, 1.4-fold higher than the expected proportion in the general population. Although few studies have looked at SGA for different subtypes of CHD, the observed variability of SGA by subtypes suggests that growth restriction at birth in CHD may be due to different pathophysiological mechanisms.

scholarly journals OC10.05: *Increased nuchal translucency in congenital heart defects: associations with mortality

2021 ◽  
Vol 58 (S1) ◽  
pp. 32-32
Author(s):  
R. Kristensen ◽  
C. Omann ◽  
J.W. Gaynor ◽  
Y. Dori ◽  
C.K. Ekelund ◽  
...  
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Nuchal Translucency ◽  
Increased Nuchal Translucency

scholarly journals Prenatal Alcohol Exposure and Congenital Heart Defects: A Meta-Analysis

PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0130681 ◽  
Author(s):  
Jiaomei Yang ◽  
Huizhen Qiu ◽  
Pengfei Qu ◽  
Ruo Zhang ◽  
Lingxia Zeng ◽  
...  
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Prenatal Alcohol Exposure ◽  
Heart Defects ◽  
Meta Analysis ◽  
Alcohol Exposure ◽  
Prenatal Alcohol

Hyperhomocysteinemia andMTHFR polymorphisms in association with orofacial clefts and congenital heart defects: A meta-analysis

2007 ◽  
Vol 143A (9) ◽  
pp. 952-960 ◽  
Author(s):  
Anna Verkleij-Hagoort ◽  
Johannes Bliek ◽  
Fakhredin Sayed-Tabatabaei ◽  
Nicolette Ursem ◽  
Eric Steegers ◽  
...  
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Meta Analysis ◽  
Orofacial Clefts
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